Human immunodeficiency virus type 1 escape from RNA interference.
about
Antisense-mediated inhibition of human immunodeficiency virus (HIV) replication by use of an HIV type 1-based vector results in severely attenuated mutants incapable of developing resistanceSmall interfering RNAs against the TAR RNA binding protein, TRBP, a Dicer cofactor, inhibit human immunodeficiency virus type 1 long terminal repeat expression and viral productionHIV-1 can escape from RNA interference by evolving an alternative structure in its RNA genomeIs HIV-1 RNA dimerization a prerequisite for packaging? Yes, no, probably?Lentiviral transduction of Tar Decoy and CCR5 ribozyme into CD34+ progenitor cells and derivation of HIV-1 resistant T cells and macrophagesCXCR4 and CCR5 shRNA transgenic CD34+ cell derived macrophages are functionally normal and resist HIV-1 infectionCCR5 Targeted Cell Therapy for HIV and Prevention of Viral EscapeFoamy virus vectors for HIV gene therapyHepatitis C Virus Replicons Escape RNA Interference Induced by a Short Interfering RNA Directed against the NS5b Coding RegionNairovirus RNA Sequences Expressed by a Semliki Forest Virus Replicon Induce RNA Interference in Tick CellsSilencing Viral InfectionSmall Interfering RNA Targeted to Hepatitis C Virus 5' Nontranslated Region Exerts Potent Antiviral EffectOptimization of linear double-stranded RNA for the production of multiple siRNAs targeting hepatitis C virusThe role of RNAi and microRNAs in animal virus replication and antiviral immunityAchieving HIV-1 Control through RNA-Directed Gene RegulationA genome-wide short hairpin RNA screening of jurkat T-cells for human proteins contributing to productive HIV-1 replicationCurrent progress and challenges in HIV gene therapyOptimal design and validation of antiviral siRNA for targeting HIV-1.Trafficking through the Rev/RRE pathway is essential for efficient inhibition of human immunodeficiency virus type 1 by an antisense RNA derived from the envelope gene.The efficacy of generating three independent anti-HIV-1 siRNAs from a single U6 RNA Pol III-expressed long hairpin RNA.Effective treatment of respiratory alphaherpesvirus infection using RNA interference.Selection of potent non-toxic inhibitory sequences from a randomized HIV-1 specific lentiviral short hairpin RNA library.Inhibition of coxsackievirus B3 replication by small interfering RNAs requires perfect sequence match in the central region of the viral positive strand.A re-examination of global suppression of RNA interference by HIV-1.Dual-targeting siRNAsHIVsirDB: a database of HIV inhibiting siRNAsA novel ribozyme-based prophylaxis inhibits influenza A virus replication and protects from severe disease.In silico modeling indicates the development of HIV-1 resistance to multiple shRNA gene therapy differs to standard antiretroviral therapy.Cell-type-specific aptamer and aptamer-small interfering RNA conjugates for targeted human immunodeficiency virus type 1 therapy.Safe, long-term hepatic expression of anti-HCV shRNA in a nonhuman primate modelAttenuation of HIV-1 replication in primary human cells with a designed zinc finger transcription factor.Unlocking the potential of the human genome with RNA interference.siRNA therapeutics: big potential from small RNAs.Antiviral effects of human immunodeficiency virus type 1-specific small interfering RNAs against targets conserved in select neurotropic viral strains.Inhibition of human immunodeficiency virus type 1 replication with artificial transcription factors targeting the highly conserved primer-binding site.An RNAi in silico approach to find an optimal shRNA cocktail against HIV-1.The interplay between virus infection and the cellular RNA interference machinery.HIV-1 RT-dependent DNAzyme expression inhibits HIV-1 replication without the emergence of escape viruses.Multiple shRNA combinations for near-complete coverage of all HIV-1 strainsDevelopment of resistance to RNAi in mammalian cells
P2860
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P2860
Human immunodeficiency virus type 1 escape from RNA interference.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Human immunodeficiency virus type 1 escape from RNA interference.
@en
type
label
Human immunodeficiency virus type 1 escape from RNA interference.
@en
prefLabel
Human immunodeficiency virus type 1 escape from RNA interference.
@en
P2093
P2860
P1433
P1476
Human immunodeficiency virus type 1 escape from RNA interference.
@en
P2093
Bharat Ramratnam
Daniel Boden
Frederick Lee
Lynne Tucker
Oliver Pusch
P2860
P304
11531-11535
P356
10.1128/JVI.77.21.11531-11535.2003
P407
P577
2003-11-01T00:00:00Z