The epidermal growth factor receptor (EGFR)-S442F mutant displays increased affinity for neuregulin-2beta and agonist-independent coupling with downstream signalling events.
about
Interactions among genes in the ErbB-Neuregulin signalling network are associated with increased susceptibility to schizophreniaEGFR ligands exhibit functional differences in models of paracrine and autocrine signalingsZIP, an alternative splice variant of ZIP, antagonizes transcription repression and growth inhibition by ZIPHigh-throughput de novo screening of receptor agonists with an automated single-cell analysis and isolation system.Mutational activation of ErbB family receptor tyrosine kinases: insights into mechanisms of signal transduction and tumorigenesis.Rational optimization of a bispecific ligand trap targeting EGF receptor family ligands.Altered EGFR localization and degradation in human breast cancer cells with an amphiregulin/EGFR autocrine loop.Functional selectivity of EGF family peptide growth factors: implications for cancer.The Q43L mutant of neuregulin 2β is a pan-ErbB receptor antagonist.Epiregulin: roles in normal physiology and cancerInter-conversion of neuregulin2 full and partial agonists for ErbB4.Ligand-based receptor tyrosine kinase partial agonists: New paradigm for cancer drug discovery?
P2860
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P2860
The epidermal growth factor receptor (EGFR)-S442F mutant displays increased affinity for neuregulin-2beta and agonist-independent coupling with downstream signalling events.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
The epidermal growth factor re ...... downstream signalling events.
@en
type
label
The epidermal growth factor re ...... downstream signalling events.
@en
prefLabel
The epidermal growth factor re ...... downstream signalling events.
@en
P2093
P2860
P356
P1433
P1476
The epidermal growth factor re ...... downstream signalling events.
@en
P2093
David J Riese
Jennifer L Gilmore
Richard M Gallo
P2860
P356
10.1042/BJ20051687
P407
P577
2006-05-01T00:00:00Z