Ternary Kv4.2 channels recapitulate voltage-dependent inactivation kinetics of A-type K+ channels in cerebellar granule neurons.
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Kv4.2 and accessory dipeptidyl peptidase-like protein 10 (DPP10) subunit preferentially form a 4:2 (Kv4.2:DPP10) channel complexIon channel macromolecular complexes in cardiomyocytes: roles in sudden cardiac deathDPP6 establishes the A-type K(+) current gradient critical for the regulation of dendritic excitability in CA1 hippocampal neuronsAugmentation of Kv4.2-encoded currents by accessory dipeptidyl peptidase 6 and 10 subunits reflects selective cell surface Kv4.2 protein stabilizationDipeptidyl peptidase-like protein 6 is required for normal electrophysiological properties of cerebellar granule cellsInhibitory effects of polyunsaturated fatty acids on Kv4/KChIP potassium channels.Molecular determinants of cardiac transient outward potassium current (I(to)) expression and regulationA novel DPP6 isoform (DPP6-E) can account for differences between neuronal and reconstituted A-type K(+) channels.Dynamic, nonlinear feedback regulation of slow pacemaking by A-type potassium current in ventral tegmental area neurons.The membrane protein MiRP3 regulates Kv4.2 channels in a KChIP-dependent manner.Incorporation of DPP6a and DPP6K variants in ternary Kv4 channel complex reconstitutes properties of A-type K current in rat cerebellar granule cells.Dipeptidyl-peptidase-like-proteins confer high sensitivity to the scorpion toxin AmmTX3 to Kv4-mediated A-type K+ channels.Kv4 channels underlie A-currents with highly variable inactivation time courses but homogeneous other gating properties in the nucleus tractus solitarii.K(V)4.3 N-terminal deletion mutant Δ2-39: effects on inactivation and recovery characteristics in both the absence and presence of KChIP2b.A new TASK for Dipeptidyl Peptidase-like Protein 6.Kv3.4 channel function and dysfunction in nociceptors.Regulation of voltage-gated potassium channels by PI(4,5)P2Modeling-independent elucidation of inactivation pathways in recombinant and native A-type Kv channels.A novel N-terminal motif of dipeptidyl peptidase-like proteins produces rapid inactivation of KV4.2 channels by a pore-blocking mechanism.Auxiliary KChIP4a suppresses A-type K+ current through endoplasmic reticulum (ER) retention and promoting closed-state inactivation of Kv4 channelsDistinct cellular distributions of Kv4 pore-forming and auxiliary subunits in rat dorsal root ganglion neurons.Kv4 accessory protein DPPX (DPP6) is a critical regulator of membrane excitability in hippocampal CA1 pyramidal neuronsDPP6 Localization in Brain Supports Function as a Kv4 Channel Associated ProteinAntibody-guided photoablation of voltage-gated potassium currentsThe dipeptidyl-peptidase-like protein DPP6 determines the unitary conductance of neuronal Kv4.2 channels.Association of the Kv1 family of K+ channels and their functional blueprint in the properties of auditory neurons as revealed by genetic and functional analyses.Stochastic and deterministic dynamics of intrinsically irregular firing in cortical inhibitory interneuronsWeighing the evidence for a ternary protein complex mediating A-type K+ currents in neurons.Kv4 Channels Underlie the Subthreshold-Operating A-type K-current in Nociceptive Dorsal Root Ganglion Neurons.Convergent modulation of Kv4.2 channel alpha subunits by structurally distinct DPPX and KChIP auxiliary subunits.Modulatory mechanisms and multiple functions of somatodendritic A-type K (+) channel auxiliary subunitsMechanisms of closed-state inactivation in voltage-gated ion channels.Transient outward potassium channel: a heart failure mediator.Multiple Kv channel-interacting proteins contain an N-terminal transmembrane domain that regulates Kv4 channel trafficking and gating.Activity-dependent gating of calcium spikes by A-type K+ channels controls climbing fiber signaling in Purkinje cell dendrites.Fly DPP10 acts as a channel ancillary subunit and possesses peptidase activity.T2N as a new tool for robust electrophysiological modeling demonstrated for mature and adult-born dentate granule cells.High-conductance states and A-type K+ channels are potential regulators of the conductance-current balance triggered by HCN channels.Kv4.2 channel activity controls intrinsic firing dynamics of arcuate kisspeptin neurons.Potassium Channel Gain of Function in Epilepsy: An Unresolved Paradox.
P2860
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P2860
Ternary Kv4.2 channels recapitulate voltage-dependent inactivation kinetics of A-type K+ channels in cerebellar granule neurons.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Ternary Kv4.2 channels recapit ...... in cerebellar granule neurons.
@en
type
label
Ternary Kv4.2 channels recapit ...... in cerebellar granule neurons.
@en
prefLabel
Ternary Kv4.2 channels recapit ...... in cerebellar granule neurons.
@en
P2093
P2860
P1476
Ternary Kv4.2 channels recapit ...... in cerebellar granule neurons
@en
P2093
Elaine Kwon
Jonathon Maffie
Jose A De Santiago-Castillo
Kevin Dougherty
Manuel Covarrubias
P2860
P304
P356
10.1113/JPHYSIOL.2007.150540
P407
P577
2008-02-14T00:00:00Z