The 37-kDa/67-kDa laminin receptor acts as a receptor for infectious prions and is inhibited by polysulfated glycanes.
about
Prion diseases: immunotargets and therapyCellular aspects of prion replication in vitroGetting a grip on prions: oligomers, amyloids, and pathological membrane interactions.Characterization of intracellular dynamics of inoculated PrP-res and newly generated PrP(Sc) during early stage prion infection in Neuro2a cells.From high-throughput cell culture screening to mouse model: identification of new inhibitor classes against prion disease.Inoculation of scrapie with the self-assembling RADA-peptide disrupts prion accumulation and extends hamster survival.The first report of RPSA polymorphisms, also called 37/67 kDa LRP/LR gene, in sporadic Creutzfeldt-Jakob disease (CJD).Axonal and transynaptic spread of prions.Green tea polyphenol EGCG sensing motif on the 67-kDa laminin receptorAlimentary prion infections: Touchdown in the intestine.Downregulation of the non-integrin laminin receptor reduces cellular viability by inducing apoptosis in lung and cervical cancer cellsOverexpression of PrPc, combined with MGr1-Ag/37LRP, is predictive of poor prognosis in gastric cancer.Adhesion and Invasion of Breast and Oesophageal Cancer Cells Are Impeded by Anti-LRP/LR-Specific Antibody IgG1-iS18.High resolution imaging study of interactions between the 37 kDa/67 kDa laminin receptor and APP, beta-secretase and gamma-secretase in Alzheimer's disease.Structural and mechanistic commonalities of amyloid-β and the prion proteinHeparan sulfate binding can contribute to the neurovirulence of neuroadapted and nonneuroadapted Sindbis viruses.Knockdown of LRP/LR Induces Apoptosis in Breast and Oesophageal Cancer CellsKnock-Down of the 37kDa/67kDa Laminin Receptor LRP/LR Impedes Telomerase ActivityRecent advances in prion chemotherapeutics.The cellular prion protein (PrP(C)): its physiological function and role in diseaseModulation of Glycosaminoglycans Affects PrPSc Metabolism but Does Not Block PrPSc Uptake.PrPc does not mediate internalization of PrPSc but is required at an early stage for de novo prion infection of Rov cells.Comprehensive proteomic analysis of nonintegrin laminin receptor interacting proteinsRecent developments in mucosal vaccines against prion diseases.Therapeutic approaches for prion disorders.Anti-LRP/LR antibody W3 hampers peripheral PrPSc propagation in scrapie infected mice.Anti-LRP/LR specific antibodies and shRNAs impede amyloid beta shedding in Alzheimer's disease.Anti-LRP/LR specific antibody IgG1-iS18 and knock-down of LRP/LR by shRNAs rescue cells from Aβ42 induced cytotoxicityTherapies for human prion diseasesAntibody-based immunotherapeutic attempts in experimental animal models of prion diseases.Looking into laminin receptor: critical discussion regarding the non-integrin 37/67-kDa laminin receptor/RPSA protein.De novo mammalian prion synthesis.Patented biological approaches for the therapeutic modulation of the 37 kDa/67 kDa laminin receptor.Cellular mechanisms of protein aggregate propagationLife cycle of cytosolic prions.Single-chain fragment variable passive immunotherapies for neurodegenerative diseases.Gene expression in the medulla following oral infection of cattle with bovine spongiform encephalopathy.Prion strains depend on different endocytic routes for productive infection.LRP/LR Antibody Mediated Rescuing of Amyloid-β-Induced Cytotoxicity is Dependent on PrPc in Alzheimer's Disease.The laminin receptor is a cellular attachment receptor for classical Swine Fever virus
P2860
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P2860
The 37-kDa/67-kDa laminin receptor acts as a receptor for infectious prions and is inhibited by polysulfated glycanes.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
The 37-kDa/67-kDa laminin rece ...... ited by polysulfated glycanes.
@en
type
label
The 37-kDa/67-kDa laminin rece ...... ited by polysulfated glycanes.
@en
prefLabel
The 37-kDa/67-kDa laminin rece ...... ited by polysulfated glycanes.
@en
P2093
P356
P1476
The 37-kDa/67-kDa laminin rece ...... ited by polysulfated glycanes.
@en
P2093
Clemence Rey
Corinne Ida Lasmezas
Daphne Nikles
Denis Barritault
Dulce Papy-Garcia
Sabine Gauczynski
Stefan Weiss
Susanne Alban
Susanne El-Gogo
P304
P356
10.1086/505914
P407
P577
2006-08-01T00:00:00Z