Perlecan from human epithelial cells is a hybrid heparan/chondroitin/keratan sulfate proteoglycan.
about
Progranulin directly binds to the CRD2 and CRD3 of TNFR extracellular domainsDynamic expression patterns of ECM molecules in the developing mouse olfactory pathwayMyeloperoxidase-derived oxidants selectively disrupt the protein core of the heparan sulfate proteoglycan perlecan.Soluble perlecan domain I enhances vascular endothelial growth factor-165 activity and receptor phosphorylation in human bone marrow endothelial cells.Peroxynitrite modifies the structure and function of the extracellular matrix proteoglycan perlecan by reaction with both the protein core and the heparan sulfate chainsSulfated glycosaminoglycans control the extracellular trafficking and the activity of the metalloprotease inhibitor TIMP-3.Proteoglycans in Normal and Healing Skin.Three TNFR-binding domains of PGRN act independently in inhibition of TNF-alpha binding and activity.Heparan sulfate proteoglycans: a GAGgle of skeletal-hematopoietic regulators.The role of vascular-derived perlecan in modulating cell adhesion, proliferation and growth factor signaling.Heparan sulfates mediate the interaction between platelet endothelial cell adhesion molecule-1 (PECAM-1) and the Gαq/11 subunits of heterotrimeric G proteins.Mechanisms and consequences of oxidative damage to extracellular matrix.Recombinant production of proteoglycans and their bioactive domains.Oxidation and modification of extracellular matrix and its role in disease.A solid-phase assay for studying direct binding of progranulin to TNFR and progranulin antagonism of TNF/TNFR interactions.Ablation of Perlecan Domain 1 Heparan Sulfate Reduces Progressive Cartilage Degradation, Synovitis, and Osteophyte Size in a Preclinical Model of Posttraumatic Osteoarthritis.Glycosaminoglycan and Proteoglycan-Based Biomaterials: Current Trends and Future Perspectives.Recombinant Domain V of Human Perlecan Is a Bioactive Vascular Proteoglycan.Keratan Sulphate, a complex Glycosaminoglycan with Unique Functional Capability.The heparan sulphate deficient Hspg2 exon 3 null mouse displays reduced deposition of TGF-β1 in skin compared to C57BL/6 wild type mice.Perlecan heparan sulfate deficiency impairs pulmonary vascular development and attenuates hypoxic pulmonary hypertension.
P2860
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P2860
Perlecan from human epithelial cells is a hybrid heparan/chondroitin/keratan sulfate proteoglycan.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Perlecan from human epithelial ...... /keratan sulfate proteoglycan.
@en
type
label
Perlecan from human epithelial ...... /keratan sulfate proteoglycan.
@en
prefLabel
Perlecan from human epithelial ...... /keratan sulfate proteoglycan.
@en
P2860
P50
P1433
P1476
Perlecan from human epithelial ...... n/keratan sulfate proteoglycan
@en
P2093
P2860
P304
P356
10.1016/J.FEBSLET.2005.07.090
P407
P577
2005-09-01T00:00:00Z