Auto-oxidation and oligomerization of protein S on the apoptotic cell surface is required for Mer tyrosine kinase-mediated phagocytosis of apoptotic cells.
about
Gas6 is complexed to the soluble tyrosine kinase receptor Axl in human bloodThe Role of TAM Family Receptors in Immune Cell Function: Implications for Cancer TherapyProtein S protects neurons from excitotoxic injury by activating the TAM receptor Tyro3-phosphatidylinositol 3-kinase-Akt pathway through its sex hormone-binding globulin-like regionDBA/2J Haplotype on Distal Chromosome 2 Reduces Mertk Expression, Restricts Efferocytosis, and Increases Susceptibility to Atherosclerosis.Generation and phenotypic analysis of protein S-deficient mice.Association of plasma levels of Protein S with disease severity in multiple sclerosis.Engulfment signals and the phagocytic machinery for apoptotic cell clearance.Immunobiology of the TAM receptors.Protein S controls hypoxic/ischemic blood-brain barrier disruption through the TAM receptor Tyro3 and sphingosine 1-phosphate receptor.Increased hematopoietic cells in the mertk-/- mouse peritoneal cavity: a result of augmented migrationDendritic cells in systemic lupus erythematosusTAM receptor ligands in lupus: protein S but not Gas6 levels reflect disease activity in systemic lupus erythematosusDifferential TAM receptor-ligand-phospholipid interactions delimit differential TAM bioactivities.Protein S blocks the extrinsic apoptotic cascade in tissue plasminogen activator/N-methyl D-aspartate-treated neurons via Tyro3-Akt-FKHRL1 signaling pathway.Shedding of the Mer tyrosine kinase receptor is mediated by ADAM17 protein through a pathway involving reactive oxygen species, protein kinase Cδ, and p38 mitogen-activated protein kinase (MAPK).Accumulation and autofluorescence of phagocytized rod outer segment material in macrophages and microglial cellsTAM receptor signaling in immune homeostasis.Mer receptor tyrosine kinase mediates both tethering and phagocytosis of apoptotic cells.Targeting Axl with an high-affinity inhibitory aptamer.Therapeutic efficacy of Tyro3, Axl, and Mer tyrosine kinase agonists in collagen-induced arthritis.Vitamin K-dependent proteins GAS6 and Protein S and TAM receptors in patients of systemic lupus erythematosus: correlation with common genetic variants and disease activityRedox control of inflammation in macrophages.Mer tyrosine kinase (MerTK) promotes macrophage survival following exposure to oxidative stress.Biology of the TAM receptors.Coordinated expression of tyro3, axl, and mer receptors in macrophage ontogenySpecies-specific anticoagulant and mitogenic activities of murine protein S.Progressive multiple sclerosis.Circulating levels of soluble MER in lupus reflect M2c activation of monocytes/macrophages, autoantibody specificities and disease activityThe Mer receptor tyrosine kinase is expressed on discrete macrophage subpopulations and mainly uses Gas6 as its ligand for uptake of apoptotic cells.TAM receptors and the clearance of apoptotic cells.The "Phagocytic Synapse" and Clearance of Apoptotic Cells.Protein S and Gas6 induce efferocytosis of HIV-1-infected cells.Upregulation of anticoagulant proteins, protein S and tissue factor pathway inhibitor, in the mouse myocardium with cardio-specific TNF-α overexpression.
P2860
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P2860
Auto-oxidation and oligomerization of protein S on the apoptotic cell surface is required for Mer tyrosine kinase-mediated phagocytosis of apoptotic cells.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Auto-oxidation and oligomeriza ...... agocytosis of apoptotic cells.
@en
type
label
Auto-oxidation and oligomeriza ...... agocytosis of apoptotic cells.
@en
prefLabel
Auto-oxidation and oligomeriza ...... agocytosis of apoptotic cells.
@en
P1476
Auto-oxidation and oligomeriza ...... agocytosis of apoptotic cells.
@en
P2093
Emily Shacter
Hiroshi Uehara
P304
P356
10.4049/JIMMUNOL.180.4.2522
P407
P577
2008-02-01T00:00:00Z