TLR5-mediated phosphoinositide 3-kinase activation negatively regulates flagellin-induced proinflammatory gene expression.
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TLR5 and Ipaf: dual sensors of bacterial flagellin in the innate immune systemThe Toll-Like Receptor 5 Agonist Entolimod Mitigates Lethal Acute Radiation Syndrome in Non-Human PrimatesGenkwanin inhibits proinflammatory mediators mainly through the regulation of miR-101/MKP-1/MAPK pathway in LPS-activated macrophages.Toll-like receptor signaling in cell proliferation and survivalInsulin modulates the inflammatory granulocyte response to streptococci via phosphatidylinositol 3-kinase.Bifidobacterium breve MCC-117 Induces Tolerance in Porcine Intestinal Epithelial Cells: Study of the Mechanisms Involved in the Immunoregulatory Effect.Genetic analysis of the role of the PI3K-Akt pathway in lipopolysaccharide-induced cytokine and tissue factor gene expression in monocytes/macrophages.PAR1- and PAR2-induced innate immune markers are negatively regulated by PI3K/Akt signaling pathway in oral keratinocytes.Toll-like receptors in inflammatory bowel diseases: a decade later.The p110α and p110β isoforms of class I phosphatidylinositol 3-kinase are involved in toll-like receptor 5 signaling in epithelial cellsTLR2-dependent activation of β-catenin pathway in dendritic cells induces regulatory responses and attenuates autoimmune inflammation.An agonist of toll-like receptor 5 has radioprotective activity in mouse and primate models.Enhancement of host immune responses by oral vaccination to Salmonella enterica serovar Typhimurium harboring both FliC and FljB flagellaInvolvement of Toll-like receptor 5 in the recognition of flagellated bacteria.mTORC1 Regulates Flagellin-Induced Inflammatory Response in MacrophagesThe role of phosphoinositide 3-kinase signaling in intestinal inflammationInhibition of serum- and glucocorticoid-inducible kinase 1 enhances TLR-mediated inflammation and promotes endotoxin-driven organ failure.Mucosal adjuvant activity of flagellin in aged mice.TLR5, a novel and unidentified inflammatory mediator in rheumatoid arthritis that correlates with disease activity score and joint TNF-α levels.Mammalian target of rapamycin and glycogen synthase kinase 3 differentially regulate lipopolysaccharide-induced interleukin-12 production in dendritic cells.Chronic Akt activation attenuated lipopolysaccharide-induced cardiac dysfunction via Akt/GSK3β-dependent inhibition of apoptosis and ER stressLipopolysaccharide activates innate immune responses in murine intestinal myofibroblasts through multiple signaling pathways.TLR4/MyD88/PI3K interactions regulate TLR4 signaling.ATP-mediated activation of the NADPH oxidase DUOX1 mediates airway epithelial responses to bacterial stimuli.Outer membrane vesicles from flagellin-deficient Salmonella enterica serovar Typhimurium induce cross-reactive immunity and provide cross-protection against heterologous Salmonella challengeFunctional characterisation of bovine TLR5 indicates species-specific recognition of flagellin.Cellular and molecular biology of airway mucins.Regulation of toll-like receptors-mediated inflammation by immunobiotics in bovine intestinal epitheliocytes: role of signaling pathways and negative regulatorsThe differential effects of 1,25-dihydroxyvitamin D3 on Salmonella-induced interleukin-8 and human beta-defensin-2 in intestinal epithelial cells.Membrane-tethered MUC1 mucin is phosphorylated by epidermal growth factor receptor in airway epithelial cells and associates with TLR5 to inhibit recruitment of MyD88.MUC1 mucin is a negative regulator of toll-like receptor signaling.Phosphoinositide 3-kinase is activated by MUC1 but not responsible for MUC1-induced suppression of Toll-like receptor 5 signaling.TLR5 Activation through NF-κB Is a Neuroprotective Mechanism of Postconditioning after Cerebral Ischemia in Mice.Altered macrophage function contributes to colitis in mice defective in the phosphoinositide-3 kinase subunit p110δ.Tumor suppressor Foxo3a is involved in the regulation of lipopolysaccharide-induced interleukin-8 in intestinal HT-29 cellsDistinct signaling mechanisms activate the target of rapamycin in response to different B-cell stimuli.Host species adaptation of TLR5 signalling and flagellin recognition.Toll-like receptor 5 deficiency exacerbates cardiac injury and inflammation induced by myocardial ischaemia-reperfusion in the mouse.Identification of a novel negative role of flagellin in regulating IL-10 production.ZSTK474, a novel PI3K inhibitor, modulates human CD14+ monocyte-derived dendritic cell functions and suppresses experimental autoimmune encephalomyelitis.
P2860
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P2860
TLR5-mediated phosphoinositide 3-kinase activation negatively regulates flagellin-induced proinflammatory gene expression.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
TLR5-mediated phosphoinositide ...... oinflammatory gene expression.
@en
type
label
TLR5-mediated phosphoinositide ...... oinflammatory gene expression.
@en
prefLabel
TLR5-mediated phosphoinositide ...... oinflammatory gene expression.
@en
P2093
P1476
TLR5-mediated phosphoinositide ...... oinflammatory gene expression.
@en
P2093
Andrew S Neish
Andrew T Gewirtz
Shigenori Nagai
Shigeo Koyasu
P304
P356
10.4049/JIMMUNOL.176.10.6194
P407
P577
2006-05-01T00:00:00Z