A high throughput live transparent animal bioassay to identify non-toxic small molecules or genes that regulate vertebrate fat metabolism for obesity drug development.
about
In silico molecular comparisons of C. elegans and mammalian pharmacology identify distinct targets that regulate feedingIdentification of novel inhibitors of dietary lipid absorption using zebrafishAutomated reporter quantification in vivo: high-throughput screening method for reporter-based assays in zebrafishOverexpression of Akt1 enhances adipogenesis and leads to lipoma formation in zebrafishZebrafish lipid metabolism: from mediating early patterning to the metabolism of dietary fat and cholesterol.ZeGlobalTox: An Innovative Approach to Address Organ Drug Toxicity Using Zebrafish.Halogenated bisphenol-A analogs act as obesogens in zebrafish larvae (Danio rerio).Diet-induced obesity in zebrafish shares common pathophysiological pathways with mammalian obesity.A New Ergosterol Analog, a New Bis-Anthraquinone and Anti-Obesity Activity of Anthraquinones from the Marine Sponge-Associated Fungus Talaromyces stipitatus KUFA 0207.The developing zebrafish (Danio rerio): a vertebrate model for high-throughput screening of chemical libraries.Regulation of C. elegans fat uptake and storage by acyl-CoA synthase-3 is dependent on NR5A family nuclear hormone receptor nhr-25.A whole-organism screen identifies new regulators of fat storage.Zebrafish obesogenic test: a tool for screening molecules that target adiposityLong-term hyperphagia and caloric restriction caused by low- or high-density husbandry have differential effects on zebrafish postembryonic development, somatic growth, fat accumulation and reproductionDisruption of ldlr causes increased LDL-c and vascular lipid accumulation in a zebrafish model of hypercholesterolemia.Elucidating cannabinoid biology in zebrafish (Danio rerio).The importance of NAD in multiple sclerosisOntogeny and nutritional control of adipogenesis in zebrafish (Danio rerio).A new model system swims into focus: using the zebrafish to visualize intestinal metabolism in vivo.Something worth dyeing for: molecular tools for the dissection of lipid metabolism in Caenorhabditis elegans.Zebrafish: gaining popularity in lipid research.Multifaceted approach to resveratrol bioactivity: Focus on antioxidant action, cell signaling and safety.Advances in zebrafish chemical screening technologies.Downregulation of Max dimerization protein 3 is involved in decreased visceral adipose tissue by inhibiting adipocyte differentiation in zebrafish and mice.Two-photon AIE bio-probe with large Stokes shift for specific imaging of lipid dropletsNrk2b-mediated NAD+ production regulates cell adhesion and is required for muscle morphogenesis in vivo: Nrk2b and NAD+ in muscle morphogenesis.Synthesis of a new fluorescent small molecule probe and its use for in vivo lipid imaging.A new type of biocompatible fluorescent probe AFN for fixed and live cell imaging of intracellular lipid droplets.Human prokinetic drugs promote gastrointestinal motility in zebrafish.Toxicity comparison of different active fractions extracted from radix Sophorae tonkinensis in zebrafish*.Wine lees modulate lipid metabolism and induce fatty acid remodelling in zebrafish.Cadmium exposure increases the risk of juvenile obesity: a human and zebrafish comparative study.Zebrafish as a Model for Obesity and Diabetes
P2860
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P2860
A high throughput live transparent animal bioassay to identify non-toxic small molecules or genes that regulate vertebrate fat metabolism for obesity drug development.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
A high throughput live transpa ...... for obesity drug development.
@en
type
label
A high throughput live transpa ...... for obesity drug development.
@en
prefLabel
A high throughput live transpa ...... for obesity drug development.
@en
P2093
P2860
P356
P1476
A high throughput live transpa ...... for obesity drug development.
@en
P2093
Alexander P Alimov
Horacio L Rilo
Kevin S Jones
Laura A Woollett
Ronald J Jandacek
W Todd Penberthy
P2860
P2888
P356
10.1186/1743-7075-5-23
P577
2008-08-27T00:00:00Z
P5875
P6179
1051593683