HPat provides a link between deadenylation and decapping in metazoa.
about
Distinct functions of maternal and somatic Pat1 protein paralogsThe human Pat1b protein: a novel mRNA deadenylation factor identified by a new immunoprecipitation techniqueThe C-terminal alpha-alpha superhelix of Pat is required for mRNA decapping in metazoaHuman Pat1b connects deadenylation with mRNA decapping and controls the assembly of processing bodiesNew insights into decapping enzymes and selective mRNA decayProteins involved in the degradation of cytoplasmic mRNA in the major eukaryotic model systemsThe structural basis of Edc3- and Scd6-mediated activation of the Dcp1:Dcp2 mRNA decapping complexStructural analysis of the yeast Dhh1-Pat1 complex reveals how Dhh1 engages Pat1, Edc3 and RNA in mutually exclusive interactionsA direct interaction between DCP1 and XRN1 couples mRNA decapping to 5' exonucleolytic degradationThe C-Terminal Domain from S. cerevisiae Pat1 Displays Two Conserved Regions Involved in Decapping Factor RecruitmentPat1 contributes to the RNA binding activity of the Lsm1-7-Pat1 complex.Novel roles of the multi-functional CCR4-NOT complex in post-transcriptional regulation.Cytoplasmic mRNP granules at a glanceDcp1 links coactivators of mRNA decapping to Dcp2 by proline recognition.The complexity of miRNA-mediated repressionHPat a decapping activator interacting with the miRNA effector complex.The mRNA decay factor PAT1 functions in a pathway including MAP kinase 4 and immune receptor SUMM2.CUP promotes deadenylation and inhibits decapping of mRNA targets.RNA-related nuclear functions of human Pat1b, the P-body mRNA decay factor.General and MicroRNA-Mediated mRNA Degradation Occurs on Ribosome Complexes in Drosophila Cells.P-body assembly requires DDX6 repression complexes rather than decay or Ataxin2/2L complexes.Nuclear LSm8 affects number of cytoplasmic processing bodies via controlling cellular distribution of Like-Sm proteins.The conserved P body component HPat/Pat1 negatively regulates synaptic terminal growth at the larval Drosophila neuromuscular junction.Arabidopsis thaliana LSM proteins function in mRNA splicing and degradation.Uridylation prevents 3' trimming of oligoadenylated mRNAsA CAF40-binding motif facilitates recruitment of the CCR4-NOT complex to mRNAs targeted by Drosophila Roquin.Structural and functional control of the eukaryotic mRNA decapping machinery.The role of disordered protein regions in the assembly of decapping complexes and RNP granules.Interrelations between translation and general mRNA degradation in yeast.Dual RNA Processing Roles of Pat1b via Cytoplasmic Lsm1-7 and Nuclear Lsm2-8 Complexes.Translational repression of the Drosophila nanos mRNA involves the RNA helicase Belle and RNA coating by Me31B and Trailer hitch.Roles of mRNA fate modulators Dhh1 and Pat1 in TNRC6-dependent gene silencing recapitulated in yeast.An mRNA decapping mutant deficient in P body assembly limits mRNA stabilization in response to osmotic stress.Human DDX6 effects miRNA-mediated gene silencing via direct binding to CNOT1.Role of Rck-Pat1b binding in assembly of processing-bodies.A unique surface on Pat1 C-terminal domain directly interacts with Dcp2 decapping enzyme and Xrn1 5'-3' mRNA exonuclease in yeast.Polysomes, stress granules and processing bodies: a dynamic triumvirate controlling cytoplasmic mRNA fate and function.Female Infertility Caused by Mutations in the Oocyte-Specific Translational Repressor PATL2.ME31B globally represses maternal mRNAs by two distinct mechanisms during the Drosophila maternal-to-zygotic transition.Involvement of fission yeast Pdc2 in RNA degradation and P-body function.
P2860
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P2860
HPat provides a link between deadenylation and decapping in metazoa.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
HPat provides a link between deadenylation and decapping in metazoa.
@en
type
label
HPat provides a link between deadenylation and decapping in metazoa.
@en
prefLabel
HPat provides a link between deadenylation and decapping in metazoa.
@en
P2093
P2860
P50
P356
P1476
HPat provides a link between deadenylation and decapping in metazoa.
@en
P2093
Felix Tritschler
Gabrielle Haas
Tadashi Nishihara
P2860
P304
P356
10.1083/JCB.200910141
P407
P577
2010-04-01T00:00:00Z