The epidermal growth factor receptor couples transforming growth factor-alpha, heparin-binding epidermal growth factor-like factor, and amphiregulin to Neu, ErbB-3, and ErbB-4
about
Neuregulin-4: a novel growth factor that acts through the ErbB-4 receptor tyrosine kinaseInteraction between protein tyrosine phosphatase and protein tyrosine kinase is involved in androgen-promoted growth of human prostate cancer cellsUnique carboxyl-terminal sequences of wild type and alternatively spliced variant forms of transforming growth factor-alpha precursors mediate specific interactions with ErbB4 and ErbB2Activation of HER4 by heparin-binding EGF-like growth factor stimulates chemotaxis but not proliferationEpidermal growth factor and betacellulin mediate signal transduction through co-expressed ErbB2 and ErbB3 receptorsDefects in pathfinding by cranial neural crest cells in mice lacking the neuregulin receptor ErbB4Activation of ErbB4 by the bifunctional epidermal growth factor family hormone epiregulin is regulated by ErbB2ErbB expression: the mouse inner ear and maturation of the mitogenic response to heregulin.Dermatitis due to epiregulin deficiency and a critical role of epiregulin in immune-related responses of keratinocyte and macrophage.TGF-alpha expression as a potential biomarker of risk within the normal-appearing colorectal mucosa of patients with and without incident sporadic adenoma.Glial-neuronal interactions in the neuroendocrine control of mammalian puberty: facilitatory effects of gonadal steroids.Betacellulin induces increased retinal vascular permeability in miceActivation of the Ras/mitogen-activated protein kinase pathway by kinase-defective epidermal growth factor receptors results in cell survival but not proliferation.Differential endocytic routing of homo- and hetero-dimeric ErbB tyrosine kinases confers signaling superiority to receptor heterodimers.The acute environment, rather than T cell subset pre-commitment, regulates expression of the human T cell cytokine amphiregulinExtracellular domains drive homo- but not hetero-dimerization of erbB receptorsContribution of glial-neuronal interactions to the neuroendocrine control of female puberty.Defective valvulogenesis in HB-EGF and TACE-null mice is associated with aberrant BMP signaling.Differential distribution of erbB receptors in human glioblastoma multiforme: expression of erbB3 in CD133-positive putative cancer stem cells.NEU overexpression in the furan rat model of cholangiocarcinogenesis compared with biliary ductal cell hyperplasia.Cellular responses to EGFR inhibitors and their relevance to cancer therapy.Rhomboid domain containing 1 promotes colorectal cancer growth through activation of the EGFR signalling pathway.Removal of the membrane-anchoring domain of epidermal growth factor leads to intracrine signaling and disruption of mammary epithelial cell organization.EGF and amphiregulin differentially regulate Cbl recruitment to endosomes and EGF receptor fate.ErbB2 expression increases the spectrum and potency of ligand-mediated signal transduction through ErbB4.Differential regulation of cell proliferation and protease secretion by epidermal growth factor and amphiregulin in tumoral versus normal breast epithelial cellsSystem properties of ErbB receptor signaling for the understanding of cancer progression.Roles of transforming growth factor-alpha in mammary development and disease.The Q43L mutant of neuregulin 2β is a pan-ErbB receptor antagonist.ErbB family receptor inhibitors as therapeutic agents in breast cancer: current status and future clinical perspective.HER2-family signalling mechanisms, clinical implications and targeting in breast cancer.Exocrine Gland Morphogenesis: Insights into the Role of Amphiregulin from Development to Disease.Helicobacter pylori upregulates expression of epidermal growth factor-related peptides, but inhibits their proliferative effect in MKN 28 gastric mucosal cells.EGF-independent activation of cell-surface EGF receptors harboring mutations found in gefitinib-sensitive lung cancer.The epidermal growth factor receptor (EGFR)-S442F mutant displays increased affinity for neuregulin-2beta and agonist-independent coupling with downstream signalling events.Phe45 of NRG2beta is critical for the affinity of NRG2beta for ErbB4 and for potent stimulation of ErbB4 signaling by NRG2beta*.The tumor-specific de2-7 epidermal growth factor receptor (EGFR) promotes cells survival and heterodimerizes with the wild-type EGFR.Activation of STAT5 triggers proliferation and contributes to anti-apoptotic signalling mediated by the oncogenic Xmrk kinase.The transmembrane heregulin precursor is functionally active.Identification of an alternatively spliced mRNA transcript of human betacellulin lacking the C-loop of the EGF motif and the transmembrane domain.
