Genome-wide location analysis and expression studies reveal a role for p110 CUX1 in the activation of DNA replication genes.
about
CUX1 transcription factor is a downstream effector of the proteinase-activated receptor 2 (PAR2)Cut homeobox 1 causes chromosomal instability by promoting bipolar division after cytokinesis failure.Repression of human cytomegalovirus major immediate early gene expression by the cellular transcription factor CCAAT displacement protein.CUX1, a haploinsufficient tumour suppressor gene overexpressed in advanced cancers.Cut-like homeobox 1 (CUX1) regulates expression of the fat mass and obesity-associated and retinitis pigmentosa GTPase regulator-interacting protein-1-like (RPGRIP1L) genes and coordinates leptin receptor signaling.Long-range transcriptional regulation by the p110 CUX1 homeodomain protein on the ENCODE array.Ectopic expression of Cux1 is associated with reduced p27 expression and increased apoptosis during late stage cyst progression upon inactivation of Pkd1 in collecting ducts.RAS transformation requires CUX1-dependent repair of oxidative DNA damage.Transcriptional regulation of the human KiSS1 geneAutocrine Activation of the Wnt/β-Catenin Pathway by CUX1 and GLIS1 in Breast Cancers.HSET overexpression fuels tumor progression via centrosome clustering-independent mechanisms in breast cancer patientsTranscription of the human EAP1 gene is regulated by upstream components of a puberty-controlling Tumor Suppressor Gene network.CUX1 is a haploinsufficient tumor suppressor gene on chromosome 7 frequently inactivated in acute myeloid leukemiap110 CUX1 cooperates with E2F transcription factors in the transcriptional activation of cell cycle-regulated genes.Transcriptional activation of the Lats1 tumor suppressor gene in tumors of CUX1 transgenic mice.TCF4 (e2-2; ITF2): a schizophrenia-associated gene with pleiotropic effects on human disease.MicroRNA122 is a key regulator of α-fetoprotein expression and influences the aggressiveness of hepatocellular carcinoma.p110 CUX1 homeodomain protein stimulates cell migration and invasion in part through a regulatory cascade culminating in the repression of E-cadherin and occludin.The function of CUX1 in oxidative DNA damage repair is needed to prevent premature senescence of mouse embryo fibroblasts.CUX1 and E2F1 regulate coordinated expression of the mitotic complex genes Ect2, MgcRacGAP, and MKLP1 in S phase.CUX1 transcription factor is required for optimal ATM/ATR-mediated responses to DNA damage.The roles of CUX1 homeodomain proteins in the establishment of a transcriptional program required for cell migration and invasion.The DNA repair function of CUX1 contributes to radioresistance.Polycystic kidneys caused by sustained expression of Cux1 isoform p75.CUX1 Stimulates APE1 Enzymatic Activity and Increases the Resistance of Glioblastoma Cells to the Mono-Alkylating Agent, Temozolomide.Prenatal immune challenge compromises the normal course of neurogenesis during development of the mouse cerebral cortex.
P2860
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P2860
Genome-wide location analysis and expression studies reveal a role for p110 CUX1 in the activation of DNA replication genes.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Genome-wide location analysis ...... tion of DNA replication genes.
@en
type
label
Genome-wide location analysis ...... tion of DNA replication genes.
@en
prefLabel
Genome-wide location analysis ...... tion of DNA replication genes.
@en
P2093
P2860
P356
P1476
Genome-wide location analysis ...... tion of DNA replication genes.
@en
P2093
Alain Nepveu
Charles Vadnais
François Robert
Ginette Bérubé
Laurent Sansregret
Ryoko Harada
P2860
P304
P356
10.1093/NAR/GKM970
P577
2007-11-14T00:00:00Z