Role for hedgehog signaling in hepatic stellate cell activation and viability. - Wikidata - wikimedia - TriplyDB

Role for hedgehog signaling in hepatic stellate cell activation and viability.

Role for hedgehog signaling in hepatic stellate cell activation and viability.

http://www.wikidata.org/entity/Q40371810

about

Non-alcoholic fatty liver disease: what the clinician needs to know.MicroRNAs in liver fibrosis: Focusing on the interaction with hedgehog signaling Role of Hedgehog Signaling Pathway in NASH Hedgehog Signaling in Pancreatic Fibrosis and Cancer Novel aspects of the liver microenvironment in hepatocellular carcinoma pathogenesis and development Potential role of thymosin Beta 4 in liver fibrosis Hedgehog signaling antagonist promotes regression of both liver fibrosis and hepatocellular carcinoma in a murine model of primary liver cancer Hepatic Hedgehog signaling contributes to the regulation of IGF1 and IGFBP1 serum levels Sonic hedgehog ligand partners with caveolin-1 for intracellular transport Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver Mechanisms of hepatic fibrogenesis Significance of sonic hedgehog signaling after massive hepatectomy in a rat.Loss of pericyte smoothened activity in mice with genetic deficiency of leptin.Significant gene expression differences in histologically "Normal" liver biopsies: Implications for control tissue.Hedgehog pathway activation and epithelial-to-mesenchymal transitions during myofibroblastic transformation of rat hepatic cells in culture and cirrhosis Thymosin beta-4 regulates activation of hepatic stellate cells via hedgehog signaling.Liver zonation: Novel aspects of its regulation and its impact on homeostasis.Hedgehog signaling is critical for normal liver regeneration after partial hepatectomy in mice.Aberrant Hedgehog ligands induce progressive pancreatic fibrosis by paracrine activation of myofibroblasts and ductular cells in transgenic zebrafish.Frequent deregulations in the hedgehog signaling network and cross-talks with the epidermal growth factor receptor pathway involved in cancer progression and targeted therapies.Role for hedgehog pathway in regulating growth and function of invariant NKT cells.Viral factors induce Hedgehog pathway activation in humans with viral hepatitis, cirrhosis, and hepatocellular carcinoma.Principles of liver regeneration and growth homeostasis.Differential effects of arsenic trioxide on chemosensitization in human hepatic tumor and stellate cell lines Gli1 activation and protection against hepatic encephalopathy is suppressed by circulating transforming growth factor β1 in mice.Hepatic stellate cells and astrocytes: Stars of scar formation and tissue repair.Reply: To PMID 24849310.Polymeric nanoparticle-encapsulated hedgehog pathway inhibitor HPI-1 (NanoHHI) inhibits systemic metastases in an orthotopic model of human hepatocellular carcinoma MicroRNA125b-mediated Hedgehog signaling influences liver regeneration by chorionic plate-derived mesenchymal stem cells.Salvianolic acid B-induced microRNA-152 inhibits liver fibrosis by attenuating DNMT1-mediated Patched1 methylation.Hedgehog controls hepatic stellate cell fate by regulating metabolism Macrophage-derived Hedgehog ligands promotes fibrogenic and angiogenic responses in human schistosomiasis mansoni.Transcriptional regulation of stellate cell activation.MicroRNA-378 limits activation of hepatic stellate cells and liver fibrosis by suppressing Gli3 expression.Accumulation of hedgehog-responsive progenitors parallels alcoholic liver disease severity in mice and humans.Signals from dying hepatocytes trigger growth of liver progenitors Hepatic stellate cells in liver development, regeneration, and cancer.Osteopontin is a novel downstream target of SOX9 with diagnostic implications for progression of liver fibrosis in humans.Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans.The adventures of sonic hedgehog in development and repair. II. Sonic hedgehog and liver development, inflammation, and cancer.

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Role for hedgehog signaling in hepatic stellate cell activation and viability.

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Role for hedgehog signaling in hepatic stellate cell activation and viability.

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Role for hedgehog signaling in hepatic stellate cell activation and viability.

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Role for hedgehog signaling in hepatic stellate cell activation and viability.

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Laboratory Investigation

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Role for hedgehog signaling in hepatic stellate cell activation and viability.

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Anna Mae Diehl

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Jason K Sicklick

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Jiawen Huang

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Marcia Bustamante

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Marcos Rojkind

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Marzena Zdanowicz

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Michael S Torbenson

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Steve S Choi

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Terese Camp

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Wei Chen

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P2860

Activating Smoothened mutations in sporadic basal-cell carcinoma

Suppressor of fused regulates Gli activity through a dual binding mechanism

Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Insights into the Pathobiology of Hepatitis C Virus-Associated Cirrhosis

Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

The Hedgehog and Wnt signalling pathways in cancer

Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours

Indian Hedgehog is an antagonist of Wnt signaling in colonic epithelial cell differentiation

Rapid clearance of psoriatic skin lesions induced by topical cyclopamine. A preliminary proof of concept study

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