Pharmacokinetic investigation of sildenafil using positron emission tomography and determination of its effect on cerebrospinal fluid cGMP levels. - Wikidata - wikimedia - TriplyDB

Pharmacokinetic investigation of sildenafil using positron emission tomography and determination of its effect on cerebrospinal fluid cGMP levels.

Pharmacokinetic investigation of sildenafil using positron emission tomography and determination of its effect on cerebrospinal fluid cGMP levels.

http://www.wikidata.org/entity/Q40238471

about

Novel Radioligands for Cyclic Nucleotide Phosphodiesterase Imaging with Positron Emission Tomography: An Update on Developments Since 2012 Development of a New Radiofluorinated Quinoline Analog for PET Imaging of Phosphodiesterase 5 (PDE5) in Brain.Icariside II, a novel phosphodiesterase 5 inhibitor, protects against H2 O2 -induced PC12 cells death by inhibiting mitochondria-mediated autophagy The mechanism of attenuation of epithelial-mesenchymal transition by a phosphodiesterase 5 inhibitor via renal klotho expression.A First-in-Class Small-Molecule that Acts as a Dual Inhibitor of HDAC and PDE5 and that Rescues Hippocampal Synaptic Impairment in Alzheimer's Disease Mice.Effects of Sildenafil on Cerebrovascular Reactivity in Patients with Becker Muscular Dystrophy.Effects of sildenafil and calcitonin gene-related peptide on brainstem glutamate levels: a pharmacological proton magnetic resonance spectroscopy study at 3.0 T.

P2860

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P2860

Pharmacokinetic investigation of sildenafil using positron emission tomography and determination of its effect on cerebrospinal fluid cGMP levels.

http://www.wikidata.org/entity/Q40238471

description

2015 nî lūn-bûn

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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2015年论文

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2015年论文

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name

Pharmacokinetic investigation ...... rebrospinal fluid cGMP levels.

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Pharmacokinetic investigation ...... rebrospinal fluid cGMP levels.

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Pharmacokinetic investigation ...... rebrospinal fluid cGMP levels.

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P1433

Journal of Neurochemistry

P1476

Pharmacokinetic investigation ...... rebrospinal fluid cGMP levels.

@en

P2093

Ana Ugarte

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Carolina García-Barroso

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Iria G Dopeso-Reyes

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P2860

In vivo, in vitro and in silico methods for small molecule transfer across the BBB.

Sildenafil as a selective pulmonary vasodilator in childhood primary pulmonary hypertension.

Sildenafil restores cognitive function without affecting β-amyloid burden in a mouse model of Alzheimer's disease.

Magnetic resonance imaging investigation of axonal remodeling and angiogenesis after embolic stroke in sildenafil-treated rats

Phosphodiesterases in the central nervous system.

Subtype selectivity in phosphodiesterase 4 (PDE4): a bottleneck in rational drug design.

Longitudinal magnetic resonance imaging of sildenafil treatment of embolic stroke in aged rats.

Modulation of the ASK1-MKK3/6-p38/MAPK signalling pathway mediates sildenafil protection against chemical hypoxia caused by malonate.

Sildenafil protects against 3-nitropropionic acid neurotoxicity through the modulation of calpain, CREB, and BDNF.

Tadalafil crosses the blood-brain barrier and reverses cognitive dysfunction in a mouse model of AD.

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403-415

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10.1111/JNC.13454

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2

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136

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José L. Lanciego

Boguslaw Szczupak

Ana García-Osta

Mar Cuadrado-Tejedor

Julen Oyarzabal

Vanessa Gomez Vallejo

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2015-12-07T00:00:00Z

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26641206

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cerebrospinal fluid