Krüppel-like factor 5 mediates cellular transformation during oncogenic KRAS-induced intestinal tumorigenesis
about
Bronchial epithelium-derived IL-8 and RANTES increased bronchial smooth muscle cell migration and proliferation by Krüppel-like factor 5 in areca nut-mediated airway remodelingMammalian Krüppel-like factors in health and diseasesCell Fusion in the War on Cancer: A Perspective on the Inception of MalignancyEvasion of anti-growth signaling: A key step in tumorigenesis and potential target for treatment and prophylaxis by natural compounds.The double life of KLF5: Opposing roles in regulation of gene-expression, cellular function, and transformationDUSP10 regulates intestinal epithelial cell growth and colorectal tumorigenesis.Identification of novel small-molecule compounds that inhibit the proproliferative Kruppel-like factor 5 in colorectal cancer cells by high-throughput screeningApoptosis induction by 13-acetoxyrolandrolide through the mitochondrial intrinsic pathway.Krüppel-like factor 5 is a crucial mediator of intestinal tumorigenesis in mice harboring combined ApcMin and KRASV12 mutations.KLF4 is regulated by RAS/RAF/MEK/ERK signaling through E2F1 and promotes melanoma cell growth.Identification of small-molecule inhibitors of the colorectal cancer oncogene Krüppel-like factor 5 expression by ultrahigh-throughput screeningKruppel-like factor 5 is not required for K-RasG12D lung tumorigenesis, but represses ABCG2 expression and is associated with better disease-specific survival.A small ubiquitin-related modifier-interacting motif functions as the transcriptional activation domain of Krüppel-like factor 4.Krüppel-like factor 5 protects against murine colitis and activates JAK-STAT signaling in vivo.Genome-wide screening for genetic alterations in esophageal cancer by aCGH identifies 11q13 amplification oncogenes associated with nodal metastasisCharacterization of HPV and host genome interactions in primary head and neck cancers.Interruption of KLF5 acetylation converts its function from tumor suppressor to tumor promoter in prostate cancer cells.Krüppel-like factor 5 protects against dextran sulfate sodium-induced colonic injury in mice by promoting epithelial repairKlf5 deletion promotes Pten deletion-initiated luminal-type mouse prostate tumors through multiple oncogenic signaling pathwaysHelicobacter pylori promotes the expression of Krüppel-like factor 5, a mediator of carcinogenesis, in vitro and in vivo.Different expression patterns and functions of acetylated and unacetylated Klf5 in the proliferation and differentiation of prostatic epithelial cells.Krüpple-like factor 5 is required for proper maintenance of adult intestinal crypt cellular proliferation.Integrative genomic and functional profiling of the pancreatic cancer genome.Krüppel-like factor 5 is essential for proliferation and survival of mouse intestinal epithelial stem cells.Krüppel-like factor 5 is important for maintenance of crypt architecture and barrier function in mouse intestineMutational landscape of mucinous ovarian carcinoma and its neoplastic precursors.Transgenic Expression of Human Lysophosphatidic Acid Receptor LPA2 in Mouse Intestinal Epithelial Cells Induces Intestinal Dysplasia.Krüppel-Like Factor 5 Promotes Epithelial Proliferation and DNA Damage Repair in the Intestine of Irradiated Mice.Oncogenic KRAS signalling promotes the Wnt/β-catenin pathway through LRP6 in colorectal cancer.ML264, A Novel Small-Molecule Compound That Potently Inhibits Growth of Colorectal Cancer.Genetic amplification of the NOTCH modulator LNX2 upregulates the WNT/β-catenin pathway in colorectal cancer.Potential involvement of miR-375 in the premalignant progression of oral squamous cell carcinoma mediated via transcription factor KLF5.New acyclic bis phenylpropanoid and neolignans, from Myristica fragrans Houtt., exhibiting PARP-1 and NF-κB inhibitory effectsThe Pathobiology of Krüppel-like Factors in Colorectal Cancer.Five endometrial cancer risk loci identified through genome-wide association analysis.Oestrogen causes degradation of KLF5 by inducing the E3 ubiquitin ligase EFP in ER-positive breast cancer cells.Jagged1 is the pathological link between Wnt and Notch pathways in colorectal cancerType I insulin-like growth factor receptor induces pulmonary tumorigenesis.Acetylation of KLF5 alters the assembly of p15 transcription factors in transforming growth factor-beta-mediated induction in epithelial cells.Expression and Function of Kruppel Like-Factors (KLF) in Carcinogenesis.
