Proteolysis of the Ebola virus glycoproteins enhances virus binding and infectivity.
about
Lectin-dependent enhancement of Ebola virus infection via soluble and transmembrane C-type lectin receptorsSmall molecule inhibitors reveal Niemann-Pick C1 is essential for Ebola virus infectionIdentification of a broad-spectrum antiviral small molecule against severe acute respiratory syndrome coronavirus and Ebola, Hendra, and Nipah viruses by using a novel high-throughput screening assayEbola virus entry requires the host-programmed recognition of an intracellular receptorThe organisation of Ebola virus reveals a capacity for extensive, modular polyploidyEbolavirus is internalized into host cells via macropinocytosis in a viral glycoprotein-dependent mannerAntigenic subversion: a novel mechanism of host immune evasion by Ebola virusStructures and Mechanisms of Viral Membrane Fusion Proteins: Multiple Variations on a Common ThemeNeutralizing ebolavirus: structural insights into the envelope glycoprotein and antibodies targeted against itEbolavirus glycoprotein structure and mechanism of entryStructure of the Ebola virus glycoprotein bound to an antibody from a human survivorStructure of an Antibody in Complex with Its Mucin Domain Linear Epitope That Is Protective against Ebola VirusHost-Primed Ebola Virus GP Exposes a Hydrophobic NPC1 Receptor-Binding Pocket, Revealing a Target for Broadly Neutralizing AntibodiesEbola virus: A gap in drug design and discovery - experimental and computational perspective.Induction of Cell-Cell Fusion by Ebola Virus Glycoprotein: Low pH Is Not a TriggerSpatial localization of the Ebola virus glycoprotein mucin-like domain determined by cryo-electron tomography.A new player in the puzzle of filovirus entry.Cathepsin cleavage potentiates the Ebola virus glycoprotein to undergo a subsequent fusion-relevant conformational change.Cell adhesion-dependent membrane trafficking of a binding partner for the ebolavirus glycoprotein is a determinant of viral entryThe primed ebolavirus glycoprotein (19-kilodalton GP1,2): sequence and residues critical for host cell binding.Impact of spatial dispersion, evolution, and selection on Ebola Zaire Virus epidemic wavesThe identification, characterization and optimization of small molecule probes of cysteine proteases: experiences of the Penn Center for Molecular Discovery with cathepsin B and cathepsin L.Insulin degrading enzyme induces a conformational change in varicella-zoster virus gE, and enhances virus infectivity and stabilityBiochemical and structural characterization of cathepsin L-processed Ebola virus glycoprotein: implications for viral entry and immunogenicityIdentification of continuous human B-cell epitopes in the VP35, VP40, nucleoprotein and glycoprotein of Ebola virusDifferent potential of C-type lectin-mediated entry between Marburg virus strainsA small-molecule oxocarbazate inhibitor of human cathepsin L blocks severe acute respiratory syndrome and ebola pseudotype virus infection into human embryonic kidney 293T cells.Ebola virus glycoprotein needs an additional trigger, beyond proteolytic priming for membrane fusionTherapeutics for filovirus infection: traditional approaches and progress towards in silico drug design.Cathepsin B & L are not required for ebola virus replicationInhibition of Ebola virus entry by a C-peptide targeted to endosomes.Impact of Ebola mucin-like domain on antiglycoprotein antibody responses induced by Ebola virus-like particles.Differential requirements for clathrin endocytic pathway components in cellular entry by Ebola and Marburg glycoprotein pseudovirions.Protective mAbs and Cross-Reactive mAbs Raised by Immunization with Engineered Marburg Virus GPsInduction of ebolavirus cross-species immunity using retrovirus-like particles bearing the Ebola virus glycoprotein lacking the mucin-like domain.Critical role of leucine-valine change in distinct low pH requirements for membrane fusion between two related retrovirus envelopes.The role of antigen-presenting cells in filoviral hemorrhagic fever: gaps in current knowledge.Filoviruses require endosomal cysteine proteases for entry but exhibit distinct protease preferencesFilovirus entry into cells - new insights.Antibody-mediated neutralization of Ebola virus can occur by two distinct mechanisms.
P2860
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P2860
Proteolysis of the Ebola virus glycoproteins enhances virus binding and infectivity.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Proteolysis of the Ebola virus glycoproteins enhances virus binding and infectivity.
@en
type
label
Proteolysis of the Ebola virus glycoproteins enhances virus binding and infectivity.
@en
prefLabel
Proteolysis of the Ebola virus glycoproteins enhances virus binding and infectivity.
@en
P2860
P356
P1433
P1476
Proteolysis of the Ebola virus glycoproteins enhances virus binding and infectivity.
@en
P2093
Rachel L Kaletsky
P2860
P304
13378-13384
P356
10.1128/JVI.01170-07
P407
P577
2007-10-10T00:00:00Z