A hidden oncogenic positive feedback loop caused by crosstalk between Wnt and ERK pathways.
about
DIPSBC--data integration platform for systems biology collaborationsThe smallest chemical reaction system with bistabilityStructure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive reviewSelection on Network Dynamics Drives Differential Rates of Protein Domain EvolutionRobustness portraits of diverse biological networks conserved despite order-of-magnitude parameter uncertainty.Multiscale modeling of tumor growth induced by circadian rhythm disruption in epithelial tissue.Extended analyses of the Wnt/beta-catenin pathway: robustness and oscillatory behaviour.Using chemical organization theory for model checking.Dynamics and evolution of β-catenin-dependent Wnt signaling revealed through massively parallel clonogenic screening.Analysis of Wnt signaling β-catenin spatial dynamics in HEK293T cells.Predicting mechanism of biphasic growth factor action on tumor growth using a multi-species model with feedback control.Modelling spatially regulated beta-catenin dynamics and invasion in intestinal crypts.Musashi1 regulates breast tumor cell proliferation and is a prognostic indicator of poor survival.PSExplorer: whole parameter space exploration for molecular signaling pathway dynamicsWnt signalling pathway parameters for mammalian cellsA variational approach to parameter estimation in ordinary differential equationsElucidating the sources of β-catenin dynamics in human neural progenitor cellsFunctional roles of multiple feedback loops in extracellular signal-regulated kinase and Wnt signaling pathways that regulate epithelial-mesenchymal transition.Ras regulates SCF(β-TrCP) protein activity and specificity via its effector protein NORE1A.Src family kinase oncogenic potential and pathways in prostate cancer as revealed by AZD0530.Computational modeling of mammalian signaling networks.Computational modeling of the interplay between cadherin-mediated cell adhesion and Wnt signaling pathwayInhibition of ERK1/2 down-regulates the Hippo/YAP signaling pathway in human NSCLC cells.Basic fibroblast growth factor inhibits osteogenic differentiation of stem cells from human exfoliated deciduous teeth through ERK signaling.A functional connectome: regulation of Wnt/TCF-dependent transcription by pairs of pathway activators.The role of the Hes1 crosstalk hub in Notch-Wnt interactions of the intestinal crypt.Metastasis-associated protein 1 short form stimulates Wnt1 pathway in mammary epithelial and cancer cellsRegulation of Wnt4 in chronic obstructive pulmonary disease.Inhibition of peroxisome proliferator-activated receptor gamma increases estrogen receptor-dependent tumor specification.From individual Wnt pathways towards a Wnt signalling network.Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.Specificity and robustness of the mammalian MAPK-IEG networkExamination of effects of GSK3beta phosphorylation, beta-catenin phosphorylation, and beta-catenin degradation on kinetics of Wnt signaling pathway using computational method.Liver stem cells and hepatocellular carcinoma.COMMD7 is correlated with a novel NF-κB positive feedback loop in hepatocellular carcinoma.Fibronectin extra domain A (EDA) sustains CD133(+)/CD44(+) subpopulation of colorectal cancer cells.Cancer stem cells and hepatocellular carcinomaNetwork quantification of EGFR signaling unveils potential for targeted combination therapy.A novel positive feedback loop involving FASN/p-ERK1/2/5-LOX/LTB4/FASN sustains high growth of breast cancer cells.Roles of the Ras/Raf/MEK/ERK pathway in leukemia therapy.
P2860
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P2860
A hidden oncogenic positive feedback loop caused by crosstalk between Wnt and ERK pathways.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
A hidden oncogenic positive fe ...... between Wnt and ERK pathways.
@en
type
label
A hidden oncogenic positive fe ...... between Wnt and ERK pathways.
@en
prefLabel
A hidden oncogenic positive fe ...... between Wnt and ERK pathways.
@en
P356
P1433
P1476
A hidden oncogenic positive fe ...... k between Wnt and ERK pathways
@en
P2888
P304
P356
10.1038/SJ.ONC.1210230
P407
P577
2007-01-22T00:00:00Z
P5875
P6179
1003830733