Juxtamembrane-type c-kit gene mutation found in aggressive systemic mastocytosis induces imatinib-resistant constitutive KIT activation.
about
Germline mutations of KIT in gastrointestinal stromal tumor (GIST) and mastocytosisMutations in the c-Kit gene disrupt mitogen-activated protein kinase signaling during tumor development in adenoid cystic carcinoma of the salivary glandsRecent advances in the understanding of mastocytosis: the role of KIT mutations.Mastocytosis: a mutated KIT receptor induced myeloproliferative disorderClinical implications of mutational analysis in gastrointestinal stromal tumours.Advanced systemic mastocytosis: the impact of KIT mutations in diagnosis, treatment, and progressionMolecular drug targets in myeloproliferative neoplasms: mutant ABL1, JAK2, MPL, KIT, PDGFRA, PDGFRB and FGFR1.Systemic mastocytosis with skeletal involvement: a case report and review of the literature.Oncogene mutational profile in nasopharyngeal carcinoma.Advances and controversies in the diagnosis, pathogenesis, and treatment of systemic mastocytosis.Familial gastrointestinal stromal tumor syndrome: report of 2 cases with KIT exon 11 mutation.Imatinib in systemic mastocytosis: a phase IV clinical trial in patients lacking exon 17 KIT mutations and review of the literature.Selective RNAi-mediated inhibition of mutated c-kit.
P2860
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P2860
Juxtamembrane-type c-kit gene mutation found in aggressive systemic mastocytosis induces imatinib-resistant constitutive KIT activation.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Juxtamembrane-type c-kit gene ...... t constitutive KIT activation.
@en
type
label
Juxtamembrane-type c-kit gene ...... t constitutive KIT activation.
@en
prefLabel
Juxtamembrane-type c-kit gene ...... t constitutive KIT activation.
@en
P2860
P1476
Juxtamembrane-type c-kit gene ...... t constitutive KIT activation.
@en
P2093
Nami Nakagomi
Seiichi Hirota
P2860
P2888
P304
P356
10.1038/LABINVEST.3700524
P577
2007-01-29T00:00:00Z
P5875
P6179
1051955358