The putative zinc finger of the human cytomegalovirus IE2 86-kilodalton protein is dispensable for DNA binding and autorepression, thereby demarcating a concise core domain in the C terminus of the protein.
about
Autorepression of the human cytomegalovirus major immediate-early promoter/enhancer at late times of infection is mediated by the recruitment of chromatin remodeling enzymes by IE86Functional properties of the human cytomegalovirus IE86 protein required for transcriptional regulation and virus replicationEvidence that the human cytomegalovirus IE2-86 protein binds mdm2 and facilitates mdm2 degradationThe autoregulatory and transactivating functions of the human cytomegalovirus IE86 protein use independent mechanisms for promoter binding.Transactivation, dimerization, and DNA-binding activity of white spot syndrome virus immediate-early protein IE1Human cytomegalovirus IE1-72 protein interacts with p53 and inhibits p53-dependent transactivation by a mechanism different from that of IE2-86 proteinHuman Cytomegalovirus IE2 Protein Disturbs Brain Development by the Dysregulation of Neural Stem Cell Maintenance and the Polarization of Migrating Neurons.Design, synthesis, and evaluation of WC5 analogues as inhibitors of human cytomegalovirus Immediate-Early 2 protein, a promising target for anti-HCMV treatment.The 6-aminoquinolone WC5 inhibits human cytomegalovirus replication at an early stage by interfering with the transactivating activity of viral immediate-early 2 protein.
P2860
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P2860
The putative zinc finger of the human cytomegalovirus IE2 86-kilodalton protein is dispensable for DNA binding and autorepression, thereby demarcating a concise core domain in the C terminus of the protein.
description
2004 nî lūn-bûn
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2004年の論文
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2004年論文
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2004年論文
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2004年論文
@zh-hk
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name
The putative zinc finger of th ...... the C terminus of the protein.
@en
type
label
The putative zinc finger of th ...... the C terminus of the protein.
@en
prefLabel
The putative zinc finger of th ...... the C terminus of the protein.
@en
P2093
P2860
P1433
P1476
The putative zinc finger of th ...... the C terminus of the protein.
@en
P2093
Christian Hagemeier
Jasmin Asmar
Lüder Wiebusch
Matthias Truss
P2860
P304
11853-11864
P356
10.1128/JVI.78.21.11853-11864.2004
P407
P577
2004-11-01T00:00:00Z