17beta-hydroxysteroid dehydrogenase Type 1, and not Type 12, is a target for endocrine therapy of hormone-dependent breast cancer. - Wikidata - wikimedia - TriplyDB

17beta-hydroxysteroid dehydrogenase Type 1, and not Type 12, is a target for endocrine therapy of hormone-dependent breast cancer.

17beta-hydroxysteroid dehydrogenase Type 1, and not Type 12, is a target for endocrine therapy of hormone-dependent breast cancer.

http://www.wikidata.org/entity/Q40027067

about

Binary and ternary crystal structure analyses of a novel inhibitor with 17beta-HSD type 1: a lead compound for breast cancer therapy 17beta-hydroxysteroid dehydrogenase type 1 stimulates breast cancer by dihydrotestosterone inactivation in addition to estradiol production Creation of a free, Internet-accessible database: the Multiple Target Ligand Database Species used for drug testing reveal different inhibition susceptibility for 17beta-hydroxysteroid dehydrogenase type 1 Hydroxybenzothiazoles as new nonsteroidal inhibitors of 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1)Novel hydroxysteroid (17beta) dehydrogenase 1 inhibitors reverse estrogen-induced endometrial hyperplasia in transgenic mice Estrogen and androgen-converting enzymes 17β-hydroxysteroid dehydrogenase and their involvement in cancer: with a special focus on 17β-hydroxysteroid dehydrogenase type 1, 2, and breast cancer.The Activity of SN33638, an Inhibitor of AKR1C3, on Testosterone and 17β-Estradiol Production and Function in Castration-Resistant Prostate Cancer and ER-Positive Breast Cancer.The influence of bovine milk high or low in isoflavones on hepatic gene expression in mice.The anti-interleukin-6 antibody siltuximab down-regulates genes implicated in tumorigenesis in prostate cancer patients from a phase I study.The Role of Androgens in Normal and Malignant Breast Tissue.Comparison of functional proteomic analyses of human breast cancer cell lines T47D and MCF7 Aromatase, estrone sulfatase, and 17β-hydroxysteroid dehydrogenase: structure-function studies and inhibitor development.Human hydroxysteroid dehydrogenases and pre-receptor regulation: insights into inhibitor design and evaluation.Overexpression of 17β-hydroxysteroid dehydrogenase type 10 increases pheochromocytoma cell growth and resistance to cell death.Genetic polymorphisms and obesity influence estradiol decline during the menopause.Identification of Hydroxysteroid (17β) dehydrogenase type 12 (HSD17B12) as a CD8+ T-cell-defined human tumor antigen of human carcinomas Synergistic control of sex hormones by 17β-HSD type 7: a novel target for estrogen-dependent breast cancer.Endocrine resistance in breast cancer--An overview and update.The use of steroid sulfatase inhibitors as a novel therapeutic strategy against hormone-dependent endometrial cancer.Expression of estrogenicity genes in a lineage cell culture model of human breast cancer progression.Cysteine-10 on 17 β -Hydroxysteroid Dehydrogenase 1 Has Stabilizing Interactions in the Cofactor Binding Region and Renders Sensitivity to Sulfhydryl Modifying Chemicals.17beta-Hydroxysteroid dehydrogenase inhibitors: a patent review.Regulation of 17β-hydroxysteroid dehydrogenases in cancer: regulating steroid receptor at pre-receptor stage.Oestrogen and colorectal cancer: mechanisms and controversies.Crucial Role of 3-Bromoethyl in Removing the Estrogenic Activity of 17β-HSD1 Inhibitor 16β-(m-Carbamoylbenzyl)estradiol.Biochemical factors governing the steady-state estrone/estradiol ratios catalyzed by human 17beta-hydroxysteroid dehydrogenases types 1 and 2 in HEK-293 cells.Target deletion of the bifunctional type 12 17β-hydroxysteroid dehydrogenase in mice results in reduction of androgen and estrogen levels in heterozygotes and embryonic lethality in homozygotes.Blocking 17β-hydroxysteroid dehydrogenase type 1 in endometrial cancer: a potential novel endocrine therapeutic approach.MTLD, a Database of Multiple Target Ligands, the Updated Version.A validated and rapid high-performance liquid chromatography method for the quantification of conversion of radio-labelled sex steroids.Cytosolic and Transmembrane Protein Extraction Methods of Breast and Ovarian Cancer Cells: A Comparative Study

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P2860

17beta-hydroxysteroid dehydrogenase Type 1, and not Type 12, is a target for endocrine therapy of hormone-dependent breast cancer.

http://www.wikidata.org/entity/Q40027067

description

2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

@zh-tw

2008年论文

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2008年论文

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2008年论文

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name

17beta-hydroxysteroid dehydrog ...... rmone-dependent breast cancer.

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type

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17beta-hydroxysteroid dehydrog ...... rmone-dependent breast cancer.

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17beta-hydroxysteroid dehydrog ...... rmone-dependent breast cancer.

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P1433

International Journal of Cancer

P1476

17beta-hydroxysteroid dehydrog ...... ormone-dependent breast cancer

@en

P2093

Atul Purohit

http://www.w3.org/2001/XMLSchema#string

Barry V L Potter

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Gillian M Allan

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Harshani R Lawrence

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Helena J Tutill

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Joanna M Day

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Michael F C Parsons

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Michael J Reed

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Nigel Vicker

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Simon P Newman

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P2860

Focused libraries of 16-substituted estrone derivatives and modified e-ring steroids: inhibitors of 17beta-hydroxysteroid dehydrogenase type 1.

Inhibitors of 17 beta-hydroxysteroid dehydrogenases.

Human 17 beta-hydroxysteroid dehydrogenase type 1 and type 2 isoenzymes have opposite activities in cultured cells and characteristic cell- and tissue-specific expression.

P304

1931-1940

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scholarly article

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10.1002/IJC.23350

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9

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122

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2008-05-01T00:00:00Z

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5666026

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18183589

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