A model for the solution structure of the rod arrestin tetramer.
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Crystal Structure of Arrestin-3 Reveals the Basis of the Difference in Receptor Binding Between Two Non-visual SubtypesIterative Molecular Dynamics-Rosetta Protein Structure Refinement Protocol to Improve Model Quality.Probing Protein Secondary Structure using EPR: Investigating a Dynamic Region of Visual Arrestin.Improved cryoEM-Guided Iterative Molecular Dynamics--Rosetta Protein Structure Refinement Protocol for High Precision Protein Structure Prediction.EM-fold: De novo folding of alpha-helical proteins guided by intermediate-resolution electron microscopy density maps.Practically useful: what the Rosetta protein modeling suite can do for youComputational methods in drug discovery.EM-fold: de novo atomic-detail protein structure determination from medium-resolution density maps.Transport and localization of signaling proteins in ciliated cellsProgressive reduction of its expression in rods reveals two pools of arrestin-1 in the outer segment with different roles in photoresponse recovery.Arrestin-1 expression level in rods: balancing functional performance and photoreceptor health.Monomeric rhodopsin is sufficient for normal rhodopsin kinase (GRK1) phosphorylation and arrestin-1 bindingRobust self-association is a common feature of mammalian visual arrestin-1.Few residues within an extensive binding interface drive receptor interaction and determine the specificity of arrestin proteins.The functional cycle of visual arrestins in photoreceptor cells.Steric volume exclusion sets soluble protein concentrations in photoreceptor sensory cilia.Conformation of receptor-bound visual arrestin.Involvement of distinct arrestin-1 elements in binding to different functional forms of rhodopsinEngineering visual arrestin-1 with special functional characteristicsCritical role of the central 139-loop in stability and binding selectivity of arrestin-1.The AP-2 adaptor beta2 appendage scaffolds alternate cargo endocytosis.Constitutively active rhodopsin mutants causing night blindness are effectively phosphorylated by GRKs but differ in arrestin-1 bindingDetermination of interspin distance distributions by cw-ESR is a single linear inverse problem.The role of arrestin alpha-helix I in receptor binding.Functional map of arrestin-1 at single amino acid resolutionCustom-designed proteins as novel therapeutic tools? The case of arrestins.The cytoplasmic rhodopsin-protein interface: potential for drug discovery.Structural determinants of arrestin functionsBeyond traditional pharmacology: new tools and approaches.Uncovering missing pieces: duplication and deletion history of arrestins in deuterostomes.Nonvisual arrestins function as simple scaffolds assembling the MKK4-JNK3α2 signaling complexThe structure of p85ni in class IA phosphoinositide 3-kinase exhibits interdomain disorder.Computer modeling of nitroxide spin labels on proteins.Elucidation of inositol hexaphosphate and heparin interaction sites and conformational changes in arrestin-1 by solution nuclear magnetic resonance.Self-association of arrestin family members.Rapid degeneration of rod photoreceptors expressing self-association-deficient arrestin-1 mutant.Arrestins in apoptosis.Therapeutic potential of small molecules and engineered proteins.Ubiquitin ligase parkin promotes Mdm2-arrestin interaction but inhibits arrestin ubiquitinationEnhanced phosphorylation-independent arrestins and gene therapy.
P2860
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P2860
A model for the solution structure of the rod arrestin tetramer.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
A model for the solution structure of the rod arrestin tetramer.
@en
type
label
A model for the solution structure of the rod arrestin tetramer.
@en
prefLabel
A model for the solution structure of the rod arrestin tetramer.
@en
P2093
P2860
P50
P1433
P1476
A model for the solution structure of the rod arrestin tetramer.
@en
P2093
Candice S Klug
Derek J Francis
Eric S Dawson
Ned Van Eps
Susan M Hanson
P2860
P304
P356
10.1016/J.STR.2008.03.006
P577
2008-06-01T00:00:00Z