Opposite fate of endocytosed CCR7 and its ligands: recycling versus degradation.
about
Endocytic trafficking of chemokine receptorsEffect of adhesion and chemokine presentation on T-lymphocyte haptokinesis.Combinatorial guidance by CCR7 ligands for T lymphocytes migration in co-existing chemokine fieldsFusion of CCL21 non-migratory active breast epithelial and breast cancer cells give rise to CCL21 migratory active tumor hybrid cell linesEngineering chemoattractant gradients using chemokine-releasing polysaccharide microspheres.Convolution of chemoattractant secretion rate, source density, and receptor desensitization direct diverse migration patterns in leukocytesA microfluidic device for measuring cell migration towards substrate-bound and soluble chemokine gradients.Chemokine (C-C motif) receptor 7 (CCR7) associates with the tumour immune microenvironment but not progression in invasive breast carcinomaEmerging concepts and approaches for chemokine-receptor drug discovery.PGE(2) transiently enhances DC expression of CCR7 but inhibits the ability of DCs to produce CCL19 and attract naive T cells.Green fluorescent protein fused to peptide agonists of two dissimilar G protein-coupled receptors: novel ligands of the bradykinin B2 (rhodopsin family) receptor and parathyroid hormone PTH1 (secretin family) receptor.Dendritic cell chemotaxis in 3D under defined chemokine gradients reveals differential response to ligands CCL21 and CCL19.Assignment of CCR7 gene to chicken chromosome 27 by radiation hybrid panel mapping.Loss of Gadkin Affects Dendritic Cell Migration In VitroCCR7/CCL19 controls expression of EDG-1 in T cells.Distinct CCR7 glycosylation pattern shapes receptor signaling and endocytosis to modulate chemotactic responses.Adenovirus-engineered human dendritic cells induce natural killer cell chemotaxis via CXCL8/IL-8 and CXCL10/IP-10.Role of C-C chemokine receptor type 7 and its ligands during neuroinflammationCC-chemokine receptor 7 and its ligand CCL19 promote mitral valve interstitial cell migration and repair.Modulation of pulmonary dendritic cell function during mycobacterial infection.Targeting chemokine receptors in disease--a case study of CCR4Ectopic lymphoid tissue alters the chemokine gradient, increases lymphocyte retention and exacerbates murine ileitisSelective engagement of G protein coupled receptor kinases (GRKs) encodes distinct functions of biased ligands.DC-LAMP+ dendritic cells are recruited to gastric lymphoid follicles in Helicobacter pylori-infected individualsOn the move: endocytic trafficking in cell migration.A Novel Computational Model Predicts Key Regulators of Chemokine Gradient Formation in Lymph Nodes and Site-Specific Roles for CCL19 and ACKR4.Biased agonism at chemokine receptors: obstacles or opportunities for drug discovery?Differential CCR7 Targeting in Dendritic Cells by Three Naturally Occurring CC-Chemokines.C-C chemokine receptor-7 mediated endocytosis of antibody cargoes into intact cellsRole of the atypical chemoattractant receptor CRAM in regulating CCL19 induced CCR7 responses in B-cell chronic lymphocytic leukemia.Constitutive endocytosis of the chemokine CX3CL1 prevents its degradation by cell surface metalloproteases.Effects of Clostridium difficile toxin A and B on human T lymphocyte migration.Downmodulation of CCR7 by HIV-1 Vpu results in impaired migration and chemotactic signaling within CD4⁺ T cells.Synergy-inducing chemokines enhance CCR2 ligand activities on monocytes.p66Shc deficiency enhances CXCR4 and CCR7 recycling in CLL B cells by facilitating their dephosphorylation-dependent release from β-arrestin at early endosomes.New insights in chemokine signaling.Identification of truncated chemokine receptor 7 in human colorectal cancer unable to localize to the cell surface and unreactive to external ligands.Altered expression and endocytic function of CD205 in human dendritic cells, and detection of a CD205-DCL-1 fusion protein upon dendritic cell maturation.
P2860
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P2860
Opposite fate of endocytosed CCR7 and its ligands: recycling versus degradation.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Opposite fate of endocytosed CCR7 and its ligands: recycling versus degradation.
@en
type
label
Opposite fate of endocytosed CCR7 and its ligands: recycling versus degradation.
@en
prefLabel
Opposite fate of endocytosed CCR7 and its ligands: recycling versus degradation.
@en
P1476
Opposite fate of endocytosed CCR7 and its ligands: recycling versus degradation
@en
P2093
Marcus Groettrup
P304
P356
10.4049/JIMMUNOL.177.4.2314
P407
P577
2006-08-01T00:00:00Z