Small ubiquitin-like modifier (SUMO) modification of natively unfolded proteins tau and alpha-synuclein.
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Sumoylation in Synaptic Function and DysfunctionSUMOylation: Novel Neuroprotective Approach for Alzheimer's Disease?Tau and tauopathiesThe Synaptic Function of α-SynucleinTau physiology and pathomechanisms in frontotemporal lobar degenerationSynthetic Proteins and Peptides for the Direct Interrogation of α-Synuclein Posttranslational ModificationsNF-κB repression by PIAS3 mediated RelA SUMOylationGamma-synuclein as a marker of retinal ganglion cellsZebrafish models of TauopathyIs Transthyretin a Regulator of Ubc9 SUMOylation?Glial contributions to neurodegeneration in tauopathies.A novel method for high accuracy sumoylation site prediction from protein sequencesRibosylation rapidly induces alpha-synuclein to form highly cytotoxic molten globules of advanced glycation end products.SUMO3 modification accelerates the aggregation of ALS-linked SOD1 mutants.A Plastid Protein That Evolved from Ubiquitin and Is Required for Apicoplast Protein Import in Toxoplasma gondii.Relationship between tau pathology and neuroinflammation in Alzheimer's disease.Lysosomes and α-synuclein form a dangerous duet leading to neuronal cell death.Protein tau: prime cause of synaptic and neuronal degeneration in Alzheimer's disease.Neuronal SUMOylation: mechanisms, physiology, and roles in neuronal dysfunction.Keratin hypersumoylation alters filament dynamics and is a marker for human liver disease and keratin mutation.SUMO-1 modification on K166 of polyQ-expanded ataxin-3 strengthens its stability and increases its cytotoxicity.SUMOylation at K340 inhibits tau degradation through deregulating its phosphorylation and ubiquitination.Regulation of synaptic plasticity and cognition by SUMO in normal physiology and Alzheimer's disease.Prokaryotic ubiquitin-like ThiS fusion enhances the heterologous protein overexpression and aggregation in Escherichia coli.Alpha-synuclein function and dysfunction on cellular membranes.Axotrophin/MARCH7 acts as an E3 ubiquitin ligase and ubiquitinates tau protein in vitro impairing microtubule binding.Proteasome inhibition induces α-synuclein SUMOylation and aggregate formation.Sumoylation inhibits alpha-synuclein aggregation and toxicity.Parental binge alcohol abuse alters F1 generation hypothalamic gene expression in the absence of direct fetal alcohol exposure.Profiles of SUMO and ubiquitin conjugation in an Alzheimer's disease modelSUMO proteomics to decipher the SUMO-modified proteome regulated by various diseases.SUMOhunt: Combining Spatial Staging between Lysine and SUMO with Random Forests to Predict SUMOylation.Systematic comparison of the effects of alpha-synuclein mutations on its oligomerization and aggregation.SUMO1 promotes Aβ production via the modulation of autophagyThe many faces of tauTau Hyperphosphorylation and Oxidative Stress, a Critical Vicious Circle in Neurodegenerative Tauopathies?The Human Tau Interactome: Binding to the Ribonucleoproteome, and Impaired Binding of the Proline-to-Leucine Mutant at Position 301 (P301L) to Chaperones and the Proteasome.The yeast homologue of the microtubule-associated protein Lis1 interacts with the sumoylation machinery and a SUMO-targeted ubiquitin ligase.Effects of Serine 129 Phosphorylation on α-Synuclein Aggregation, Membrane Association, and Internalization.Divergent signaling via SUMO modification: potential for CFTR modulation.
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P2860
Small ubiquitin-like modifier (SUMO) modification of natively unfolded proteins tau and alpha-synuclein.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Small ubiquitin-like modifier ...... teins tau and alpha-synuclein.
@en
type
label
Small ubiquitin-like modifier ...... teins tau and alpha-synuclein.
@en
prefLabel
Small ubiquitin-like modifier ...... teins tau and alpha-synuclein.
@en
P2860
P356
P1476
Small ubiquitin-like modifier ...... teins tau and alpha-synuclein.
@en
P2093
Paul E Fraser
Véronique Dorval
P2860
P304
P356
10.1074/JBC.M510127200
P407
P577
2006-02-07T00:00:00Z