Oxidative stress induces a prolonged but reversible arrest in p53-null cancer cells, involving a Chk1-dependent G2 checkpoint. - Wikidata - wikimedia - TriplyDB

Oxidative stress induces a prolonged but reversible arrest in p53-null cancer cells, involving a Chk1-dependent G2 checkpoint.

Oxidative stress induces a prolonged but reversible arrest in p53-null cancer cells, involving a Chk1-dependent G2 checkpoint.

http://www.wikidata.org/entity/Q40284724

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Cancer cell survival following DNA damage-mediated premature senescence is regulated by mammalian target of rapamycin (mTOR)-dependent Inhibition of sirtuin 1 Upregulation of Nox4 in the aging vasculature and its association with smooth muscle cell polyploidy The mismatch repair system modulates curcumin sensitivity through induction of DNA strand breaks and activation of G2-M checkpoint.CPEB regulation of human cellular senescence, energy metabolism, and p53 mRNA translation Turning off the G2 DNA damage checkpoint.Regulation of Chk1 by its C-terminal domain.Identification of potential therapeutic targets in malignant mesothelioma using cell-cycle gene expression analysis Cutting edge: Chk1 directs senescence and mitotic catastrophe in recovery from G₂ checkpoint arrest.Sp1 is involved in H2O2-induced PUMA gene expression and apoptosis in colorectal cancer cells.p53 regulates a non-apoptotic death induced by ROS.

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P2860

Oxidative stress induces a prolonged but reversible arrest in p53-null cancer cells, involving a Chk1-dependent G2 checkpoint.

http://www.wikidata.org/entity/Q40284724

description

2006 nî lūn-bûn

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2006年の論文

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Oxidative stress induces a pro ...... a Chk1-dependent G2 checkpoint

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A Kosoy

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M J O'Connell

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S A Aaronson

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S W Lee

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P2860

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts

Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints.

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence

p53, the cellular gatekeeper for growth and division

WAF1, a potential mediator of p53 tumor suppression

The DNA damage response: putting checkpoints in perspective

Oxidants, oxidative stress and the biology of ageing

Cell death by mitotic catastrophe: a molecular definition

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6037-6047

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