The cardenolide UNBS1450 is able to deactivate nuclear factor kappaB-mediated cytoprotective effects in human non-small cell lung cancer cells.
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Digitoxin and a synthetic monosaccharide analog inhibit cell viability in lung cancer cellsReal-time analysis of the effects of toxic, therapeutic and sub-therapeutic concentrations of digitoxin on lung cancer cellsEvaluating the cancer therapeutic potential of cardiac glycosidesDigoxin and other cardiac glycosides inhibit HIF-1alpha synthesis and block tumor growth.Inhibition of Na+/K+-ATPase induces hybrid cell death and enhanced sensitivity to chemotherapy in human glioblastoma cells.SmgGDS regulates cell proliferation, migration, and NF-kappaB transcriptional activity in non-small cell lung carcinoma.Trichothecin induces cell death in NF-κB constitutively activated human cancer cells via inhibition of IKKβ phosphorylation.Cardenolide-induced lysosomal membrane permeabilization demonstrates therapeutic benefits in experimental human non-small cell lung cancers.Toxicarioside A inhibits SGC-7901 proliferation, migration and invasion via NF-κB/bFGF signaling.Characterization of Cardiac Glycoside Natural Products as Potent Inhibitors of DNA Double-Strand Break Repair by a Whole-Cell Double Immunofluorescence Assay.The sodium pump alpha1 subunit as a potential target to combat apoptosis-resistant glioblastomas.UNBS5162, a novel naphthalimide that decreases CXCL chemokine expression in experimental prostate cancersEndogenous and exogenous cardiac glycosides: their roles in hypertension, salt metabolism, and cell growth.Digitoxin as an anticancer agent with selectivity for cancer cells: possible mechanisms involved.Digitoxin induces apoptosis in cancer cells by inhibiting nuclear factor of activated T-cells-driven c-MYC expression.Development of potent small-molecule inhibitors to drug the undruggable steroid receptor coactivator-3.The sodium pump and cardiotonic steroids-induced signal transduction protein kinases and calcium-signaling microdomain in regulation of transporter trafficking.A role for ion channels in perivascular glioma invasion.Novel anti-cancer compounds for developing combinatorial therapies to target anoikis-resistant tumors.Modulators of Na/K-ATPase: a patent review.Anticancer steroids: linking natural and semi-synthetic compounds.Cardiac glycosides in cancer therapy: from preclinical investigations towards clinical trials.Calotropis procera extract induces apoptosis and cell cycle arrest at G2/M phase in human skin melanoma (SK-MEL-2) cells.Urgineaglyceride A: a new monoacylglycerol from the Egyptian Drimia maritima bulbs.Na/K Pump and Beyond: Na/K-ATPase as a Modulator of Apoptosis and Autophagy.Targeting the alpha 1 subunit of the sodium pump to combat glioblastoma cells.The alpha1 subunit of the sodium pump could represent a novel target to combat non-small cell lung cancers."The Lower Threshold" phenomenon in tumor cells toward endogenous digitalis-like compounds: Responsible for tumorigenesis?Cell type-dependent ROS and mitophagy response leads to apoptosis or necroptosis in neuroblastoma.Cardiac Glycoside Glucoevatromonoside Induces Cancer Type-Specific Cell Death.Effects of digoxin on cell cycle, apoptosis and NF-κB pathway in Burkitt's lymphoma cells and animal model.
P2860
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P2860
The cardenolide UNBS1450 is able to deactivate nuclear factor kappaB-mediated cytoprotective effects in human non-small cell lung cancer cells.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
The cardenolide UNBS1450 is ab ...... -small cell lung cancer cells.
@en
type
label
The cardenolide UNBS1450 is ab ...... -small cell lung cancer cells.
@en
prefLabel
The cardenolide UNBS1450 is ab ...... -small cell lung cancer cells.
@en
P2093
P1476
The cardenolide UNBS1450 is ab ...... -small cell lung cancer cells.
@en
P2093
Anne Op De Beeck
Eric Van Quaquebeke
Francis Darro
Janique Dewelle
Robert Kiss
Tatjana Mijatovic
P304
P356
10.1158/1535-7163.MCT-05-0367
P577
2006-02-01T00:00:00Z