RalGDS couples growth factor signaling to Akt activation.
about
Ras family of small GTPases in immunity and inflammationRas superfamily GEFs and GAPs: validated and tractable targets for cancer therapy?Ral GTPases: crucial mediators of exocytosis and tumourigenesisAberrant overexpression of the Rgl2 Ral small GTPase-specific guanine nucleotide exchange factor promotes pancreatic cancer growth through Ral-dependent and Ral-independent mechanismsThe ral exchange factor rgl2 promotes cardiomyocyte survival and inhibits cardiac fibrosisRequirement of JIP1-mediated c-Jun N-terminal kinase activation for obesity-induced insulin resistance.Ral small GTPase signaling and oncogenesis: More than just 15minutes of fameCdc42p-interacting protein Bem4p regulates the filamentous-growth mitogen-activated protein kinase pathway.RalA functions as an indispensable signal mediator for the nutrient-sensing systemThe anti-inflammatory TIPE2 is an inhibitor of the oncogenic Ras.RalGPS2 Is Essential for Survival and Cell Cycle Progression of Lung Cancer Cells Independently of Its Established Substrates Ral GTPases.RILP suppresses invasion of breast cancer cells by modulating the activity of RalA through interaction with RalGDSNegative Immune Regulator TIPE2 Promotes M2 Macrophage Differentiation through the Activation of PI3K-AKT Signaling PathwayMutations in the phosphatidylinositol-3-kinase pathway predict for antitumor activity of the inhibitor PX-866 whereas oncogenic Ras is a dominant predictor for resistance.The small GTPase RALA controls c-Jun N-terminal kinase-mediated FOXO activation by regulation of a JIP1 scaffold complexProtein phosphatase 2A isoforms utilizing Aβ scaffolds regulate differentiation through control of Akt protein.Principles of K-Ras effector organization and the role of oncogenic K-Ras in cancer initiation through G1 cell cycle deregulation.Early thyroid hormone-induced gene expression changes in N2a-β neuroblastoma cells.RalA suppresses early stages of Ras-induced squamous cell carcinoma progression.Structure, signaling and the drug discovery of the Ras oncogene protein.
P2860
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P2860
RalGDS couples growth factor signaling to Akt activation.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
RalGDS couples growth factor signaling to Akt activation.
@en
type
label
RalGDS couples growth factor signaling to Akt activation.
@en
prefLabel
RalGDS couples growth factor signaling to Akt activation.
@en
P2093
P2860
P356
P1476
RalGDS couples growth factor signaling to Akt activation.
@en
P2093
Larry A Feig
Richard Wong
Yansheng Hao
P2860
P304
P356
10.1128/MCB.01917-07
P407
P577
2008-02-19T00:00:00Z