Aurora A kinase RNAi and small molecule inhibition of Aurora kinases with VE-465 induce apoptotic death in multiple myeloma cells.
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Aurora Kinases and Potential Medical Applications of Aurora Kinase Inhibitors: A ReviewPhase I study of MLN8237--investigational Aurora A kinase inhibitor--in relapsed/refractory multiple myeloma, non-Hodgkin lymphoma and chronic lymphocytic leukemia.A novel Aurora-A kinase inhibitor MLN8237 induces cytotoxicity and cell-cycle arrest in multiple myelomaConditional ablation of Ikkb inhibits melanoma tumor development in mice.Update on aurora kinase inhibitors in gynecologic malignancies.Update on Aurora Kinase Targeted Therapeutics in Oncology.Aurora kinase inhibitors as anticancer molecules.In vitro anti-myeloma activity of the Aurora kinase inhibitor VE-465.Aurora kinase inhibitors synergize with paclitaxel to induce apoptosis in ovarian cancer cellsIdentifying and classifying biomedical perturbations in text.The potential role of Aurora kinase inhibitors in haematological malignancies.Inhibition of aurora kinases for tailored risk-adapted treatment of multiple myelomaA G-quadruplex stabilizer induces M-phase cell cycle arrestCentrosomes and myeloma; aneuploidy and proliferation.Glioma pathogenesis-related protein 1 induces prostate cancer cell death through Hsc70-mediated suppression of AURKA and TPX2.From cell biology to therapy: ENMD-2076 in the treatment of multiple myeloma.ENMD-2076 for hematological malignancies.Dose selection for the investigational anticancer agent alisertib (MLN8237): Pharmacokinetics, pharmacodynamics, and exposure-safety relationships.Antimyeloma activity of a multitargeted kinase inhibitor, AT9283, via potent Aurora kinase and STAT3 inhibition either alone or in combination with lenalidomide.MMSET deregulation affects cell cycle progression and adhesion regulons in t(4;14) myeloma plasma cells.The therapeutic potential of cell cycle targeting in multiple myeloma.A phase II study of AT9283, an aurora kinase inhibitor, in patients with relapsed or refractory multiple myeloma: NCIC clinical trials group IND.191.Phase 1 study of the investigational Aurora A kinase inhibitor alisertib (MLN8237) in East Asian cancer patients: pharmacokinetics and recommended phase 2 dose.
P2860
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P2860
Aurora A kinase RNAi and small molecule inhibition of Aurora kinases with VE-465 induce apoptotic death in multiple myeloma cells.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Aurora A kinase RNAi and small ...... ath in multiple myeloma cells.
@en
type
label
Aurora A kinase RNAi and small ...... ath in multiple myeloma cells.
@en
prefLabel
Aurora A kinase RNAi and small ...... ath in multiple myeloma cells.
@en
P2093
P2860
P1433
P1476
Aurora A kinase RNAi and small ...... ath in multiple myeloma cells.
@en
P2093
Andrew Belch
Christopher Maxwell
Claudia Naber
Heidi Chau
Jonathan Keats
Linda Pilarski
Robert Evans
Tamara Checkland
Tara Steffler
Tony Reiman
P2860
P304
P356
10.1080/10428190701824544
P577
2008-03-01T00:00:00Z