Modulation of function of three ABC drug transporters, P-glycoprotein (ABCB1), mitoxantrone resistance protein (ABCG2) and multidrug resistance protein 1 (ABCC1) by tetrahydrocurcumin, a major metabolite of curcumin.
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The Role of Natural Polyphenols in the Prevention and Treatment of Cervical Cancer-An OverviewPhytochemicals as Innovative Therapeutic Tools against Cancer Stem CellsSide population cells as prototype of chemoresistant, tumor-initiating cellsCurcumin as a Modulator of P-Glycoprotein in Cancer: Challenges and PerspectivesMolecular Mimics of Classic P-Glycoprotein Inhibitors as Multidrug Resistance Suppressors and Their Synergistic Effect on PaclitaxelChemoresistance in prostate cancer cells is regulated by miRNAs and Hedgehog pathwayFolate decorated dual drug loaded nanoparticle: role of curcumin in enhancing therapeutic potential of nutlin-3a by reversing multidrug resistanceSpecific increase in MDR1 mediated drug-efflux in human brain endothelial cells following co-exposure to HIV-1 and saquinavirIdentification of inhibitors of ABCG2 by a bioluminescence imaging-based high-throughput assay.Curcumin inhibits the side population (SP) phenotype of the rat C6 glioma cell line: towards targeting of cancer stem cells with phytochemicals.Distinct combinatorial effects of the plant polyphenols curcumin, carnosic acid, and silibinin on proliferation and apoptosis in acute myeloid leukemia cells.Transport in technicolor: mapping ATP-binding cassette transporters in sea urchin embryos.Targeting breast stem cells with the cancer preventive compounds curcumin and piperine.Potential application of curcumin and its analogues in the treatment strategy of patients with primary epithelial ovarian cancer.Effect of Supplementation of Tanshinone IIA and Sodium Tanshinone IIA Sulfonate on the Anticancer Effect of Epirubicin: An In Vitro Study.Synthesis and characterization of a BODIPY conjugate of the BCR-ABL kinase inhibitor Tasigna (nilotinib): evidence for transport of Tasigna and its fluorescent derivative by ABC drug transporters.Potential applications of curcumin and its novel synthetic analogs and nanotechnology-based formulations in cancer prevention and therapy.Discovering natural product modulators to overcome multidrug resistance in cancer chemotherapy.Targeting tumor ubiquitin-proteasome pathway with polyphenols for chemosensitization.Kuguacin J isolated from Momordica charantia leaves inhibits P-glycoprotein (ABCB1)-mediated multidrug resistance.MRP (ABCC) transporters-mediated efflux of anti-HIV drugs, saquinavir and zidovudine, from human endothelial cells.In vitro and in vivo modulation of ABCG2 by functionalized aurones and structurally related analogs.Curcumin inhibits the activity of ABCG2/BCRP1, a multidrug resistance-linked ABC drug transporter in mice.Curcumin circumvents chemoresistance in vitro and potentiates the effect of thalidomide and bortezomib against human multiple myeloma in nude mice modelCurcumin modulates efflux mediated by yeast ABC multidrug transporters and is synergistic with antifungals.Dietary regulation of P-gp function and expression.Solid lipid nanoparticles with TPGS and Brij 78: A co-delivery vehicle of curcumin and piperine for reversing P-glycoprotein-mediated multidrug resistance in vitro.Complex Interplay between the P-Glycoprotein Multidrug Efflux Pump and the Membrane: Its Role in Modulating Protein Function.Effects of curcumin on ion channels and transporters.Interactions of dietary phytochemicals with ABC transporters: possible implications for drug disposition and multidrug resistance in cancer.Novel anti-cancer compounds for developing combinatorial therapies to target anoikis-resistant tumors.Human ABCG2: structure, function, and its role in multidrug resistance.Secondary Metabolites from Plants Inhibiting ABC Transporters and Reversing Resistance of Cancer Cells and Microbes to Cytotoxic and Antimicrobial Agents.Nanoscale particulate systems for multidrug delivery: towards improved combination chemotherapy.Curcuma Contra Cancer? Curcumin and Hodgkin's Lymphoma.Curcumin differs from tetrahydrocurcumin for molecular targets, signaling pathways and cellular responses.Natural product modulators to overcome multidrug resistance in cancer.Tackling multidrug resistance mediated by efflux transporters in tumor-initiating cells.Reversal of human multi-drug resistance leukaemic cells by stemofoline derivatives via inhibition of P-glycoprotein function.FTY720 enhances chemosensitivity of colon cancer cells to doxorubicin and etoposide via the modulation of P-glycoprotein and multidrug resistance protein 1.
P2860
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P2860
Modulation of function of three ABC drug transporters, P-glycoprotein (ABCB1), mitoxantrone resistance protein (ABCG2) and multidrug resistance protein 1 (ABCC1) by tetrahydrocurcumin, a major metabolite of curcumin.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Modulation of function of thre ...... major metabolite of curcumin.
@en
type
label
Modulation of function of thre ...... major metabolite of curcumin.
@en
prefLabel
Modulation of function of thre ...... major metabolite of curcumin.
@en
P2093
P2860
P1476
Modulation of function of thre ...... a major metabolite of curcumin
@en
P2093
Chada Phisalphong
Suneet Shukla
Suresh V Ambudkar
Wanida Chearwae
P2860
P2888
P356
10.1007/S11010-006-9302-8
P577
2006-09-08T00:00:00Z