Anti-desmoglein 3 (Dsg3) monoclonal antibodies deplete desmosomes of Dsg3 and differ in their Dsg3-depleting activities related to pathogenicity.
about
Desmosomes in acquired diseaseDesmosome assembly and disassembly are membrane raft-dependentPemphigus vulgaris IgG-induced desmoglein-3 endocytosis and desmosomal disassembly are mediated by a clathrin- and dynamin-independent mechanismEGFR and ADAMs cooperate to regulate shedding and endocytic trafficking of the desmosomal cadherin desmoglein 2.Peptides Targeting the Desmoglein 3 Adhesive Interface Prevent Autoantibody-induced Acantholysis in Pemphigus.Adducin is required for desmosomal cohesion in keratinocytes.Loss of the desmosomal protein perp enhances the phenotypic effects of pemphigus vulgaris autoantibodies.Signaling dependent and independent mechanisms in pemphigus vulgaris blister formationStructure, function, and regulation of desmosomes.Cell-cell adhesions and cell contractility are upregulated upon desmosome disruptionThe extent of desmoglein 3 depletion in pemphigus vulgaris is dependent on Ca(2+)-induced differentiation: a role in suprabasal epidermal skin splitting?The desmosome and pemphigus.Involvement of the apoptotic mechanism in pemphigus foliaceus autoimmune injury of the skin.Disruption of desmosome assembly by monovalent human pemphigus vulgaris monoclonal antibodies.Desmosomes: adhesive strength and signalling in health and disease.Cell-cell connectivity: desmosomes and disease.Urban legends: pemphigus vulgaris.Desmosomal adhesion and pemphigus vulgaris: the first half of the story.p38 MAPK Signaling in Pemphigus: Implications for Skin AutoimmunityDesmosomal adhesion in vivo.Desmosomal cadherins and signaling: lessons from autoimmune disease.Hyper-adhesion: a unique property of desmosomes.150(th) anniversary series: Desmosomes and autoimmune disease, perspective of dynamic desmosome remodeling and its impairments in pemphigus.Deregulation of PERK in the autoimmune disease pemphigus vulgaris occurs via IgG-independent mechanisms.Protective endogenous cyclic adenosine 5'-monophosphate signaling triggered by pemphigus autoantibodies.Desmosome disassembly in response to pemphigus vulgaris IgG occurs in distinct phases and can be reversed by expression of exogenous Dsg3Nuclear magnetic resonance titration of the interaction between pemphigus vulgaris autoantibodies and REWVKFAKPCRE, a therapeutic desmoglein 3 peptide.An adult passive transfer mouse model to study desmoglein 3 signaling in pemphigus vulgaris.Experimental human cell and tissue models of pemphigus.Non-pathogenic pemphigus foliaceus (PF) IgG acts synergistically with a directly pathogenic PF IgG to increase blistering by p38MAPK-dependent desmoglein 1 clustering.Desmosomes in vivoCell-Cell Junctions Organize Structural and Signaling Networks.Pemphigus-A Disease of Desmosome Dysfunction Caused by Multiple Mechanisms.Keratins Regulate p38MAPK-Dependent Desmoglein Binding Properties in Pemphigus.
P2860
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P2860
Anti-desmoglein 3 (Dsg3) monoclonal antibodies deplete desmosomes of Dsg3 and differ in their Dsg3-depleting activities related to pathogenicity.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Anti-desmoglein 3 (Dsg3) monoc ...... ties related to pathogenicity.
@en
type
label
Anti-desmoglein 3 (Dsg3) monoc ...... ties related to pathogenicity.
@en
prefLabel
Anti-desmoglein 3 (Dsg3) monoc ...... ties related to pathogenicity.
@en
P2093
P2860
P356
P1476
Anti-desmoglein 3 (Dsg3) monoc ...... ties related to pathogenicity.
@en
P2093
Kazuyuki Tsunoda
Yasuo Kitajima
Yukari Yamamoto
Yumi Aoyama
P2860
P304
17866-17876
P356
10.1074/JBC.M607963200
P407
P577
2007-04-11T00:00:00Z