Intracellular activation and deactivation of tasidotin, an analog of dolastatin 15: correlation with cytotoxicity
about
Stabilizing versus destabilizing the microtubules: a double-edge sword for an effective cancer treatment option?Marine Mollusk-Derived Agents with Antiproliferative Activity as Promising Anticancer Agents to Overcome Chemotherapy Resistance.Marine sponge-derived sipholane triterpenoids reverse P-glycoprotein (ABCB1)-mediated multidrug resistance in cancer cellsCurrent status on marine products with reversal effect on cancer multidrug resistance.Tubulin targets in the pathobiology and therapy of glioblastoma multiforme. I. Class III beta-tubulin.Issues about the physiological functions of prolyl oligopeptidase based on its discordant spatial association with substrates and inconsistencies among mRNA, protein levels, and enzymatic activityTargeting HER2-positive cancer with dolastatin 15 derivatives conjugated to trastuzumab, novel antibody-drug conjugates.(-)-Rhazinilam and the diphenylpyridazinone NSC 613241: Two compounds inducing the formation of morphologically similar tubulin spirals but binding apparently to two distinct sites on tubulin.New compounds identified through in silico approaches reduce the α-synuclein expression by inhibiting prolyl oligopeptidase in vitro.Marine Peptides and Proteins with Cytotoxic and Antitumoral Properties
P2860
Q26781365-C3A7EB68-155E-491B-9B93-EFEF471501F3Q33834080-088B6158-B83D-432F-94F0-C9C8EB395CE9Q34166391-3B0000E7-33D5-4A53-B284-72D181FFD9D9Q36395803-C36B6378-7645-480B-BAFF-1CB62A3104A2Q37570220-73D7647F-77D6-4574-B6A6-BD90146BE6E2Q37581327-5049D32A-A508-4E8D-8C2D-80E5FD9DAD11Q39310345-8AA11C6F-D2E9-44B5-AA27-11F298A5AC2AQ39677771-AA4AE4DD-03BF-4E5C-9874-D3C7FF40188EQ41544270-F7528F8B-D550-4E73-A9E2-21DDB5D31184Q58035054-09EE676F-10B1-4E39-ACD2-4E119CE8F966
P2860
Intracellular activation and deactivation of tasidotin, an analog of dolastatin 15: correlation with cytotoxicity
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 16 October 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Intracellular activation and d ...... correlation with cytotoxicity
@en
Intracellular activation and d ...... correlation with cytotoxicity.
@nl
type
label
Intracellular activation and d ...... correlation with cytotoxicity
@en
Intracellular activation and d ...... correlation with cytotoxicity.
@nl
prefLabel
Intracellular activation and d ...... correlation with cytotoxicity
@en
Intracellular activation and d ...... correlation with cytotoxicity.
@nl
P2093
P2860
P356
P1476
Intracellular activation and d ...... correlation with cytotoxicity
@en
P2093
Ernest Hamel
George R Pettit
Michael C Edler
Peter L Bonate
Richard F Ludueña
Terry D Copeland
P2860
P304
P356
10.1124/MOL.108.051110
P577
2008-10-16T00:00:00Z