Autocrine and juxtacrine effects of amphiregulin on the proliferative, invasive, and migratory properties of normal and neoplastic human mammary epithelial cells.
about
A phase II trial to assess efficacy and safety of afatinib in extensively pretreated patients with HER2-negative metastatic breast cancerEGFR ligands exhibit functional differences in models of paracrine and autocrine signalingAt the crossroads: EGFR and PTHrP signaling in cancer-mediated diseases of boneEGFR Tyrosine 845 Phosphorylation-Dependent Proliferation and Transformation of Breast Cancer Cells Require Activation of p38 MAPK.Epidermal growth factor-induced enhancement of glioblastoma cell migration in 3D arises from an intrinsic increase in speed but an extrinsic matrix- and proteolysis-dependent increase in persistence.Targeting GLI1 expression in human inflammatory breast cancer cells enhances apoptosis and attenuates migration.BRCA1 represses amphiregulin gene expression.YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway.GPER mediates estrogen-induced signaling and proliferation in human breast epithelial cells and normal and malignant breastThe effects of amphiregulin induced MMP-13 production in human osteoarthritis synovial fibroblast.An extensive survey of tyrosine phosphorylation revealing new sites in human mammary epithelial cellsDecreased autocrine EGFR signaling in metastatic breast cancer cells inhibits tumor growth in bone and mammary fat padInflammatory breast cancer (IBC): clues for targeted therapiesThe bacterial protein azurin impairs invasion and FAK/Src signaling in P-cadherin-overexpressing breast cancer cell models.Localization and function of a eukaryotic-initiation-factor-2-associated 67-kDa glycoprotein.The human adenocarcinoma-associated gene, AGR2, induces expression of amphiregulin through Hippo pathway co-activator YAP1 activationReactivation of estrogen receptor α by vorinostat sensitizes mesenchymal-like triple-negative breast cancer to aminoflavone, a ligand of the aryl hydrocarbon receptor.Oncogenic signaling in amphiregulin and EGFR-expressing PTEN-null human breast cancerSmall molecule inhibitors of the host cell COX/AREG/EGFR/ERK pathway attenuate cytomegalovirus-induced pathogenesisDeletion of p53 in human mammary epithelial cells causes chromosomal instability and altered therapeutic responseADAM-mediated amphiregulin shedding and EGFR transactivation.Platinum resistance in breast and ovarian cancer cell linesAutocrine production of amphiregulin predicts sensitivity to both gefitinib and cetuximab in EGFR wild-type cancers.Identification of targets for rational pharmacological therapy in childhood craniopharyngioma.MiR-34a suppresses amphiregulin and tumor metastatic potential of head and neck squamous cell carcinoma (HNSCC)Amphiregulin enhances alpha6beta1 integrin expression and cell motility in human chondrosarcoma cells through Ras/Raf/MEK/ERK/AP-1 pathway.Activating PIK3CA Mutations Induce an Epidermal Growth Factor Receptor (EGFR)/Extracellular Signal-regulated Kinase (ERK) Paracrine Signaling Axis in Basal-like Breast Cancer.Amphiregulin Is a Critical Downstream Effector of Estrogen Signaling in ERα-Positive Breast Cancer.EGF and amphiregulin differentially regulate Cbl recruitment to endosomes and EGF receptor fate.Amphiregulin enhances intercellular adhesion molecule-1 expression and promotes tumor metastasis in human osteosarcomaExosome-bound WD repeat protein Monad inhibits breast cancer cell invasion by degrading amphiregulin mRNABone Marrow CD11c+ Cell-Derived Amphiregulin Promotes Pulmonary FibrosisAltered EGFR localization and degradation in human breast cancer cells with an amphiregulin/EGFR autocrine loop.Y-box binding protein-1 serine 102 is a downstream target of p90 ribosomal S6 kinase in basal-like breast cancer cellsFunctional selectivity of EGF family peptide growth factors: implications for cancer.The proteome signature of the inflammatory breast cancer plasma membrane identifies novel molecular markers of diseaseADAM17 substrate release in proximal tubule drives kidney fibrosisAmphiregulin-EGFR signaling regulates PTHrP gene expression in breast cancer cells.The role of amphiregulin in exemestane-resistant breast cancer cells: evidence of an autocrine loop.Epidermal growth factor receptor pathway analysis identifies amphiregulin as a key factor for cisplatin resistance of human breast cancer cells.
P2860
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P2860
Autocrine and juxtacrine effects of amphiregulin on the proliferative, invasive, and migratory properties of normal and neoplastic human mammary epithelial cells.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Autocrine and juxtacrine effec ...... uman mammary epithelial cells.
@en
type
label
Autocrine and juxtacrine effec ...... uman mammary epithelial cells.
@en
prefLabel
Autocrine and juxtacrine effec ...... uman mammary epithelial cells.
@en
P2860
P356
P1476
Autocrine and juxtacrine effec ...... uman mammary epithelial cells.
@en
P2093
Nicole E Willmarth
Stephen P Ethier
P2860
P304
37728-37737
P356
10.1074/JBC.M606532200
P407
P577
2006-10-10T00:00:00Z