Endoglin promotes endothelial cell proliferation and TGF-beta/ALK1 signal transduction. - Wikidata - wikimedia - TriplyDB

Endoglin promotes endothelial cell proliferation and TGF-beta/ALK1 signal transduction.

Endoglin promotes endothelial cell proliferation and TGF-beta/ALK1 signal transduction.

http://www.wikidata.org/entity/Q40251249

about

Endoglin mediates fibronectin/α5β1 integrin and TGF-β pathway crosstalk in endothelial cells Critical role of endoglin in tumor cell plasticity of Ewing sarcoma and melanoma Hereditary haemorrhagic telangiectasia: a clinical and scientific review Hereditary haemorrhagic telangiectasia: current views on genetics and mechanisms of disease Cutting the brakes on hematopoietic regeneration by blocking TGFβ to limit chemotherapy-induced myelosuppression Safety of targeting tumor endothelial cell antigens Endothelial Plasticity: Shifting Phenotypes through Force Feedback Role of endoglin in fibrosis and scleroderma The role of transforming growth factor β1 in the regulation of blood pressure Vascular anomalies: from genetics toward models for therapeutic trials Age and diet affect gene expression profile in canine skeletal muscle Mononuclear cells and vascular repair in HHT Enhanced responses to angiogenic cues underlie the pathogenesis of hereditary hemorrhagic telangiectasia 2 LRG1 promotes angiogenesis by modulating endothelial TGF-β signalling.Endoglin haploinsufficiency promotes fibroblast accumulation during wound healing through Akt activation Identification of endoglin in rat hepatic stellate cells: new insights into transforming growth factor beta receptor signaling ALK5- and TGFBR2-independent role of ALK1 in the pathogenesis of hereditary hemorrhagic telangiectasia type 2 Inactivation of Smad5 in endothelial cells and smooth muscle cells demonstrates that Smad5 is required for cardiac homeostasis VE-cadherin is a critical endothelial regulator of TGF-beta signalling Modulation of NFkappaB activity and E-cadherin by the type III transforming growth factor beta receptor regulates cell growth and motility Increased Wnt5a in squamous cell lung carcinoma inhibits endothelial cell motility Mutation study of Spanish patients with hereditary hemorrhagic telangiectasia Mechanistic exploration of phthalimide neovascular factor 1 using network analysis tools.Endoglin and Alk5 regulate epithelial-mesenchymal transformation during cardiac valve formation.The type III TGFβ receptor regulates filopodia formation via a Cdc42-mediated IRSp53-N-WASP interaction in epithelial cells.ALK1 signalling analysis identifies angiogenesis related genes and reveals disparity between TGF-beta and constitutively active receptor induced gene expression A road map toward defining the role of Smad signaling in hematopoietic stem cells.Gene identification and analysis of transcripts differentially regulated in fracture healing by EST sequencing in the domestic sheep.Endoglin and activin receptor-like-kinase 1 are co-expressed in the distal vessels of the lung: implications for two familial vascular dysplasias, HHT and PAH.TGF-beta is required for vascular barrier function, endothelial survival and homeostasis of the adult microvasculature.Characterization of the human Activin-A receptor type II-like kinase 1 (ACVRL1) promoter and its regulation by Sp1 Endoglin: a novel target for therapeutic intervention in acute leukemias revealed in xenograft mouse models ALK5 phosphorylation of the endoglin cytoplasmic domain regulates Smad1/5/8 signaling and endothelial cell migration Endoglin Mediates Vascular Maturation by Promoting Vascular Smooth Muscle Cell Migration and Spreading.Endoglin in liver fibrogenesis: Bridging basic science and clinical practice Endothelial follistatin-like-1 regulates the postnatal development of the pulmonary vasculature by modulating BMP/Smad signaling.Lipocalin-7 is a matricellular regulator of angiogenesis Key role of the endothelial TGF-β/ALK1/endoglin signaling pathway in humans and rodents pulmonary hypertension.Modulation of circulating protein biomarkers following TRC105 (anti-endoglin antibody) treatment in patients with advanced cancer.Investigation of endoglin wild-type and missense mutant protein heterodimerisation using fluorescence microscopy based IF, BiFC and FRET analyses.

