Donepezil-tacrine hybrid related derivatives as new dual binding site inhibitors of AChE.
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An overview on therapeutics attenuating amyloid β level in Alzheimer's disease: targeting neurotransmission, inflammation, oxidative stress and enhanced cholesterol levelsQSAR analysis on tacrine-related acetylcholinesterase inhibitors.Acetylcholinesterase inhibitors: pharmacology and toxicology.Novel Triazole-Quinoline Derivatives as Selective Dual Binding Site Acetylcholinesterase Inhibitors.Inhibition of acetylcholinesterase by two genistein derivatives: kinetic analysis, molecular docking and molecular dynamics simulationTargeting acetylcholinesterase to treat neurodegeneration.Potent beta-amyloid modulators.A review on cholinesterase inhibitors for Alzheimer's disease.Hybrids: a new paradigm to treat Alzheimer's disease.2-(2-(4-Benzoylpiperazin-1-yl)ethyl)isoindoline-1,3-dione derivatives: Synthesis, docking and acetylcholinesterase inhibitory evaluation as anti-alzheimer agents.Recent progress in repositioning Alzheimer's disease drugs based on a multitarget strategy.SAR study to find optimal cholinesterase reactivator against organophosphorous nerve agents and pesticides.Novel multitarget-directed tacrine derivatives as potential candidates for the treatment of Alzheimer's disease.Synthesis, pharmacological assessment, and molecular modeling of acetylcholinesterase/butyrylcholinesterase inhibitors: effect against amyloid-β-induced neurotoxicity.Progress in acetylcholinesterase reactivators and in the treatment of organophosphorus intoxication: a patent review (2006-2016).Halogen-directed drug design for Alzheimer's disease: a combined density functional and molecular docking study.Virtual screening and biological evaluation of piperazine derivatives as human acetylcholinesterase inhibitors.Synthesis and Acetylcholinesterase Inhibitory Evaluation of 4-(1,3-Dioxoisoindolin-2-yl)-N-Phenyl Benzamide Derivatives as Potential Anti-Alzheimer Agents.The protective effects of coumestrol against amyloid-β peptide- and lipopolysaccharide-induced toxicity on mice astrocytes.Synthesis and Evaluation of Anti-acetylcholinesterase Activity of 2-(2-(4-(2-Oxo-2-phenylethyl)piperazin-1-yl) ethyl)Isoindoline-1,3-dione Derivatives with Potential Anti-Alzheimer EffectsSynthesis, docking and acetylcholinesterase inhibitory assessment of 2-(2-(4-Benzylpiperazin-1-yl)ethyl)isoindoline-1,3-dione derivatives with potential anti-Alzheimer effects.Looking Back, Looking Forward at Halogen Bonding in Drug Discovery.Synthesis of some new 3-coumaranone and coumarin derivatives as dual inhibitors of acetyl- and butyrylcholinesterase.Divergent strategy for the synthesis of original dihydrobenzo- and dihydronaphtho-acridines.Phthalimide-Derived N-Benzylpyridinium Halides Targeting Cholinesterases: Synthesis and Bioactivity of New Potential Anti-Alzheimer's Disease Agents.Synthesis and molecular docking studies of some 4-phthalimidobenzenesulfonamide derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors.Tacrine-mefenamic acid hybrids for inhibition of acetylcholinesteraseSynthesis of 3-aminocoumarin--benzylpyridinium conjugates with nanomolar inhibitory activity against acetylcholinesterase
P2860
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P2860
Donepezil-tacrine hybrid related derivatives as new dual binding site inhibitors of AChE.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Donepezil-tacrine hybrid related derivatives as new dual binding site inhibitors of AChE.
@en
type
label
Donepezil-tacrine hybrid related derivatives as new dual binding site inhibitors of AChE.
@en
prefLabel
Donepezil-tacrine hybrid related derivatives as new dual binding site inhibitors of AChE.
@en
P2093
P50
P1476
Donepezil-tacrine hybrid related derivatives as new dual binding site inhibitors of AChE
@en
P2093
Del Monte M
Dorronsoro I
García-Palomero E
P304
P356
10.1016/J.BMC.2005.09.029
P407
P577
2005-10-17T00:00:00Z