P2860
146de27e49ed1e891e8210032bf0709e3e3e255e1e90ace40d9121527b28d61b76123c280012fc5934b35b449653879de8409c213090dec1eddb4980459d9f29883a50c0e24489165527e028347880514c66fad06a97314b8dda842b65651ca1043b70c07dd9aaa17fddb71c7a3f004ad2050371a1fdd91b7f2dbd61c7f84e3dd758f9ef80a3e3912a9f3018960804d40be6acd1b561a1d588e920a529a466f19f585e95715aa616e6e1aafd4fd589e255052ccbe9308ce64f0f6af2fa058c066d14f130a85769a5
P248
Q22009917-9D316532-8CEE-4E53-895E-AC96A163E47FQ22254244-DAFC1924-1E3A-470F-A17E-7DD3690B80D1Q22254700-D7A7EF32-9FC1-40EC-83FC-51480174FDF3Q24318527-EA2851C9-F3F5-4A90-A144-4D8AF658F50EQ24532786-9DAED786-84B7-4176-85E7-1CE243E2BF1BQ28506344-40C3E4EB-7062-4EA8-ABB7-6ACAE6C6AF65Q28609160-D3621100-6695-4CD1-8CC0-9D19627E6019Q30473444-026DC366-EA74-4A72-869C-BC7CB01A5930Q31111797-0F00E055-21B8-45BF-9A9F-109A6F8B43CAQ33397653-9AD1735E-17B5-4098-95EB-DC2CDF4B3B45Q33714949-F312872F-9F04-4254-BDEF-736A863BCB33Q33728352-76A26428-64A6-448B-A82A-10D769292B1DQ33781714-1C965A7B-8FCF-480B-9F85-772A183A821CQ33888963-87832C62-6859-4F40-9AA4-3B52BF19D82FQ34312117-250C2230-6833-4C87-ADCA-0DFBBF0CDB26Q34488149-06A7FCD7-4B6F-41DA-9B89-C46AFACFD54FQ34678739-56D8DFD5-17F2-466A-AAF4-E94CCE07A897Q35032897-DC59BAF0-7A06-402B-81CE-A629EFD16D99Q35214798-7C95808E-E9FB-4B9F-88EE-C8D979AB7310Q35764997-7641C0E5-2EEF-4077-B3FC-C33A7010A8ECQ36003118-60E4F51C-48BA-4F5C-91DA-039F58CBA673Q36030023-589635CA-61FE-4B2E-9035-71225609CF25Q36256364-7E32A807-1DDD-492C-B147-E33F7D8A53F9Q36426553-DE596F5D-D5F9-48F4-B7C8-374B8D7B2325Q36490427-B8621603-F3A6-4E7C-8558-903087326207Q36622861-BF34C994-2B5D-4D4C-B536-8D0963672701Q36716462-79CE7055-8513-41E0-BB55-0CDF7D5FA5AAQ37037476-22F07225-452A-4D33-AEBF-95F0CA333001Q37650953-B4BD0198-7CFA-4EFD-895E-18E4C7D73C6AQ37970020-698EC8A6-F5E4-46C1-8753-BE33BBA5573DQ38301236-D5B75574-71D5-40A6-A0B5-C30AE3868586Q39358786-E95B97A1-167E-47CE-9B17-48809ED6C746Q39802405-DE7655DF-11E4-41F1-B380-89A60B712F67Q40235641-EF3B7E73-1D08-49F5-8428-86F1A065ABD3Q40323538-B8EF6FDD-1F8D-4E24-8B20-1BBCFC013A8CQ40341840-BAD93DA1-099C-4693-960F-69682810FA86Q40541045-B7A94431-9FF4-44FD-A89B-E64C92293286Q40744434-FE7C050C-E53A-4A1F-AD17-181616446FEFQ40787351-543D154C-588D-445B-A6F4-18E9C152EB79Q40808585-A430E1FC-61B7-478A-8EB9-2FFDEADAF346
P2860
The epidermal growth factor receptor couples transforming growth factor-alpha, heparin-binding epidermal growth factor-like factor, and amphiregulin to Neu, ErbB-3, and ErbB-4
description
1996 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 1996
@ast
im August 1996 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1996/08/16)
@sk
vědecký článek publikovaný v roce 1996
@cs
wetenschappelijk artikel (gepubliceerd op 1996/08/16)
@nl
наукова стаття, опублікована в серпні 1996
@uk
name
The epidermal growth factor re ...... lin to Neu, ErbB-3, and ErbB-4
@ast
The epidermal growth factor re ...... lin to Neu, ErbB-3, and ErbB-4
@en
The epidermal growth factor re ...... lin to Neu, ErbB-3, and ErbB-4
@nl
type
label
The epidermal growth factor re ...... lin to Neu, ErbB-3, and ErbB-4
@ast
The epidermal growth factor re ...... lin to Neu, ErbB-3, and ErbB-4
@en
The epidermal growth factor re ...... lin to Neu, ErbB-3, and ErbB-4
@nl
prefLabel
The epidermal growth factor re ...... lin to Neu, ErbB-3, and ErbB-4
@ast
The epidermal growth factor re ...... lin to Neu, ErbB-3, and ErbB-4
@en
The epidermal growth factor re ...... lin to Neu, ErbB-3, and ErbB-4
@nl
P2093
P921
P356
P1476
The epidermal growth factor re ...... lin to Neu, ErbB-3, and ErbB-4
@en
P2093
D. F. Stern
D. J. Riese
G. D. Plowman
M. Klagsbrun
S. Buckley
P304
20047–20052
P356
10.1074/JBC.271.33.20047
P407
P577
1996-08-16T00:00:00Z