PRL tyrosine phosphatases regulate rho family GTPases to promote invasion and motility.
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Silencing of RhoA and RhoC expression by RNA interference suppresses human colorectal carcinoma growth in vivoPhosphatase of regenerating liver 2 (PRL2) is essential for placental development by down-regulating PTEN (Phosphatase and Tensin Homologue Deleted on Chromosome 10) and activating Akt proteinProtein-tyrosine phosphatase 4A3 (PTP4A3) promotes vascular endothelial growth factor signaling and enables endothelial cell motility.Drosophila PRL-1 is a growth inhibitor that counteracts the function of the Src oncogenePRL-1 Protein Promotes ERK1/2 and RhoA Protein Activation through a Non-canonical Interaction with the Src Homology 3 Domain of p115 Rho GTPase-activating ProteinPRL-3, a metastasis associated tyrosine phosphatase, is involved in FLT3-ITD signaling and implicated in anti-AML therapyA systematic comparison of copy number alterations in four types of female cancerRhoC Promotes Metastasis via Activation of the Pyk2 Pathway in Prostate CancerPhotooxygenation of an amino-thienopyridone yields a more potent PTP4A3 inhibitor.Metastasis-associated phosphatase PRL-2 regulates tumor cell migration and invasion.Targeted deletion of the metastasis-associated phosphatase Ptp4a3 (PRL-3) suppresses murine colon cancer.Opposing roles of p190RhoGAP and Ect2 RhoGEF in regulating cytokinesis.Investigational inhibitors of PTP4A3 phosphatase as antineoplastic agents.Integrated analysis of global mRNA and protein expression data in HEK293 cells overexpressing PRL-1.Phosphatase of regenerating liver-3 localizes to cyto-membrane and is required for B16F1 melanoma cell metastasis in vitro and in vivoTargeting PTPs with small molecule inhibitors in cancer treatmentEndosialin expression in relation to clinicopathological and biological variables in rectal cancers with a Swedish clinical trial of preoperative radiotherapy.PRL-3 and E-cadherin show mutual interactions and participate in lymph node metastasis formation in gastric cancerThe Eyes Absent phosphatase-transactivator proteins promote proliferation, transformation, migration, and invasion of tumor cellsTherapeutic intervention based on protein prenylation and associated modificationsOncogenic function and prognostic significance of protein tyrosine phosphatase PRL-1 in hepatocellular carcinomaPhosphatase of regenerating liver-1 promotes cell migration and invasion and regulates filamentous actin dynamics.A PTP4A3 peptide PIMAP39 modulates TNF-alpha levels and endotoxic shock.A role of autophagy in PTP4A3-driven cancer progression.Phosphatase of regenerating liver: a novel target for cancer therapy.Src-mediated phosphorylation of the tyrosine phosphatase PRL-3 is required for PRL-3 promotion of Rho activation, motility and invasionTargeting protein tyrosine phosphatases for anticancer drug discovery.Protein tyrosine phosphatase of liver regeneration-1 is required for normal timing of cell cycle progression during liver regeneration.Correlation between Liver Metastases and the Level of PRL-3 mRNA Expression in Patients with Primary Colorectal Cancer.PRL-3 siRNA inhibits the metastasis of B16-BL6 mouse melanoma cells in vitro and in vivo.Mechanisms regulating colorectal cancer cell metastasis into liver (Review).miR-21, miR-17 and miR-19a induced by phosphatase of regenerating liver-3 promote the proliferation and metastasis of colon cancer.Overexpression and involvement in migration by the metastasis-associated phosphatase PRL-3 in human myeloma cellsStARD13(Dlc-2) RhoGap mediates ceramide activation of phosphatidylglycerolphosphate synthase and drug response in Chinese hamster ovary cells.Is there a genetic signature for liver metastasis in colorectal cancer?Protein tyrosine phosphatases: dual-specificity phosphatases in health and disease.Expression of phosphatase regenerating liver 3 is an independent prognostic indicator for gastric cancerPRL-3 promotes cell adhesion by interacting with JAM2 in colon cancer.Phosphatase of regenerating liver-3 inhibits invasiveness and proliferation in non-small cell lung cancer by regulating the epithelial-mesenchymal transition.Oncogenic roles of PRL-3 in FLT3-ITD induced acute myeloid leukaemia.
P2860
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P2860
PRL tyrosine phosphatases regulate rho family GTPases to promote invasion and motility.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
PRL tyrosine phosphatases regulate rho family GTPases to promote invasion and motility.
@en
type
label
PRL tyrosine phosphatases regulate rho family GTPases to promote invasion and motility.
@en
prefLabel
PRL tyrosine phosphatases regulate rho family GTPases to promote invasion and motility.
@en
P2093
P1433
P1476
PRL tyrosine phosphatases regulate rho family GTPases to promote invasion and motility.
@en
P2093
Adrienne D Cox
James J Fiordalisi
Patricia J Keller
P304
P356
10.1158/0008-5472.CAN-05-3116
P407
P577
2006-03-01T00:00:00Z