Analysis of CD95 threshold signaling: triggering of CD95 (FAS/APO-1) at low concentrations primarily results in survival signaling. - Wikidata - wikimedia - TriplyDB

Analysis of CD95 threshold signaling: triggering of CD95 (FAS/APO-1) at low concentrations primarily results in survival signaling.

Analysis of CD95 threshold signaling: triggering of CD95 (FAS/APO-1) at low concentrations primarily results in survival signaling.

http://www.wikidata.org/entity/Q40161643

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Modulation of the CD95-induced apoptosis: the role of CD95 N-glycosylation The Fas-FADD death domain complex structure unravels signalling by receptor clustering CD95 promotes tumour growth FLIP the Switch: Regulation of Apoptosis and Necroptosis by cFLIP Regulation of CD95/Fas signaling at the DISC Molecular architecture of the DED chains at the DISC: regulation of procaspase-8 activation by short DED proteins c-FLIP and procaspase-8 prodomain ON/OFF and beyond--a boolean model of apoptosis Mathematical modelling of cell-fate decision in response to death receptor engagement Steady state detection of chemical reaction networks using a simplified analytical method The death effector domains of caspase-8 induce terminal differentiation.Modeling system states in liver cells: survival, apoptosis and their modifications in response to viral infection Modulation of TRAIL resistance in colon carcinoma cells: different contributions of DR4 and DR5.A death effector domain chain DISC model reveals a crucial role for caspase-8 chain assembly in mediating apoptotic cell death.Model-based dissection of CD95 signaling dynamics reveals both a pro- and antiapoptotic role of c-FLIPL.Measuring and modeling apoptosis in single cells.Lyapunov exponents and phase diagrams reveal multi-factorial control over TRAIL-induced apoptosis.Death receptor 6 (DR6) is required for mouse B16 tumor angiogenesis via the NF-κB, P38 MAPK and STAT3 pathways.Cells surviving fractional killing by TRAIL exhibit transient but sustainable resistance and inflammatory phenotypes.Fas expression is downregulated in gastric cancer.Life in the Fas lane: differential outcomes of Fas signaling.Mathematical modeling of apoptosis.Harnessing system models of cell death signalling for cytotoxic chemotherapy: towards personalised medicine approaches?Systems biology of death receptor networks: live and let die.Surviving apoptosis: life-death signaling in single cells.Cell death-independent activities of the death receptors CD95, TRAILR1, and TRAILR2.Caspase-8 activity has an essential role in CD95/Fas-mediated MAPK activation Systems analysis of cancer cell heterogeneity in caspase-dependent apoptosis subsequent to mitochondrial outer membrane permeabilization.Signaling active CD95 receptor molecules trigger co-translocation of inactive CD95 molecules into lipid rafts Modeling reveals that dynamic regulation of c-FLIP levels determines cell-to-cell distribution of CD95-mediated apoptosis.A20 Curtails Primary but Augments Secondary CD8+ T Cell Responses in Intracellular Bacterial Infection.Parameter identification using stochastic simulations reveals a robustness in CD95 apoptotic response.Dynamics within the CD95 death-inducing signaling complex decide life and death of cells.Pro- and anti-apoptotic CD95 signaling in T cells.A Novel High-Throughput Technique for Identifying Monoclonal Antibodies Capable of Death Receptor Induced Apoptosis.Apoptotic potential of Fas-associated death domain on regulation of cell death regulatory protein cFLIP and death receptor mediated apoptosis in HEK 293T cells.Modulation of CD4+ T-cell activation by CD95 co-stimulation.The chains of death: a new view on caspase-8 activation at the DISC.Depletion of the receptor for advanced glycation end products (RAGE) sensitizes towards apoptosis via p53 and p73 posttranslational regulation.Analysis of a mathematical model of apoptosis: individual differences and malfunction in programmed cell death.Real time analysis of tumor necrosis factor-related apoptosis-inducing ligand/cycloheximide-induced caspase activities during apoptosis initiation.

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P2860

Analysis of CD95 threshold signaling: triggering of CD95 (FAS/APO-1) at low concentrations primarily results in survival signaling.

http://www.wikidata.org/entity/Q40161643

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2007 nî lūn-bûn

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2007年の論文

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年學術文章

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2007年學術文章

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2007年學術文章

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Analysis of CD95 threshold sig ...... results in survival signaling.

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Analysis of CD95 threshold sig ...... results in survival signaling.

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Analysis of CD95 threshold sig ...... results in survival signaling.

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Journal of Biological Chemistry

P1476

Analysis of CD95 threshold sig ...... results in survival signaling.

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P2093

Alexander Golks

http://www.w3.org/2001/XMLSchema#string

Dagmar Riess

http://www.w3.org/2001/XMLSchema#string

Inna N Lavrik

http://www.w3.org/2001/XMLSchema#string

Martin Bentele

http://www.w3.org/2001/XMLSchema#string

Peter H Krammer

http://www.w3.org/2001/XMLSchema#string

Roland Eils

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P2860

CD95's deadly mission in the immune system

Cellular FLICE-inhibitory protein splice variants inhibit different steps of caspase-8 activation at the CD95 death-inducing signaling complex

FLICE is activated by association with the CD95 death-inducing signaling complex (DISC).

Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family

Apoptosis by death factor

The death receptor antagonist FAIM promotes neurite outgrowth by a mechanism that depends on ERK and NF-kapp B signaling

The CD95 (APO-1/Fas) and the TRAIL (APO-2L) apoptosis systems.

Regulation of death receptor-mediated apoptosis pathways.

Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c.

Induction of apoptosis and activation of NF-kappaB by CD95 require different signalling thresholds.

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13664-13671

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scholarly article

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10.1074/JBC.M700434200

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18

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282

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17347143

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