Mechanism of action of the microtubule-targeted antimitotic depsipeptide tasidotin (formerly ILX651) and its major metabolite tasidotin C-carboxylate.

Mechanism of action of the microtubule-targeted antimitotic depsipeptide tasidotin (formerly ILX651) and its major metabolite tasidotin C-carboxylate.

Item
http://www.wikidata.org/entity/Q40144522
Tubulin-interactive natural products as anticancer agentsStabilizing versus destabilizing the microtubules: a double-edge sword for an effective cancer treatment option?Marine Mollusk-Derived Agents with Antiproliferative Activity as Promising Anticancer Agents to Overcome Chemotherapy Resistance.Bioactive natural products from Papua New Guinea marine sponges.Epigenetic therapy for breast cancer.Intracellular activation and deactivation of tasidotin, an analog of dolastatin 15: correlation with cytotoxicityRegulation of microtubule dynamic instability in vitro by differentially phosphorylated stathmin.Anticancer agent-based marine natural products and related compounds.Recent developments in therapeutic applications of Cyanobacteria.Targeting HER2-positive cancer with dolastatin 15 derivatives conjugated to trastuzumab, novel antibody-drug conjugates.TACC3 protein regulates microtubule nucleation by affecting γ-tubulin ring complexes.Pharmacokinetics in mice implanted with xenografted tumors after intravenous administration of tasidotin (ILX651) or its carboxylate metabolite.A flexible asymmetric approach to methyl 5-alkyltetramates and its application in the synthesis of cytotoxic marine natural product belamide A.
P2860

Mechanism of action of the microtubule-targeted antimitotic depsipeptide tasidotin (formerly ILX651) and its major metabolite tasidotin C-carboxylate.

Item
http://www.wikidata.org/entity/Q40144522
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Mechanism of action of the mic ...... olite tasidotin C-carboxylate.
@en
type
label
Mechanism of action of the mic ...... olite tasidotin C-carboxylate.
@en
prefLabel
Mechanism of action of the mic ...... olite tasidotin C-carboxylate.
@en
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P356
P1433
P1476
Mechanism of action of the mic ...... bolite tasidotin C-carboxylate
@en
P2093
P304
P31
P356
10.1158/0008-5472.CAN-06-3065
P407
P433
P478
P50
P577
P5875
P698