The PIM1 kinase is a critical component of a survival pathway activated by docetaxel and promotes survival of docetaxel-treated prostate cancer cells.
about
Drug resistance in castration resistant prostate cancer: resistance mechanisms and emerging treatment strategiesTricyclic Benzo[cd]azulenes selectively inhibit activities of Pim kinases and restrict growth of Epstein-Barr virus-transformed cellsCell-permeable Carboxyl-terminal p27Kip1 Peptide Exhibits Anti-tumor Activity by Inhibiting Pim-1 KinaseAssociation of Nuclear PIM1 Expression with Lymph Node Metastasis and Poor Prognosis in Patients with Lung Adenocarcinoma and Squamous Cell CarcinomaPIM1 kinase as a target for cancer therapyInduction of microRNA-1 by myocardin in smooth muscle cells inhibits cell proliferationNeuroendocrine-derived peptides promote prostate cancer cell survival through activation of IGF-1R signaling.Pim-selective inhibitor DHPCC-9 reveals Pim kinases as potent stimulators of cancer cell migration and invasionPharmacologic inhibition of Pim kinases alters prostate cancer cell growth and resensitizes chemoresistant cells to taxanes.Phenethyl isothiocyanate sensitizes androgen-independent human prostate cancer cells to docetaxel-induced apoptosis in vitro and in vivo.Androgen deprivation therapy has no effect on Pim-1 expression in a mouse model of prostate cancer.ERG deregulation induces PIM1 over-expression and aneuploidy in prostate epithelial cells.Regulation of Skp2 levels by the Pim-1 protein kinaseResveratrol Inhibits IL-6-Induced Transcriptional Activity of AR and STAT3 in Human Prostate Cancer LNCaP-FGC Cells.Pim-1 knockdown potentiates paclitaxel-induced apoptosis in human hormone-refractory prostate cancers through inhibition of NHEJ DNA repair.Pim-1 kinase is a target of miR-486-5p and eukaryotic translation initiation factor 4E, and plays a critical role in lung cancer.Clinical and biological significance of PIM1 kinase in osteosarcoma.The over-expression of Pim-2 promote the tumorigenesis of prostatic carcinoma through phosphorylating eIF4B.Targeting PIM kinase enhances the activity of sunitinib in renal cell carcinoma.IL-6 stimulates STAT3 and Pim-1 kinase in pancreatic cancer cell lines.Sorafenib decreases proliferation and induces apoptosis of prostate cancer cells by inhibition of the androgen receptor and Akt signaling pathwaysHuman Cytomegalovirus Immediate-Early 1 Protein Rewires Upstream STAT3 to Downstream STAT1 Signaling Switching an IL6-Type to an IFNγ-Like ResponseIdentification of ING4 (inhibitor of growth 4) as a modulator of docetaxel sensitivity in human lung adenocarcinomaActivation of Pim Kinases Is Sufficient to Promote Resistance to MET Small-Molecule Inhibitors.Cancer-associated fibroblasts promote endometrial cancer growth via activation of interleukin-6/STAT-3/c-Myc pathway.PIM1 polymorphism and PIM1 expression as predisposing factors of esophageal squamous cell carcinoma in the Asian population.Signal transduction in the development of pulmonary arterial hypertensionPim-1 kinase expression predicts radiation response in squamocellular carcinoma of head and neck and is under the control of epidermal growth factor receptor.Characterization and functional analysis of a slow cycling stem cell-like subpopulation in pancreas adenocarcinoma.Why target PIM1 for cancer diagnosis and treatment?The PIM family of serine/threonine kinases in cancer.PIM kinases: an overview in tumors and recent advances in pancreatic cancer.MicroRNA-181a promotes docetaxel resistance in prostate cancer cells.IFITM1 suppression blocks proliferation and invasion of aromatase inhibitor-resistant breast cancer in vivo by JAK/STAT-mediated induction of p21.Hypoxia-responsive miR-124 and miR-144 reduce hypoxia-induced autophagy and enhance radiosensitivity of prostate cancer cells via suppressing PIM1.Radiosensitization of TPGS-emulsified docetaxel-loaded poly(lactic-co-glycolic acid) nanoparticles in CNE-1 and A549 cells.Regulation of prostate stromal fibroblasts by the PIM1 protein kinase.The retinoblastoma tumor suppressor modulates DNA repair and radioresponsiveness.Nuclear factor-kappa B and interleukin-6 related docetaxel resistance in castration-resistant prostate cancer.The first Keystone Symposia Conference on pulmonary vascular isease and right ventricular dysfunction: Current concepts and future therapies.