P2860

Q24297899-5E3C72E3-EF4F-4F97-AEC3-42A2B7A62370 Q24300402-588D5813-3AFF-450E-BC57-EDE70D8FE69D Q24600839-7F41C12C-B00B-4082-95C4-837F75D2CB51 Q24645017-B905872F-F3A0-44F1-B9BC-54E1E157F10F Q26745695-5497D0EA-5C26-4C03-AB3D-0BE14C7CB0BE Q26748863-F49F0BC2-41EF-458A-BC17-F5A57F00D3E1 Q26767430-CCB91141-E08F-47E1-9919-EE9188B94207 Q26821836-AA5C6EDC-3801-4AB0-A1F8-8024AB5CDE09 Q26998564-0AF019EE-362B-41D6-9912-9B1F5D636924 Q27025402-A95F1AF0-E256-4B4D-B215-D6E9EF5993A9 Q27355444-7D53483D-A807-400B-A1CF-25385473416C Q28084374-AD3B3783-EBA4-4B99-838A-12AF42672820 Q28487916-EA7D034E-8230-44CC-A6D5-BEDFD83FFF79 Q28508560-72DEAD61-D690-459C-A0ED-4A509BDC82DE Q28511364-F6312956-861A-4E8E-A8B7-3C1461C494E6 Q28575076-126B617C-FB77-49B3-9250-0B3CB18F23B5 Q28588420-18D138A0-8FA6-4284-AD69-076A4792D279 Q28592593-40ADD112-F919-4EA9-8BAE-C976427B47E9 Q28594650-79497DB9-8F8E-42B1-B27D-DC7703317123 Q28594979-04B55D2A-B617-4587-8891-2E0375741313 Q28820722-DF3F5A61-789B-49D7-844A-0E6EC5FA110F Q30371147-5D269F95-9034-4BA9-A64E-C128C1A57C51 Q30431758-E5C43E4E-5DE5-42F5-A106-059E6C041ADC Q30480194-85BDA780-50DF-4703-963E-0B9FCF2AAF10 Q30582833-24484025-E0D5-4EEE-B8A6-0DD11E969BAE Q30811602-477C3F76-2D39-40D6-8DCC-01D8B3835189 Q33229597-8E5A6CC4-1A90-402F-9FBA-630DEC15D191 Q33248963-8079A5FD-5037-444F-9970-F21AE387F5EA Q33385083-0CA44F4E-F433-4271-9F32-6F277382618E Q33425874-1662BA70-9041-42C9-97A4-F11C8FA4D199 Q33619784-2F03DE4C-E5C5-4727-9C97-2AB747B3F965 Q33640207-99596988-AB31-4399-BC32-ED70A5E629F2 Q33705264-5BC5151C-A3FC-40F6-9C29-6FC7E734A095 Q33727308-774B2A2C-B578-4E6A-B2F6-055BD1474E02 Q33728841-325ABDA3-6F24-4ECB-A7EE-D64EF9DBD5BF Q33738647-C87C867F-2E54-46BB-AF0E-D67AE8D5DB48 Q33749832-EE8AFDC4-94DF-4830-962B-7715F2611479 Q33793407-E42B9B0E-090C-469C-B60D-869956FC49E1 Q33913556-795B70F7-14C9-4267-B565-7B8A88972E67 Q33981941-B0382651-2123-4387-9392-84A8DBF15D6C

P2860

Endoglin promotes endothelial cell proliferation and TGF-beta/ALK1 signal transduction.

http://www.wikidata.org/entity/Q40251249

description

2004 nî lūn-bûn

@nan

2004年の論文

@ja

2004年論文

@yue

2004年論文

@zh-hant

2004年論文

@zh-hk

2004年論文

@zh-mo

2004年論文

@zh-tw

2004年论文

@wuu

2004年论文

@zh

2004年论文

@zh-cn

name

Endoglin promotes endothelial cell proliferation and TGF-beta/ALK1 signal transduction.

@en

type

label

Endoglin promotes endothelial cell proliferation and TGF-beta/ALK1 signal transduction.

@en

prefLabel

Endoglin promotes endothelial cell proliferation and TGF-beta/ALK1 signal transduction.

