Bidirectional shifts of TRPM8 channel gating by temperature and chemical agents modulate the cold sensitivity of mammalian thermoreceptors.
about
TRP channel-associated factors are a novel protein family that regulates TRPM8 trafficking and activity.Roles of TRPM8 Ion Channels in Cancer: Proliferation, Survival, and InvasionTRPM8, a versatile channel in human spermPharmacological blockade of TRPM8 ion channels alters cold and cold pain responses in miceThe Concise Guide to PHARMACOLOGY 2013/14: ion channelsTRPV1 and TRPA1 mediate peripheral nitric oxide-induced nociception in mice.Sex differences in mouse Transient Receptor Potential Cation Channel, Subfamily M, Member 8 expressing trigeminal ganglion neurons.Odors activate dual pathways, a TRPC2 and a AA-dependent pathway, in mouse vomeronasal neurons.Topical application of L-menthol induces heat analgesia, mechanical allodynia, and a biphasic effect on cold sensitivity in rats.Sensing hot and cold with TRP channels.TRPM8 ion channels differentially modulate proliferation and cell cycle distribution of normal and cancer prostate cellsThe influence of cold temperature on cellular excitability of hippocampal networksVoltage- and cold-dependent gating of single TRPM8 ion channels.TRPM8 and Nav1.8 sodium channels are required for transthyretin-induced calcium influx in growth cones of small-diameter TrkA-positive sensory neurons.Scraping through the ice: uncovering the role of TRPM8 in cold transductionShort isoforms of the cold receptor TRPM8 inhibit channel gating by mimicking heat action rather than chemical inhibitors.TRPM8-Dependent Dynamic Response in a Mathematical Model of Cold ThermoreceptorRegulation of TRPM8 channel activityChemosensory properties of the trigeminal system.Thermosensitive transient receptor potential (TRP) channel agonists and their role in mechanical, thermal and nociceptive sensations as assessed using animal models.CRISP1 as a novel CatSper regulator that modulates sperm motility and orientation during fertilization.TRPM8 ion channel is aberrantly expressed and required for preventing replicative senescence in pancreatic adenocarcinoma: potential role of TRPM8 as a biomarker and targetPirt functions as an endogenous regulator of TRPM8.Molecular and cellular limits to somatosensory specificity.Complex N-glycosylation stabilizes surface expression of transient receptor potential melastatin 4b protein.Pharmacology of transient receptor potential melastatin channels in the vasculatureTargeting TRPC6 channels in oesophageal carcinoma growth.The thermo-TRP ion channel family: properties and therapeutic implications.A cool channel in cold transduction.Neurodegeneration in familial amyloidotic polyneuropathy.Current perspectives on the modulation of thermo-TRP channels: new advances and therapeutic implications.New strategies to develop novel pain therapies: addressing thermoreceptors from different points of view.Trafficking of ThermoTRP Channels.N-glycosylation of the transient receptor potential melastatin 8 channel is altered in pancreatic cancer cells.N-glycosylation of TRPM8 ion channels modulates temperature sensitivity of cold thermoreceptor neurons.Essential role of TRPC6 channels in G2/M phase transition and development of human glioma.Modulation of the cold-activated cation channel TRPM8 by surface charge screening.Differential role of the menthol-binding residue Y745 in the antagonism of thermally gated TRPM8 channels.Glycolytic metabolite methylglyoxal inhibits cold and menthol activation of the transient receptor potential melastatin type 8 channel.Synthesis, high-throughput screening and pharmacological characterization of β-lactam derivatives as TRPM8 antagonists.
P2860
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P2860
Bidirectional shifts of TRPM8 channel gating by temperature and chemical agents modulate the cold sensitivity of mammalian thermoreceptors.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Bidirectional shifts of TRPM8 ...... of mammalian thermoreceptors.
@en
type
label
Bidirectional shifts of TRPM8 ...... of mammalian thermoreceptors.
@en
prefLabel
Bidirectional shifts of TRPM8 ...... of mammalian thermoreceptors.
@en
P2093
P2860
P1476
Bidirectional shifts of TRPM8 ...... y of mammalian thermoreceptors
@en
P2093
Annika Mälkiä
Carlos Belmonte
Elvira de la Peña
María Valero
Rodolfo Madrid
Victor Meseguer
P2860
P304
P356
10.1113/JPHYSIOL.2006.123059
P407
P50
P577
2007-02-22T00:00:00Z