Polymerizing actin fibers position integrins primed to probe for adhesion sites.
about
The cell surface environment for pathogen recognition and entryAnalysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturationIntegrins β1 and β3 exhibit distinct dynamic nanoscale organizations inside focal adhesionsMyocilin, a glaucoma-associated protein, promotes cell migration through activation of integrin-focal adhesion kinase-serine/threonine kinase signaling pathwayThe Regulation of Cellular Responses to Mechanical Cues by Rho GTPasesFilopodia and adhesion in cancer cell motilityThe development of a novel high throughput computational tool for studying individual and collective cellular migrationProperties of the force exerted by filopodia and lamellipodia and the involvement of cytoskeletal componentsChanges in single-molecule integrin dynamics linked to local cellular behavior.PCP Signaling between Migrating Neurons and their Planar-Polarized Neuroepithelial Environment Controls Filopodial Dynamics and Directional MigrationNudel and FAK as antagonizing strength modulators of nascent adhesions through paxillinSubstrate engagement of integrins α5β1 and αvβ3 is necessary, but not sufficient, for high directional persistence in migration on fibronectinCreatine kinase-mediated ATP supply fuels actin-based events in phagocytosisVinculin controls talin engagement with the actomyosin machinery.Maturation of filopodia shaft adhesions is upregulated by local cycles of lamellipodia advancements and retractionsLocal ATP generation by brain-type creatine kinase (CK-B) facilitates cell motilityTwo distinct filopodia populations at the growth cone allow to sense nanotopographical extracellular matrix cues to guide neurite outgrowthRole of the WASP and WAVE family proteins in breast cancer invasion and metastasisβ1 integrins regulate fibroblast chemotaxis through control of N-WASP stability.Rac1 is deactivated at integrin activation sites through an IQGAP1-filamin-A-RacGAP1 pathway.Actin and alpha-actinin orchestrate the assembly and maturation of nascent adhesions in a myosin II motor-independent manner.A RIAM/lamellipodin-talin-integrin complex forms the tip of sticky fingers that guide cell migrationIntegrin-associated complexes form hierarchically with variable stoichiometry in nascent adhesionsPAK-PIX interactions regulate adhesion dynamics and membrane protrusion to control neurite outgrowth.Integrins in cell migrationAdhesion dynamics at a glance.The serine/threonine kinase Par1b regulates epithelial lumen polarity via IRSp53-mediated cell-ECM signaling.Integrins in cell migration--the actin connection.Determination of hierarchical relationship of Src and Rac at subcellular locations with FRET biosensors.Talin depletion reveals independence of initial cell spreading from integrin activation and traction.R-Ras regulates beta1-integrin trafficking via effects on membrane ruffling and endocytosis.The actin-bundling protein palladin is an Akt1-specific substrate that regulates breast cancer cell migrationZyxin-mediated actin assembly is required for efficient wound closure.Protein 4.1R regulates cell adhesion, spreading, migration and motility of mouse keratinocytes by modulating surface expression of beta1 integrin.Involvement of actin polymerization in podosome dynamics.Rac1 recruitment to the archipelago structure of the focal adhesion through the fluid membrane as revealed by single-molecule analysisSpatial proteomic and phospho-proteomic organization in three prototypical cell migration modes.F-actin bundles direct the initiation and orientation of lamellipodia through adhesion-based signaling.Live-cell photoactivated localization microscopy of nanoscale adhesion dynamics.Structural and mechanical functions of integrins.
P2860
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P2860
Polymerizing actin fibers position integrins primed to probe for adhesion sites.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Polymerizing actin fibers position integrins primed to probe for adhesion sites.
@en
type
label
Polymerizing actin fibers position integrins primed to probe for adhesion sites.
@en
prefLabel
Polymerizing actin fibers position integrins primed to probe for adhesion sites.
@en
P356
P1433
P1476
Polymerizing actin fibers position integrins primed to probe for adhesion sites.
@en
P2093
Catherine G Galbraith
James A Galbraith
P304
P356
10.1126/SCIENCE.1137904
P407
P577
2007-02-01T00:00:00Z