The current status of attempts to predict species differences in drug metabolism.
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Evolution of a major drug metabolizing enzyme defect in the domestic cat and other felidae: phylogenetic timing and the role of hypercarnivoryInnovative drugs to treat depression: did animal models fail to be predictive or did clinical trials fail to detect effects?Antiretrovirals induce endothelial dysfunction via an oxidant-dependent pathway and promote neointimal hyperplasiaCytochrome P450 and xenobiotic receptor humanized mice.Species differences in pharmacokinetics and drug teratogenesis.Cardiotoxicity of vasodilators and positive inotropic/vasodilating drugs in dogs: an overview.Metabolism of 17alpha-hydroxyprogesterone caproate by hepatic and placental microsomes of human and baboons.Humanized mouse lines and their application for prediction of human drug metabolism and toxicological risk assessmentSubstituted diphenyl ethers as a broad-spectrum platform for the development of chemotherapeutics for the treatment of tularaemiaIn vivo modeling of human liver for pharmacological study using humanized mouse.A human hepatocyte-bearing mouse: an animal model to predict drug metabolism and effectiveness in humansCurrent challenges and controversies in drug-induced liver injury.Disposition of xenobiotics: species differences.Comparative metabolism in food-producing animals: programs sponsored by the Center for Veterinary Medicine.Extrapolation from animals to man: predictions, pitfalls and perspectives.Prediction of human pharmacokinetics--evaluation of methods for prediction of hepatic metabolic clearance.Evolutionary biology, animal behavior, fourth-dimensional space, and the raison d'etre of drug metabolism and pharmacokinetics.First-time-in-human dose selection: allometric thoughts and perspectives.Biokinetics and biokinetic models in risk assessment.Recombination activating gene-2null severe combined immunodeficient pigs and mice engraft human induced pluripotent stem cells differently.Formation of reactive metabolites of phenacetin in humans and rats.Identification of interspecific differences in phase II reactions: determination of metabolites in the urine of 16 mammalian species exposed to environmental pyrene.Animal models of pancreatic cancer for drug research.ADME
P2860
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P2860
The current status of attempts to predict species differences in drug metabolism.
description
1981 nî lūn-bûn
@nan
1981年の論文
@ja
1981年論文
@yue
1981年論文
@zh-hant
1981年論文
@zh-hk
1981年論文
@zh-mo
1981年論文
@zh-tw
1981年论文
@wuu
1981年论文
@zh
1981年论文
@zh-cn
name
The current status of attempts to predict species differences in drug metabolism.
@en
type
label
The current status of attempts to predict species differences in drug metabolism.
@en
prefLabel
The current status of attempts to predict species differences in drug metabolism.
@en
P2860
P1476
The current status of attempts to predict species differences in drug metabolism.
@en
P2093
Caldwell J
P2860
P304
P356
10.3109/03602538108994030
P407
P577
1981-01-01T00:00:00Z