Glycogen synthase kinase 3beta functions to specify gene-specific, NF-kappaB-dependent transcription.
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Ankrd2 is a modulator of NF-κB-mediated inflammatory responses during muscle differentiationGlycogen synthase kinase-3β is a crucial mediator of signal-induced RelB degradationCARMA1 is required for Akt-mediated NF-kappaB activation in T cells.Upregulation of RGS4 expression by IL-1beta in colonic smooth muscle is enhanced by ERK1/2 and p38 MAPK and inhibited by the PI3K/Akt/GSK3beta pathwayGlycogen synthase kinase-3 (GSK3): inflammation, diseases, and therapeuticsA New alpha5beta1 integrin-dependent survival pathway through GSK3beta activation in leukemic cellsEndoplasmic reticulum stress stimulates p53 expression through NF-κB activationUnlocking mechanisms in interleukin-1β-induced changes in hippocampal neurogenesis--a role for GSK-3β and TLXAkt-dependent regulation of NF-{kappa}B is controlled by mTOR and Raptor in association with IKK.Inhibition of GSK3β-mediated BACE1 expression reduces Alzheimer-associated phenotypes.Primers on molecular pathways. The glycogen synthase kinase-3betaER stress in Alzheimer's disease: a novel neuronal trigger for inflammation and Alzheimer's pathology.Inhibition of glycogen synthase kinase 3beta (GSK3beta) decreases inflammatory responses in brain endothelial cellsHSYA alleviates secondary neuronal death through attenuating oxidative stress, inflammatory response, and neural apoptosis in SD rat spinal cord compression injuryInnate and adaptive immune responses regulated by glycogen synthase kinase-3 (GSK3).Her2 activates NF-kappaB and induces invasion through the canonical pathway involving IKKalpha.GSK-3 represses growth factor-inducible genes by inhibiting NF-kappaB in quiescent cells.Inhaled aerosolized insulin ameliorates hyperglycemia-induced inflammatory responses in the lungs in an experimental model of acute lung injury.Increased mitochondrial calcium sensitivity and abnormal expression of innate immunity genes precede dopaminergic defects in Pink1-deficient mice.Glycogen synthase kinase-3 regulates inflammatory tolerance in astrocytes.PI3K-dependent GSK3ß(Ser9)-phosphorylation is implicated in the intestinal epithelial cell wound-healing response.Akt pathway is hypoactivated by synergistic actions of diabetes mellitus and hypercholesterolemia resulting in advanced coronary artery disease.Interference with intraepithelial TNF-α signaling inhibits CD8(+) T-cell-mediated lung injury in influenza infectionA screen for transcription factor targets of glycogen synthase kinase-3 highlights an inverse correlation of NFκB and androgen receptor signaling in prostate cancerGlycogen synthase kinase-3β inactivation inhibits tumor necrosis factor-α production in microglia by modulating nuclear factor κB and MLK3/JNK signaling cascadesGlycogen synthase kinase-3beta (GSK3beta) inhibition suppresses the inflammatory response to Francisella infection and protects against tularemia in miceCG0009, a novel glycogen synthase kinase 3 inhibitor, induces cell death through cyclin D1 depletion in breast cancer cells.Ibuprofen inhibits activation of nuclear {beta}-catenin in human colon adenomas and induces the phosphorylation of GSK-3{beta}.The paradoxical pro- and anti-apoptotic actions of GSK3 in the intrinsic and extrinsic apoptosis signaling pathways.NF-κB addiction and its role in cancer: 'one size does not fit all'.A GSK-3-mediated transcriptional network maintains repression of immediate early genes in quiescent cells.Canonical and non-canonical NF-κB signaling promotes breast cancer tumor-initiating cellsFine-tuning of NFκB by glycogen synthase kinase 3β directs the fate of glomerular podocytes upon injury.Tumor necrosis factor induces GSK3 kinase-mediated cross-tolerance to endotoxin in macrophages.Inhibition of glycogen synthase kinase-3 activity leads to epigenetic silencing of nuclear factor kappaB target genes and induction of apoptosis in chronic lymphocytic leukemia B cellsResolution of the nuclear localization mechanism of glycogen synthase kinase-3: functional effects in apoptosis.Inhibition of glycogen synthase kinase-3 beta induces apoptosis and mitotic catastrophe by disrupting centrosome regulation in cancer cells.The pro-survival pathways of mTOR and protein kinase B target glycogen synthase kinase-3beta and nuclear factor-kappaB to foster endogenous microglial cell protection.NF-κB signaling is essential for resistance to heat stress-induced early stage apoptosis in human umbilical vein endothelial cellsProtein kinase R-like endoplasmic reticulum kinase and glycogen synthase kinase-3α/β regulate foam cell formation.
P2860
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P2860
Glycogen synthase kinase 3beta functions to specify gene-specific, NF-kappaB-dependent transcription.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Glycogen synthase kinase 3beta ...... appaB-dependent transcription.
@en
type
label
Glycogen synthase kinase 3beta ...... appaB-dependent transcription.
@en
prefLabel
Glycogen synthase kinase 3beta ...... appaB-dependent transcription.
@en
P2093
P2860
P1476
Glycogen synthase kinase 3beta ...... appaB-dependent transcription.
@en
P2093
Albert S Baldwin
Kris A Steinbrecher
Patricia C Cogswell
Willie Wilson
P2860
P304
P356
10.1128/MCB.25.19.8444-8455.2005
P407
P577
2005-10-01T00:00:00Z