Tumor necrosis factor-related apoptosis-inducing ligand activates a lysosomal pathway of apoptosis that is regulated by Bcl-2 proteins. - Wikidata - wikimedia - TriplyDB

Tumor necrosis factor-related apoptosis-inducing ligand activates a lysosomal pathway of apoptosis that is regulated by Bcl-2 proteins.

Tumor necrosis factor-related apoptosis-inducing ligand activates a lysosomal pathway of apoptosis that is regulated by Bcl-2 proteins.

http://www.wikidata.org/entity/Q40096579

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The endolysosomal system in cell death and survival The lysosome: from waste bag to potential therapeutic target Cellular inhibitor of apoptosis (cIAP)-mediated ubiquitination of phosphofurin acidic cluster sorting protein 2 (PACS-2) negatively regulates tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) cytotoxicity Viral replication rate regulates clinical outcome and CD8 T cell responses during highly pathogenic H5N1 influenza virus infection in mice Continuous imaging of plasmon rulers in live cells reveals early-stage caspase-3 activation at the single-molecule level.Triptolide sensitizes pancreatic cancer cells to TRAIL-induced activation of the death receptor pathway Oxidative stress and autophagy in the regulation of lysosome-dependent neuron death.Hepatocyte death: a clear and present danger.miR-25 targets TNF-related apoptosis inducing ligand (TRAIL) death receptor-4 and promotes apoptosis resistance in cholangiocarcinoma Dysregulation of macrophage-secreted cathepsin B contributes to HIV-1-linked neuronal apoptosis.Nonesterified cholesterol content of lysosomes modulates susceptibility to oxidant-induced permeabilization.Caffeic acid phenethyl ester decreases cholangiocarcinoma growth by inhibition of NF-kappaB and induction of apoptosis.Artesunate activates mitochondrial apoptosis in breast cancer cells via iron-catalyzed lysosomal reactive oxygen species production The anti-tumour compound, RH1, causes mitochondria-mediated apoptosis by activating c-Jun N-terminal kinase.Eucommia ulmoides cortex, geniposide and aucubin regulate lipotoxicity through the inhibition of lysosomal BAX.The TRAIL to viral pathogenesis: the good, the bad and the ugly Camalexin-induced apoptosis in prostate cancer cells involves alterations of expression and activity of lysosomal protease cathepsin D.Cryptococcus neoformans-induced macrophage lysosome damage crucially contributes to fungal virulence.Combination of TRAIL with bortezomib shifted apoptotic signaling from DR4 to DR5 death receptor by selective internalization and degradation of DR4.Death receptor 5 signaling promotes hepatocyte lipoapoptosis Glycogen Synthase Kinase-3β and Caspase-2 Mediate Ceramide- and Etoposide-Induced Apoptosis by Regulating the Lysosomal-Mitochondrial Axis.Increased apoptosis in cancer cells in vitro and in vivo by ceramides in transferrin-modified liposomes.Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) protein-induced lysosomal translocation of proapoptotic effectors is mediated by phosphofurin acidic cluster sorting protein-2 (PACS-2)Autophagy and neuronal cell death in neurological disorders Low-density lipoprotein receptor-related protein 1 mediates α1-antitrypsin internalization in CD4+ T lymphocytes.PIG7 promotes leukemia cell chemosensitivity via lysosomal membrane permeabilization.Cellular and molecular mechanisms of liver injury.Targeting TNF-related apoptosis-inducing ligand (TRAIL) receptor by natural products as a potential therapeutic approach for cancer therapy Lysosomes in iron metabolism, ageing and apoptosis.Lysosomal serine protease CLN2 regulates tumor necrosis factor-alpha-mediated apoptosis in a Bid-dependent manner New derivatives of the antimalarial drug Pyrimethamine in the control of melanoma tumor growth: an in vitro and in vivo study.Death by committee: organellar trafficking and communication in apoptosis.Apoptosis and necrosis in the liver Lysosomes as "suicide bags" in cell death: myth or reality?Regulation of apoptosis-associated lysosomal membrane permeabilization.Non-canonical kinase signaling by the death ligand TRAIL in cancer cells: discord in the death receptor family.Intimacy and a deadly feud: the interplay of autophagy and apoptosis mediated by amino acids.The role of lysosome in cell death regulation.Enzymatically active cathepsin D sensitizes breast carcinoma cells to TRAIL.Calpain, Atg5 and Bak play important roles in the crosstalk between apoptosis and autophagy induced by influx of extracellular calcium.

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P2860

Tumor necrosis factor-related apoptosis-inducing ligand activates a lysosomal pathway of apoptosis that is regulated by Bcl-2 proteins.

http://www.wikidata.org/entity/Q40096579

description

2007 nî lūn-bûn

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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2007年论文

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2007年论文

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name

Tumor necrosis factor-related ...... s regulated by Bcl-2 proteins.

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type

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Tumor necrosis factor-related ...... s regulated by Bcl-2 proteins.

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Tumor necrosis factor-related ...... s regulated by Bcl-2 proteins.

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Journal of Biological Chemistry

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Tumor necrosis factor-related ...... s regulated by Bcl-2 proteins.

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P2093

M Eugenia Guicciardi

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Nathan W Werneburg

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Scott H Kaufmann

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Steve F Bronk

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P2860

Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function

Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak

Conformation of the Bax C-terminus regulates subcellular location and cell death

Inhibition of dsRNA-induced signaling in hepatitis C virus-infected cells by NS3 protease-dependent and -independent mechanisms

JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis

Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis

Movement of Bax from the cytosol to mitochondria during apoptosis

Up-regulation of c-Jun-NH2-kinase pathway contributes to the induction of mitochondria-mediated apoptosis by alpha-tocopheryl succinate in human prostate cancer cells.

From receptors to stress-activated MAP kinases

Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation

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28960-28970

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scholarly article

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10.1074/JBC.M705671200

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39

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282

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Gregory J Gores

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2007-08-08T00:00:00Z

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6152345

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17686764

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