Mrc1 protects uncapped budding yeast telomeres from exonuclease EXO1.
about
Mrc1 and DNA polymerase epsilon function together in linking DNA replication and the S phase checkpointPolymerase epsilon is required to maintain replicative senescence.Distinct activities of exonuclease 1 and flap endonuclease 1 at telomeric g4 DNAA genetic screen for replication initiation defective (rid) mutants in Schizosaccharomyces pombeContinued DNA synthesis in replication checkpoint mutants leads to fork collapse.Pif1- and Exo1-dependent nucleases coordinate checkpoint activation following telomere uncapping.Checkpoint-dependent phosphorylation of Exo1 modulates the DNA damage responseGenome-wide screen reveals replication pathway for quasi-palindrome fragility dependent on homologous recombination.Binding of Multiple Rap1 Proteins Stimulates Chromosome Breakage Induction during DNA Replication.High rates of "unselected" aneuploidy and chromosome rearrangements in tel1 mec1 haploid yeast strainsSaccharomyces cerevisiae as a Model to Study Replicative Senescence Triggered by Telomere Shortening.DNA damage response at functional and dysfunctional telomeresMultiple functions of the S-phase checkpoint mediator.Molecular mechanisms involved in initiation of the DNA damage response.Genome-wide screen identifies pathways that govern GAA/TTC repeat fragility and expansions in dividing and nondividing yeast cells.Early telomerase inactivation accelerates aging independently of telomere length.Mrc1 marks early-firing origins and coordinates timing and efficiency of initiation in fission yeast.Dissection of Rad9 BRCT domain function in the mitotic checkpoint response to telomere uncapping.Early Loss of Telomerase Action in Yeast Creates a Dependence on the DNA Damage Response Adaptor Proteins.
P2860
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P2860
Mrc1 protects uncapped budding yeast telomeres from exonuclease EXO1.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
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2007年學術文章
@zh-hant
name
Mrc1 protects uncapped budding yeast telomeres from exonuclease EXO1.
@en
type
label
Mrc1 protects uncapped budding yeast telomeres from exonuclease EXO1.
@en
prefLabel
Mrc1 protects uncapped budding yeast telomeres from exonuclease EXO1.
@en
P2860
P1433
P1476
Mrc1 protects uncapped budding yeast telomeres from exonuclease EXO1.
@en
P2093
Avgi Tsolou
David Lydall
P2860
P304
P356
10.1016/J.DNAREP.2007.05.010
P577
2007-07-06T00:00:00Z