A role for the G12 family of heterotrimeric G proteins in prostate cancer invasion. - Wikidata - wikimedia - TriplyDB

A role for the G12 family of heterotrimeric G proteins in prostate cancer invasion.

A role for the G12 family of heterotrimeric G proteins in prostate cancer invasion.

http://www.wikidata.org/entity/Q40264901

about

Differential G protein subunit expression by prostate cancer cells and their interaction with CXCR5 RhoA as a mediator of clinically relevant androgen action in prostate cancer cells Ras superfamily GEFs and GAPs: validated and tractable targets for cancer therapy?Myocardin is differentially required for the development of smooth muscle cells and cardiomyocytes LARG and mDia1 link Galpha12/13 to cell polarity and microtubule dynamics.Tre1 GPCR initiates germ cell transepithelial migration by regulating Drosophila melanogaster E-cadherin Prostate cancer invasion and metastasis: insights from mining genomic data.Extra-nuclear signaling of progesterone receptor to breast cancer cell movement and invasion through the actin cytoskeleton.CCK activates RhoA and Rac1 differentially through Galpha13 and Galphaq in mouse pancreatic acini.Breast cancer cell invasion mediated by Gα12 signaling involves expression of interleukins-6 and -8, and matrix metalloproteinase-2.Heterotrimeric G protein signaling outside the realm of seven transmembrane domain receptors G12 signaling through c-Jun NH2-terminal kinase promotes breast cancer cell invasion.The thromboxane synthase and receptor signaling pathway in cancer: an emerging paradigm in cancer progression and metastasis.Activation of Rap1 promotes prostate cancer metastasis Novel somatic mutations in heterotrimeric G proteins in melanoma Heterotrimeric G-protein alpha-12 (Gα12) subunit promotes oral cancer metastasis.Gα₁₂ drives invasion of oral squamous cell carcinoma through up-regulation of proinflammatory cytokines Cholecystokinin-mediated RhoGDI phosphorylation via PKCα promotes both RhoA and Rac1 signaling.MicroRNA-31 controls G protein alpha-13 (GNA13) expression and cell invasion in breast cancer cells Cannabinoid receptor type 1 (CB1) activation inhibits small GTPase RhoA activity and regulates motility of prostate carcinoma cells.Gastrin-stimulated Gα13 Activation of Rgnef Protein (ArhGEF28) in DLD-1 Colon Carcinoma Cells.ROCK1 feedback regulation of the upstream small GTPase RhoA Alterations in an inositol phosphate code through synergistic activation of a G protein and inositol phosphate kinases Cancer Cell Invasion in Three-dimensional Collagen Is Regulated Differentially by Gα13 Protein and Discoidin Domain Receptor 1-Par3 Protein Signaling MicroRNA-182 and microRNA-200a control G-protein subunit α-13 (GNA13) expression and cell invasion synergistically in prostate cancer cells.Inactivating mutations in GNA13 and RHOA in Burkitt's lymphoma and diffuse large B-cell lymphoma: a tumor suppressor function for the Gα13/RhoA axis in B cells.G protein α12 (Gα12) is a negative regulator of kidney injury molecule-1-mediated efferocytosis.Upregulation of PIP3-dependent Rac exchanger 1 (P-Rex1) promotes prostate cancer metastasis.Arachidonic acid stimulates cell adhesion through a novel p38 MAPK-RhoA signaling pathway that involves heat shock protein 27.Pharmacological targeting of CXCL12/CXCR4 signaling in prostate cancer bone metastasis Regulation and physiological functions of G12/13-mediated signaling pathways.Role of G12 proteins in oncogenesis and metastasis Site-specific metastasis formation: chemokines as regulators of tumor cell adhesion, motility and invasion.Heterotrimeric G proteins and apoptosis: intersecting signaling pathways leading to context dependent phenotypes Roles of Eicosanoids in Prostate Cancer.Gα12 structural determinants of Hsp90 interaction are necessary for serum response element-mediated transcriptional activation.Gα12 gep oncogene deregulation of p53-responsive microRNAs promotes epithelial-mesenchymal transition of hepatocellular carcinoma.RGIFE: a ranked guided iterative feature elimination heuristic for the identification of biomarkers.c-Jun Contributes to Transcriptional Control of GNA12 Expression in Prostate Cancer Cells.Regulation of E3 ubiquitin ligase-1 (WWP1) by microRNA-452 inhibits cancer cell migration and invasion in prostate cancer.

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P2860

A role for the G12 family of heterotrimeric G proteins in prostate cancer invasion.

http://www.wikidata.org/entity/Q40264901

description

2006 nî lūn-bûn

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2006年の論文

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2006年论文

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2006年论文

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2006年论文

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name

A role for the G12 family of heterotrimeric G proteins in prostate cancer invasion.

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type

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A role for the G12 family of heterotrimeric G proteins in prostate cancer invasion.

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A role for the G12 family of heterotrimeric G proteins in prostate cancer invasion.

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A role for the G12 family of heterotrimeric G proteins in prostate cancer invasion.

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P2093

John F Madden

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Laura N Stemmle

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Patrick J Casey

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Patrick Kelly

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Timothy A Fields

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Yehia Daaka

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P2860

A novel PDZ domain containing guanine nucleotide exchange factor links heterotrimeric G proteins to Rho

Vascular system defects and impaired cell chemokinesis as a result of Galpha13 deficiency

Essential role for Galpha13 in endothelial cells during embryonic development

Interaction of Galpha 12 and Galpha 13 with the cytoplasmic domain of cadherin provides a mechanism for beta -catenin release

Expression cDNA cloning of a transforming gene encoding the wild-type G alpha 12 gene product

Epithelial-mesenchymal transitions in tumour progression

Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis

Leukemia-associated Rho guanine nucleotide exchange factor (LARG) links heterotrimeric G proteins of the G(12) family to Rho

Mapping the Galpha13 binding interface of the rgRGS domain of p115RhoGEF

PAR1-mediated NFkappaB activation promotes survival of prostate cancer cells through a Bcl-xL-dependent mechanism

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10.1074/JBC.M604376200

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36

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281

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