MMSET deregulation affects cell cycle progression and adhesion regulons in t(4;14) myeloma plasma cells.
about
The histone methyltransferase, NSD2, enhances androgen receptor-mediated transcriptionClinical use and applications of histone deacetylase inhibitors in multiple myelomaGain-of-function mutation of chromatin regulators as a tumorigenic mechanism and an opportunity for therapeutic interventionDrug resistance in multiple myeloma: latest findings and new concepts on molecular mechanisms.Exploring the developmental mechanisms underlying Wolf-Hirschhorn Syndrome: Evidence for defects in neural crest cell migrationAuditory hair cell defects as potential cause for sensorineural deafness in Wolf-Hirschhorn syndromeDifferential effect of MMSET mRNA levels on survival to first-line FOLFOX and second-line docetaxel in gastric cancer.A novel functional role for MMSET in RNA processing based on the link between the REIIBP isoform and its interaction with the SMN complexMMSET: role and therapeutic opportunities in multiple myeloma.Cutting edge genomics reveal new insights into tumour development, disease progression and therapeutic impacts in multiple myeloma.In vitro histone lysine methylation by NSD1, NSD2/MMSET/WHSC1 and NSD3/WHSC1L.Histone lysine methyltransferase Wolf-Hirschhorn syndrome candidate 1 is involved in human carcinogenesis through regulation of the Wnt pathway.Inhibition of Nuclear Receptor Binding SET Domain 2/Multiple Myeloma SET Domain by LEM-06 Implication for Epigenetic Cancer Therapies.The antigenic landscape of multiple myeloma: mass spectrometry (re)defines targets for T-cell-based immunotherapyPhosphorylation-mediated EZH2 inactivation promotes drug resistance in multiple myeloma.The histone methyltransferase MMSET/WHSC1 activates TWIST1 to promote an epithelial-mesenchymal transition and invasive properties of prostate cancer.Genome-wide pharmacologic unmasking identifies tumor suppressive microRNAs in multiple myeloma.A PWWP Domain of Histone-Lysine N-Methyltransferase NSD2 Binds to Dimethylated Lys-36 of Histone H3 and Regulates NSD2 Function at Chromatin.The molecular characterization and clinical management of multiple myeloma in the post-genome era.Plasma membrane proteomics identifies biomarkers associated with MMSET overexpression in T(4;14) multiple myeloma.NSD2 contributes to oncogenic RAS-driven transcription in lung cancer cells through long-range epigenetic activation.MMSET stimulates myeloma cell growth through microRNA-mediated modulation of c-MYC.The genetic architecture of multiple myeloma.Monoclonal antibodies: potential new therapeutic treatment against multiple myeloma.Genomic instability in multiple myeloma: mechanisms and therapeutic implications.Epigenetic modulating agents as a new therapeutic approach in multiple myeloma.Mind the methyl: methyllysine binding proteins in epigenetic regulation.Current and potential epigenetic targets in multiple myeloma.Epigenetic modifiers in normal and malignant hematopoiesis.miR-29s: a family of epi-miRNAs with therapeutic implications in hematologic malignancies.Mechanisms and Clinical Applications of Genome Instability in Multiple Myeloma.MMSET regulates expression of IRF4 in t(4;14) myeloma and its silencing potentiates the effect of bortezomib.Epigenetic mechanisms of cell adhesion-mediated drug resistance in multiple myeloma.H3K27 Methylation: A Focal Point of Epigenetic Deregulation in Cancer.MMSET is dynamically regulated during cell-cycle progression and promotes normal DNA replication.Epigenetic modifications in multiple myeloma: recent advances on the role of DNA and histone methylation.The Role of Nuclear Receptor-Binding SET Domain Family Histone Lysine Methyltransferases in Cancer.Characterization of the EZH2-MMSET histone methyltransferase regulatory axis in cancer.Impact of Genes Highly Correlated with MMSET Myeloma on the Survival of Non-MMSET Myeloma Patients.Overexpression of EZH2 in multiple myeloma is associated with poor prognosis and dysregulation of cell cycle control.
P2860
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P2860
MMSET deregulation affects cell cycle progression and adhesion regulons in t(4;14) myeloma plasma cells.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
MMSET deregulation affects cell cycle progression and adhesion regulons in t
@nl
MMSET deregulation affects cel ...... t(4;14) myeloma plasma cells.
@en
type
label
MMSET deregulation affects cell cycle progression and adhesion regulons in t
@nl
MMSET deregulation affects cel ...... t(4;14) myeloma plasma cells.
@en
prefLabel
MMSET deregulation affects cell cycle progression and adhesion regulons in t
@nl
MMSET deregulation affects cel ...... t(4;14) myeloma plasma cells.
@en
P2093
P2860
P50
P356
P1433
P1476
MMSET deregulation affects cel ...... n t(4;14) myeloma plasma cells
@en
P2093
Athanasia Avramidou
David Gonzalez
Faith E Davies
Fiona M Ross
Jose L R Brito
Julie A E Irving
Nicola J M Brown
P2860
P356
10.3324/HAEMATOL.13426
P577
2008-12-04T00:00:00Z