Ketolide antimicrobial activity persists after disruption of interactions with domain II of 23S rRNA.
about
Binding and action of CEM-101, a new fluoroketolide antibiotic that inhibits protein synthesisStructures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug actionThe bacterial ribosome as a target for antibiotics23S rRNA base pair 2057-2611 determines ketolide susceptibility and fitness cost of the macrolide resistance mutation 2058A-->G.Macrolide- and telithromycin-resistant Streptococcus pyogenes, Belgium, 1999-2003The chemistry of peptidyltransferase center-targeted antibiotics: enzymatic resistance and approaches to countering resistance.Inhibition of protein synthesis on the ribosome by tildipirosin compared with other veterinary macrolidesMacrolide resistance mechanisms in Enterobacteriaceae: Focus on azithromycin.Mycoplasma bovis isolates from dairy calves in Japan have less susceptibility than a reference strain to all approved macrolides associated with a point mutation (G748A) combined with multiple species-specific nucleotide alterations in 23S rRNA.Methylation of 23S rRNA nucleotide G748 by RlmAII methyltransferase renders Streptococcus pneumoniae telithromycin susceptible.Investigating the entire course of telithromycin binding to Escherichia coli ribosomes.Pharmacodynamic activity of telithromycin at simulated clinically achievable free-drug concentrations in serum and epithelial lining fluid against efflux (mefE)-producing macrolide-resistant Streptococcus pneumoniae for which telithromycin MICs vary
P2860
Q24606228-B8852760-F349-4E98-BB90-30639DE7FA56Q27664697-63E7F9A9-6A9E-45DC-AEEF-732162E42F20Q28279726-3420FD93-AF96-4314-805B-9958C067EB4CQ33935053-27957CF3-5785-4F6D-AC26-653E6156E781Q36009330-E86BF9A3-9EA3-44B7-A119-1F72EF33FF83Q37972308-06732B19-38DE-4B4F-9BA3-AB618F0DEF05Q38322265-CACB3C81-687B-4392-92C0-B0D66087B344Q38804355-2610A8A4-93DF-4858-A1FD-FA635B3F4FE6Q40212926-D11C7E13-BED3-40C5-9A53-8125F449C01FQ41791211-3BDE3698-5C43-4CF8-A3EB-708835A7097CQ42057254-55A34843-9E35-4AD8-8455-660640300649Q42252396-01501239-49B6-4A13-94DC-F5BFF82ABF13
P2860
Ketolide antimicrobial activity persists after disruption of interactions with domain II of 23S rRNA.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Ketolide antimicrobial activit ...... ns with domain II of 23S rRNA.
@en
type
label
Ketolide antimicrobial activit ...... ns with domain II of 23S rRNA.
@en
prefLabel
Ketolide antimicrobial activit ...... ns with domain II of 23S rRNA.
@en
P2860
P50
P1476
Ketolide antimicrobial activit ...... ns with domain II of 23S rRNA.
@en
P2093
Jacob Poehlsgaard
Lene Jakobsen
P2860
P304
P356
10.1128/AAC.48.10.3677-3683.2004
P407
P577
2004-10-01T00:00:00Z