Signal strength dictates phosphoinositide 3-kinase contribution to Ras/extracellular signal-regulated kinase 1 and 2 activation via differential Gab1/Shp2 recruitment: consequences for resistance to epidermal growth factor receptor inhibition.

Signal strength dictates phosphoinositide 3-kinase contribution to Ras/extracellular signal-regulated kinase 1 and 2 activation via differential Gab1/Shp2 recruitment: consequences for resistance to epidermal growth factor receptor inhibition.

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http://www.wikidata.org/entity/Q40048491
Function, regulation and pathological roles of the Gab/DOS docking proteinsFunctional effects of PTPN11 (SHP2) mutations causing LEOPARD syndrome on epidermal growth factor-induced phosphoinositide 3-kinase/AKT/glycogen synthase kinase 3beta signalingPhosphorylation-dependent binding of 14-3-3 terminates signalling by the Gab2 docking proteinActivation of a novel estrogen receptor, GPER, is cardioprotective in male and female ratsInhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancerGenomic-wide analysis of lymphatic metastasis-associated genes in human hepatocellular carcinoma.Inhibition of triple-negative and Herceptin-resistant breast cancer cell proliferation and migration by Annexin A2 antibodies.Simultaneous targeting of PI3Kδ and a PI3Kδ-dependent MEK1/2-Erk1/2 pathway for therapy in pediatric B-cell acute lymphoblastic leukemia.Multiple mechanisms are responsible for transactivation of the epidermal growth factor receptor in mammary epithelial cells.Dual PI3K/mTOR inhibitor BEZ235 exerts extensive antitumor activity in HER2-positive gastric cancer.A phase I/II, non-randomized, feasibility/safety and efficacy study of the combination of everolimus, cetuximab and capecitabine in patients with advanced pancreatic cancer.Integration of Receptor Tyrosine Kinases Determines Sensitivity to PI3Kα-selective Inhibitors in Breast Cancer.Receptor tyrosine kinase (RTK) signalling in the control of neural stem and progenitor cell (NSPC) development.PI3K is required for both basal and LPA-induced DNA synthesis in oral carcinoma cells.Modelling reveals novel roles of two parallel signalling pathways and homeostatic feedbacks in yeast.Survival of pancreatic cancer cells lacking KRAS function.PLC-γ and PI3K link cytokines to ERK activation in hematopoietic cells with normal and oncogenic Kras
P2860

Signal strength dictates phosphoinositide 3-kinase contribution to Ras/extracellular signal-regulated kinase 1 and 2 activation via differential Gab1/Shp2 recruitment: consequences for resistance to epidermal growth factor receptor inhibition.

Item
http://www.wikidata.org/entity/Q40048491
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Signal strength dictates phosp ...... th factor receptor inhibition.
@en
type
label
Signal strength dictates phosp ...... th factor receptor inhibition.
@en
prefLabel
Signal strength dictates phosp ...... th factor receptor inhibition.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932
P356
P1433
P1476
Signal strength dictates phosp ...... th factor receptor inhibition.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932