KLF5 promotes cell proliferation and tumorigenesis through gene regulation and the TSU-Pr1 human bladder cancer cell line.
about
Proteasomal degradation of the KLF5 transcription factor through a ubiquitin-independent pathwayMammalian Krüppel-like factors in health and diseasesThe diverse functions of Krüppel-like factors 4 and 5 in epithelial biology and pathobiologyEvasion of anti-growth signaling: A key step in tumorigenesis and potential target for treatment and prophylaxis by natural compounds.Potential prognostic, diagnostic and therapeutic markers for human gastric cancerFBW7-mediated ubiquitination and degradation of KLF5The double life of KLF5: Opposing roles in regulation of gene-expression, cellular function, and transformationFBXW7 mutations typically found in human cancers are distinct from null alleles and disrupt lung developmentInvestigation of the atypical FBXW7 mutation spectrum in human tumours by conditional expression of a heterozygous propellor tip missense allele in the mouse intestinesIdentification of novel small-molecule compounds that inhibit the proproliferative Kruppel-like factor 5 in colorectal cancer cells by high-throughput screeningThe induction of KLF5 transcription factor by progesterone contributes to progesterone-induced breast cancer cell proliferation and dedifferentiation.Perfusion of veins at arterial pressure increases the expression of KLF5 and cell cycle genes in smooth muscle cellsThe Fbw7/human CDC4 tumor suppressor targets proproliferative factor KLF5 for ubiquitination and degradation through multiple phosphodegron motifs.Kruppel-like factor 5 is not required for K-RasG12D lung tumorigenesis, but represses ABCG2 expression and is associated with better disease-specific survival.Curcumin promotes KLF5 proteasome degradation through downregulating YAP/TAZ in bladder cancer cells.WWOX suppresses KLF5 expression and breast cancer cell growthInterruption of KLF5 acetylation converts its function from tumor suppressor to tumor promoter in prostate cancer cells.Klf5 deletion promotes Pten deletion-initiated luminal-type mouse prostate tumors through multiple oncogenic signaling pathwaysKrüppel-like factor 5 mediates cellular transformation during oncogenic KRAS-induced intestinal tumorigenesisDifferent expression patterns and functions of acetylated and unacetylated Klf5 in the proliferation and differentiation of prostatic epithelial cells.Krüppel-like factor 5 contributes to pulmonary artery smooth muscle proliferation and resistance to apoptosis in human pulmonary arterial hypertension.Ataxin-3 like (ATXN3L), a member of the Josephin family of deubiquitinating enzymes, promotes breast cancer proliferation by deubiquitinating Krüppel-like factor 5 (KLF5).Anti-tumor effects of fibroblast growth factor-binding protein (FGF-BP) knockdown in colon carcinoma.BAP1 promotes breast cancer cell proliferation and metastasis by deubiquitinating KLF5.Tumor suppressor functions of FBW7 in cancer development and progression.The interplay between TEAD4 and KLF5 promotes breast cancer partially through inhibiting the transcription of p27Kip1.Krüppel-Like Factor 5 Promotes Epithelial Proliferation and DNA Damage Repair in the Intestine of Irradiated Mice.ML264, A Novel Small-Molecule Compound That Potently Inhibits Growth of Colorectal Cancer.Beyond proliferation: KLF5 promotes angiogenesis of bladder cancer through directly regulating VEGFA transcription.Oestrogen causes degradation of KLF5 by inducing the E3 ubiquitin ligase EFP in ER-positive breast cancer cells.Kruppel-like factor 5 transcription factor promotes microsomal prostaglandin E2 synthase 1 gene transcription in breast cancerKLF5 promotes breast cell survival partially through fibroblast growth factor-binding protein 1-pERK-mediated dual specificity MKP-1 protein phosphorylation and stabilizationExpression and Function of Kruppel Like-Factors (KLF) in Carcinogenesis.KLF5 activates microRNA 200 transcription to maintain epithelial characteristics and prevent induced epithelial-mesenchymal transition in epithelial cells.Krüppel-like factors 4 and 5: unity in diversityKruppel-like factors and vascular inflammation: implications for atherosclerosis.Molecular mechanisms of biomaterial-driven osteogenic differentiation in human mesenchymal stromal cells.Role of Krüppel-like factors in cancer stem cells.Kruppel-like factor 5 is required for formation and differentiation of the bladder urotheliumKrüppel-like factor 5 is essential for maintenance of barrier function in mouse colon.
P2860
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P2860
KLF5 promotes cell proliferation and tumorigenesis through gene regulation and the TSU-Pr1 human bladder cancer cell line.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
KLF5 promotes cell proliferati ...... uman bladder cancer cell line.
@en
type
label
KLF5 promotes cell proliferati ...... uman bladder cancer cell line.
@en
prefLabel
KLF5 promotes cell proliferati ...... uman bladder cancer cell line.
@en
P2093
P50
P356
P1476
KLF5 promotes cell proliferati ...... uman bladder cancer cell line.
@en
P2093
Jonathan W Simons
Kristen B Otto
Michael S Benjamin
Xiaohong Cheng
Yongde Bao
Zhongmei Zhou
P304
P356
10.1002/IJC.21533
P577
2006-03-01T00:00:00Z