P2860
Q24339334-48C3E14B-C225-47FE-B202-F3CABE91C72BQ24612560-120809D8-DF6D-4B3A-BD92-75C8772F1A91Q26740111-5393D792-BB18-458A-8B75-98B96786FCEAQ26827810-4A51E0DD-63FC-478C-8F1D-71A259187FCBQ27022848-47FD9701-AB6F-4D46-B7C4-63F6B7D79501Q31813071-C29342AB-861F-46C6-9156-21619DBEB456Q33412050-E1FF5932-BE3B-47F8-BB71-4B9A78D56522Q33748016-169BFAD5-D4EE-4AD8-8363-4AB3D93A3D14Q33797492-162E5826-634C-410B-AA54-12E49E368851Q33809921-350D5316-C822-45D0-8675-80C019C9C6F1Q34008343-E1E644DF-C5A7-43DF-95D9-F76979EA254DQ34087027-2FCD9AB8-6D47-4CA0-BBF7-C2CE07180FFEQ34107480-1FEF0681-1E13-473F-A592-4D43B913165FQ34295488-669CE2DE-DB52-4E3F-A9A8-5DA63C35465DQ34326537-5BD1A4DF-FE1E-4D67-9FAC-0408556C7A68Q34442327-6A82C52B-D15C-4C6F-9018-B8A180598E48Q34514009-2C8F8C86-9D45-43F8-97D8-C7B877CCC69CQ34542943-419EB253-A16A-48B9-910C-016D40997355Q34558936-2DA337CB-13C3-485A-A13F-B8627086FAE7Q34571124-06E1D8DF-7A61-4AF9-A6CE-7A085B253CF1Q34766615-5D0E4523-B636-4E74-BD48-DF3C52DD96CDQ34860168-A8ABD8A1-74D4-431D-81A8-4CA4C700A955Q34990981-0886C5D1-AD40-48C4-B98F-071142A14B63Q35027764-245FF83C-6780-4245-A73F-3DDE3363FDD4Q35269425-9C086B81-CA67-4124-BEC6-8D5228881FD8Q35926362-5C8E8F17-F9D1-4831-98F4-56E810DAAD7CQ36002122-4AC59CA8-62F0-443F-85F2-69B86010530FQ36352746-C2C6D47E-ED81-4F8E-8C9F-069CE02CC0BCQ36394050-D32C6517-72A4-4893-90CC-D28DCA14AFE2Q36447499-8477334E-4C7F-400B-903F-EEF49B61DD98Q36509342-DCADCA46-7FF3-449D-9AFB-5FE8D546995DQ36545576-9C0DBF72-907E-42D0-9651-F2ADC10D2C64Q36628651-11DBFBC2-006B-4652-98D6-A611DCA5A78FQ36672289-28345FFC-AF0C-4CE7-9260-7111D1B1E494Q37002930-C2053701-8CAC-4FC2-8439-105044F71CADQ37070467-601E0E55-B87D-4EA4-A755-65252C82099FQ37158989-66C7E363-F4C5-4E67-9538-44F8EE1393C8Q37229930-B178486A-80B2-4513-A3CB-66312E888956Q37258607-3847D7E1-8D56-4929-8A8D-194D8CD42FDCQ37313427-17258178-0DE6-4CF0-85AC-C44C5757C4D1
P2860
Krüppel-like factor 5 mediates cellular transformation during oncogenic KRAS-induced intestinal tumorigenesis
description
2007 nî lūn-bûn
@nan
2007 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Krüppel-like factor 5 mediates ...... duced intestinal tumorigenesis
@ast
Krüppel-like factor 5 mediates ...... duced intestinal tumorigenesis
@en
Krüppel-like factor 5 mediates ...... duced intestinal tumorigenesis
@nl
type
label
Krüppel-like factor 5 mediates ...... duced intestinal tumorigenesis
@ast
Krüppel-like factor 5 mediates ...... duced intestinal tumorigenesis
@en
Krüppel-like factor 5 mediates ...... duced intestinal tumorigenesis
@nl
prefLabel
Krüppel-like factor 5 mediates ...... duced intestinal tumorigenesis
@ast
Krüppel-like factor 5 mediates ...... duced intestinal tumorigenesis
@en
Krüppel-like factor 5 mediates ...... duced intestinal tumorigenesis
@nl
P2093
P2860
P1433
P1476
Krüppel-like factor 5 mediates ...... duced intestinal tumorigenesis
@en
P2093
Agnieszka B Bialkowska
Amr M Ghaleb
Beth B McConnell
Brian A Babbin
Hongmiao Sheng
Jinyi Shao
Mandayam O Nandan
Sylvie Robine
Vincent W Yang
P2860
P304
P356
10.1053/J.GASTRO.2007.10.023
P407
P577
2007-10-17T00:00:00Z