An injected bacterial effector targets chromatin access for transcription factor NF-kappaB to alter transcription of host genes involved in immune responses. - Wikidata - wikimedia - TriplyDB

An injected bacterial effector targets chromatin access for transcription factor NF-kappaB to alter transcription of host genes involved in immune responses.

An injected bacterial effector targets chromatin access for transcription factor NF-kappaB to alter transcription of host genes involved in immune responses.

http://www.wikidata.org/entity/Q40198172

about

A bacterial E3 ubiquitin ligase IpaH9.8 targets NEMO/IKKgamma to dampen the host NF-kappaB-mediated inflammatory response Bacterial effector binding to ribosomal protein s3 subverts NF-kappaB function Shigella flexneri type III secretion system effectors OspB and OspF target the nucleus to downregulate the host inflammatory response via interactions with retinoblastoma protein GEF-H1 mediated control of NOD1 dependent NF-kappaB activation by Shigella effectors Histone modifications induced by a family of bacterial toxins Implications of Spatiotemporal Regulation of Shigella flexneri Type Three Secretion Activity on Effector Functions: Think Globally, Act Locally Shigella IpaH Family Effectors as a Versatile Model for Studying Pathogenic Bacteria Subverting Toll-Like Receptor Signaling by Bacterial Pathogens Tyrosine phosphorylation and bacterial virulence Epigenetics and bacterial infections Bacterial Internalization, Localization, and Effectors Shape the Epithelial Immune Response during Shigella flexneri Infection Structural basis for the catalytic mechanism of phosphothreonine lyase Shigella: a model of virulence regulation in vivo.Intra-ChIP: studying gene regulation in an intracellular pathogen The effects of anthrax lethal toxin on host barrier function Anthrax lethal toxin disrupts intestinal barrier function and causes systemic infections with enteric bacteria IKKα contributes to canonical NF-κB activation downstream of Nod1-mediated peptidoglycan recognition Phenylbutyrate counteracts Shigella mediated downregulation of cathelicidin in rabbit lung and intestinal epithelia: a potential therapeutic strategy The M. tuberculosis HAD phosphatase (Rv3042c) interacts with host proteins and is inhibited by Clofazimine Helicobacter pylori-induced histone modification, associated gene expression in gastric epithelial cells, and its implication in pathogenesis.An image classification approach to analyze the suppression of plant immunity by the human pathogen Salmonella Typhimurium.Yeast functional genomic screens lead to identification of a role for a bacterial effector in innate immunity regulation Nod-like receptors: cytosolic watchdogs for immunity against pathogens.Distinct TLR- and NLR-mediated transcriptional responses to an intracellular pathogen.A functional genomic yeast screen to identify pathogenic bacterial proteins SpvC is a Salmonella effector with phosphothreonine lyase activity on host mitogen-activated protein kinases Characterisation of early mucosal and neuronal lesions following Shigella flexneri infection in human colon Gene Ontology annotation highlights shared and divergent pathogenic strategies of type III effector proteins deployed by the plant pathogen Pseudomonas syringae pv tomato DC3000 and animal pathogenic Escherichia coli strains Anthrax lethal toxin impairs IL-8 expression in epithelial cells through inhibition of histone H3 modification.Epigenetic silencing of host cell defense genes enhances intracellular survival of the rickettsial pathogen Anaplasma phagocytophilum.Toxoplasma gondii inhibits covalent modification of histone H3 at the IL-10 promoter in infected macrophages Anthrax SET protein: a potential virulence determinant that epigenetically represses NF-κB activation in infected macrophages.The type III effectors NleE and NleB from enteropathogenic E. coli and OspZ from Shigella block nuclear translocation of NF-kappaB p65.Bordetella evades the host immune system by inducing IL-10 through a type III effector, BopN Treponema denticola suppresses expression of human {beta}-defensin-3 in gingival epithelial cells through inhibition of the toll-like receptor 2 axis Histone methylation by NUE, a novel nuclear effector of the intracellular pathogen Chlamydia trachomatis Hijacking of the pleiotropic cytokine interferon-γ by the type III secretion system of Yersinia pestis NleC, a type III secretion protease, compromises NF-κB activation by targeting p65/RelA Effector bottleneck: microbial reprogramming of parasitized host cell transcription by epigenetic remodeling of chromatin structure.Genetic reprogramming of host cells by bacterial pathogens

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P2860

An injected bacterial effector targets chromatin access for transcription factor NF-kappaB to alter transcription of host genes involved in immune responses.

http://www.wikidata.org/entity/Q40198172

description

2006 nî lūn-bûn

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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2006年论文

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2006年论文

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name

An injected bacterial effector ...... involved in immune responses.

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An injected bacterial effector ...... involved in immune responses.

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An injected bacterial effector ...... involved in immune responses.

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Nature Immunology

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An injected bacterial effector ...... involved in immune responses.

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P2093

Bogdan Mateescu

http://www.w3.org/2001/XMLSchema#string

Christian Muchardt

http://www.w3.org/2001/XMLSchema#string

Claude Parsot

http://www.w3.org/2001/XMLSchema#string

Dong Wook Kim

http://www.w3.org/2001/XMLSchema#string

Eric Batsche

http://www.w3.org/2001/XMLSchema#string

Laurence Arbibe

http://www.w3.org/2001/XMLSchema#string

Philippe J Sansonetti

http://www.w3.org/2001/XMLSchema#string

Thierry Pedron

http://www.w3.org/2001/XMLSchema#string

P2860

The nucleosomal response associated with immediate-early gene induction is mediated via alternative MAP kinase cascades: MSK1 as a potential histone H3/HMG-14 kinase

The language of covalent histone modifications

Stress-induced map kinase Hog1 is part of transcription activation complexes.

Nod1 detects a unique muropeptide from gram-negative bacterial peptidoglycan

Phosphoacetylation of histone H3 on c-fos- and c-jun-associated nucleosomes upon gene activation

Novel sites in the p65 subunit of NF-kappaB interact with TFIIB to facilitate NF-kappaB induced transcription.

The Shigella flexneri effector OspG interferes with innate immune responses by targeting ubiquitin-conjugating enzymes

Protein tyrosine phosphatases: structure and function, substrate specificity, and inhibitor development.

Polymorphonuclear leukocyte transmigration promotes invasion of colonic epithelial monolayer by Shigella flexneri

A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion.

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10.1038/NI1423

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1

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8

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17159983

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