P2860
Q26796704-3279D1C6-C736-4EDB-AADB-E0A30D4962B7Q27316853-EC4F6387-5391-4C6A-B872-6C6351B92BB1Q27665709-D7A6138C-69A7-4D5C-8926-1B2DB78A1972Q27853352-5CFC073A-A377-4E02-B153-8F069D37F719Q28261162-0EADBE38-7969-4C85-9406-423226ED1872Q28297726-93F26F3E-2A74-4EAF-BB00-6DF0258CE32EQ30412002-F50B31D1-391B-465C-8657-9E6EA22A6D3EQ30497339-DF58A048-205D-4079-8985-B46CB8B1BA79Q33597393-25809B38-6900-415E-8248-A5233AF0D635Q33724512-B02A87DB-5E8E-4D64-9319-89F12C0EF466Q33751248-BA67BC36-7A19-4CFE-8D7F-61E9DA64A6E5Q34091302-1BF03406-86AC-4D22-9917-40F7EB485ACBQ34121488-A32929B3-D170-42EB-9A0C-074EC22BF8DDQ34360539-10E845D8-2D7B-4AF9-9853-ECD6B9066134Q34391862-0E0B35E8-B905-4125-8BED-70083B164346Q34422999-EF79559A-A050-4C3C-BB88-F2B32AE7C227Q34674917-55A46FC4-57C5-4624-A09E-D2BB244321E0Q34787502-E440E075-D30E-46AE-9BEA-02877B3915F5Q35623092-71D62B8D-B746-415D-9D14-C39E7A00F658Q35916583-5D6F0090-A509-4011-A2F8-A0954F349B06Q35963384-9FC7C117-964B-42CC-888C-C5C7802D0FA0Q36069672-6E8D310D-D3F0-4E6B-8A2E-235F62935718Q36130919-F5EC912D-79FC-4052-85B1-B4D695AF8D93Q36383040-3F8DDBD7-171F-4327-BD8F-4DBB24AC169CQ36878675-E36B234A-D5A4-4D37-9D74-6F6613DF5E36Q36924453-01100571-C2DA-4D01-BDC1-9EFF7AAF4CD0Q37133785-6BF27EEE-8142-41BB-81DF-32E68AE54E06Q37229921-68927DD8-9D0C-41D8-BDDA-101EA9CB49FDQ37418677-E4AA8EB2-35BA-4B94-AF40-771B2E26DF26Q37797472-15A0AC15-67D6-4823-AA7B-CE79B59CD258Q38098139-509A8256-3865-4152-A95B-83B015B695A4Q38209606-DC50F688-0598-4146-BF2A-18A12A833FEDQ38704252-BCE735E7-BD99-4F53-93F0-8EDF186CB865Q38707618-3500E2B5-A6E8-459C-8F31-47D330B03F2BQ38785225-6FE069B8-E6F8-4209-8848-491BD64542E8Q38816559-0BCC9FEA-D51B-4B4C-9FB3-178C82ABFC08Q38934636-22EF9EBB-F0A6-46A1-ACA4-129F5915DECDQ38962238-CCF23958-A818-430F-93A2-9DE03B25A4BEQ39265565-CB2323D8-B89B-44DC-BBF2-C48872CBEFA2Q39353707-E443A2B1-1CA4-48CA-A670-1FD282E73444
P2860
The PIM1 kinase is a critical component of a survival pathway activated by docetaxel and promotes survival of docetaxel-treated prostate cancer cells.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
The PIM1 kinase is a critical ...... treated prostate cancer cells.
@en
The PIM1 kinase is a critical ...... treated prostate cancer cells.
@nl
type
label
The PIM1 kinase is a critical ...... treated prostate cancer cells.
@en
The PIM1 kinase is a critical ...... treated prostate cancer cells.
@nl
prefLabel
The PIM1 kinase is a critical ...... treated prostate cancer cells.
@en
The PIM1 kinase is a critical ...... treated prostate cancer cells.
@nl
P2093
P2860
P356
P1476
The PIM1 kinase is a critical ...... -treated prostate cancer cells
@en
P2093
Marina Zemskova
Michael Lilly
Svetlana Bashkirova
P2860
P304
20635-20644
P356
10.1074/JBC.M709479200
P407
P50
P577
2008-04-21T00:00:00Z