@en

P1433

Q40251249-50593B06-3DC8-4AB8-9440-8E7D50A8ED5B

P1476

Q40251249-EF647BDC-20EE-4EC2-94FB-579D749A9F34

P2093

Q40251249-2D95F599-80C2-4044-BA3D-6E2C0874082A

Q40251249-596556FF-F25B-45B9-8781-352AEED3C511

Q40251249-864316AF-DA58-4282-BE1C-D75FBD13BAAE

Q40251249-EFF0B27A-B064-46FE-81A9-00359FAB03BB

P2860

Q40251249-056BB439-8FFF-42A0-84F3-C14C1C89503C

Q40251249-12EFDFB4-D638-42CA-9029-E534F9A8DE6B

Q40251249-1A749469-C493-4C5F-AA6B-49F67C0CFB3F

Q40251249-2576C155-5E56-4745-8A8A-677904E1B67D

Q40251249-2893C38F-CFC5-4EBB-B2F6-2231031CDFC8

Q40251249-33F986D2-201E-4DFE-80A2-DA810EC85B11

Q40251249-3419E367-977A-4EF1-84AB-15ADA8CB88FD

Q40251249-358D94D6-602F-4AB3-8122-94B4C530F467

Q40251249-3C753355-4816-4059-86B9-7298CE80AD78

Q40251249-3ECE3AEF-77CE-4C3B-A910-4515BDA04255

P304

Q40251249-0F5ADCEE-3512-45CD-80B5-497A1F2E6646

P31

Q40251249-D2F85386-319F-4B67-95FC-20F37972E2CB

P356

Q40251249-B2245F0A-3B14-4A3B-AA23-281A6DAAF195

P407

Q40251249-B56ECADC-D063-4215-8424-2640BD607F30

P433

Q40251249-08291E23-1F06-45AE-B83E-EDD220060D04

P478

Q40251249-2BDF150E-0596-409C-8028-715FC9F7D379

P50

Q40251249-2BDDAF1C-179A-4CAE-AB67-AC9974FF9FD6

Q40251249-BBD7DA64-A882-4FE5-AEED-FD49DE635A4F

Q40251249-CF4C2BA7-B4D2-417B-A806-B0749DF86206

Q40251249-E34520EB-2B22-416F-9BB6-8E10A4019C38

Q40251249-EDEE0821-0D45-4A82-AAD3-3C4F6AE1C6EF

P577

Q40251249-5C69E406-E0B9-4BE9-B789-A25D6E876DF9

P5875

Q40251249-8D127E96-94B2-4943-B3F7-608033D1E0A0

P698

Q40251249-2587D388-52D7-428E-906C-BFA6F64D2E2C

P921

Q40251249-8F86FE42-EFC3-42BD-B12F-7704791910AA

P932

Q40251249-0B24A443-A3AC-46CE-AB03-87790E5FF42A

P356

SJ.EMBOJ.7600386

P1433

The EMBO Journal

P1476

Endoglin promotes endothelial cell proliferation and TGF-beta/ALK1 signal transduction.

@en

P2093

Marie-José Goumans

http://www.w3.org/2001/XMLSchema#string

Midory Thorikay

http://www.w3.org/2001/XMLSchema#string

Peter ten Dijke

http://www.w3.org/2001/XMLSchema#string

Rita L C Carvalho

http://www.w3.org/2001/XMLSchema#string

P2860

Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-beta superfamily

Endoglin: An accessory component of the TGF-beta-binding receptor-complex with diagnostic, prognostic, and bioimmunotherapeutic potential in human malignancies

Extracellular and cytoplasmic domains of endoglin interact with the transforming growth factor-beta receptors I and II

Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling

Regulated expression on human macrophages of endoglin, an Arg-Gly-Asp-containing surface antigen

TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4

Molecular characterization and in situ localization of murine endoglin reveal that it is a transforming growth factor-beta binding protein of endothelial and stromal cells

Endoglin, a TGF-beta binding protein of endothelial cells, is the gene for hereditary haemorrhagic telangiectasia type 1

Endoglin is a component of the transforming growth factor-beta receptor system in human endothelial cells

Activin receptor-like kinase 1 modulates transforming growth factor-beta 1 signaling in the regulation of angiogenesis

P304

4018-4028

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/SJ.EMBOJ.7600386

http://www.w3.org/2001/XMLSchema#string

P407

P433

20

http://www.w3.org/2001/XMLSchema#string

P478

23

http://www.w3.org/2001/XMLSchema#string

P50

Christine Mummery

Helen M. Arthur

Gudrun Valdimarsdottir

P577

2004-09-23T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

8328961

http://www.w3.org/2001/XMLSchema#string

P698

15385967

http://www.w3.org/2001/XMLSchema#string

P921

P932

524335

http://www.w3.org/2001/XMLSchema#string