Comparative selectivity and specificity of the proteasome inhibitors BzLLLCOCHO, PS-341, and MG-132.
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Alterations of the intracellular peptidome in response to the proteasome inhibitor bortezomibHECT E3 ubiquitin ligase Nedd4-1 ubiquitinates ACK and regulates epidermal growth factor (EGF)-induced degradation of EGF receptor and ACKRegulation of the proteasome by ATP: implications for ischemic myocardial injury and donor heart preservationElucidation of the α-keto-aldehyde binding mechanism: a lead structure motif for proteasome inhibitionCDK Inhibitors Roscovitine and CR8 Trigger Mcl-1 Down-Regulation and Apoptotic Cell Death in Neuroblastoma CellsUBXD4, a UBX-containing protein, regulates the cell surface number and stability of alpha3-containing nicotinic acetylcholine receptorsProteasome inhibitors alter levels of intracellular peptides in HEK293T and SH-SY5Y cellsPhase 1 study of marizomib in relapsed or relapsed and refractory multiple myeloma: NPI-0052-101 Part 1Effects of a novel proteasome inhibitor BU-32 on multiple myeloma cells.The small heat shock protein B8 (HSPB8) confers resistance to bortezomib by promoting autophagic removal of misfolded proteins in multiple myeloma cells.Mutual antagonism of Wilms' tumor 1 and β-catenin dictates podocyte health and disease.Natural compounds with proteasome inhibitory activity for cancer prevention and treatment.Bortezomib as the first proteasome inhibitor anticancer drug: current status and future perspectives.Reduced Levels of Proteasome Products in a Mouse Striatal Cell Model of Huntington's Disease.Combination with bortezomib enhances the antitumor effects of nanoparticle-encapsulated thiostrepton.The proteasomal and apoptotic phenotype determine bortezomib sensitivity of non-small cell lung cancer cells.Combination of proteasome inhibitors bortezomib and NPI-0052 trigger in vivo synergistic cytotoxicity in multiple myelomaInhibition of proteasome activity by the dietary flavonoid apigenin is associated with growth inhibition in cultured breast cancer cells and xenograftsA novel proteasome inhibitor NPI-0052 as an anticancer therapy.New applications of old metal-binding drugs in the treatment of human cancer.Conserved Sequence Preferences Contribute to Substrate Recognition by the Proteasome.Activity-based imaging probes of the proteasome.Proteasomal regulation of caspase-8 in cancer cell apoptosisThe tumor proteasome as a novel target for gold(III) complexes: implications for breast cancer therapyBU-32: a novel proteasome inhibitor for breast cancer.DNA repair pathways in human multiple myeloma: role in oncogenesis and potential targets for treatment.Crude and purified proteasome activity assays are affected by type of microplate.Effects of an anticarcinogenic Bowman-Birk protease inhibitor on purified 20S proteasome and MCF-7 breast cancer cells.Synergistic effects of proteasome inhibitor carfilzomib in combination with tyrosine kinase inhibitors in imatinib-sensitive and -resistant chronic myeloid leukemia models.Exocytosis of polyubiquitinated proteins in bortezomib-resistant leukemia cells: a role for MARCKS in acquired resistance to proteasome inhibitors.Inhibitors for the immuno- and constitutive proteasome: current and future trends in drug development.Caspase control: protagonists of cancer cell apoptosis.Peptide-based proteasome inhibitors in anticancer drug design.The future of proteasome inhibitors in relapsed/refractory multiple myeloma.Cell Cycle-independent Role of Cyclin D3 in Host Restriction of Influenza Virus Infection.Bortezomib-resistance is associated with increased levels of proteasome subunits and apoptosis-avoidanceActivity-based probes for the multicatalytic proteasome.Baicalin and scutellarin are proteasome inhibitors that specifically target chymotrypsin-like catalytic activity.Impaired bortezomib binding to mutant β5 subunit of the proteasome is the underlying basis for bortezomib resistance in leukemia cells.Chemical proteomics discloses petrosapongiolide M, an antiinflammatory marine sesterterpene, as a proteasome inhibitor.
P2860
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P2860
Comparative selectivity and specificity of the proteasome inhibitors BzLLLCOCHO, PS-341, and MG-132.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Comparative selectivity and sp ...... zLLLCOCHO, PS-341, and MG-132.
@en
type
label
Comparative selectivity and sp ...... zLLLCOCHO, PS-341, and MG-132.
@en
prefLabel
Comparative selectivity and sp ...... zLLLCOCHO, PS-341, and MG-132.
@en
P2093
P1433
P1476
Comparative selectivity and sp ...... zLLLCOCHO, PS-341, and MG-132.
@en
P2093
Alexandra E Irvine
Brian Walker
Dharminder Chauhan
Lisa J A Crawford
Treen C M Morris
P304
P356
10.1158/0008-5472.CAN-06-0605
P407
P577
2006-06-01T00:00:00Z