Adverse physicochemical properties of tripalmitin in beta cells lead to morphological changes and lipotoxicity in vitro.
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Exploring the metabolic syndrome: Nonalcoholic fatty pancreas diseaseCyclical and alternating infusions of glucose and intralipid in rats inhibit insulin gene expression and Pdx-1 binding in islets.Susceptibility of pancreatic beta cells to fatty acids is regulated by LXR/PPARalpha-dependent stearoyl-coenzyme A desaturase.De novo lipogenesis and stearoyl-CoA desaturase are coordinately regulated in the human adipocyte and protect against palmitate-induced cell injury.Cellular stress responses: cell survival and cell deathα-Linolenic acid prevents endoplasmic reticulum stress-mediated apoptosis of stearic acid lipotoxicity on primary rat hepatocytesReduced endoplasmic reticulum luminal calcium links saturated fatty acid-mediated endoplasmic reticulum stress and cell death in liver cells.Short-term effects of dietary fatty acids on muscle lipid composition and serum acylcarnitine profile in human subjects.Islet beta cell failure in type 2 diabetesEndoplasmic reticulum stress and the unfolded protein response in nonalcoholic fatty liver disease.De novo lipogenesis in the differentiating human adipocyte can provide all fatty acids necessary for maturation.Lipid mixtures containing a very high proportion of saturated fatty acids only modestly impair insulin signaling in cultured muscle cells.Transcriptional analysis reveals a high impact of conjugated linoleic acid on stearoyl-Coenzyme A desaturase 1 mRNA expression in mice gastrocnemius muscle.The Transcription Factor p8 Regulates Autophagy in Response to Palmitic Acid Stress via a Mammalian Target of Rapamycin (mTOR)-independent Signaling PathwayIslet β cell mass in diabetes and how it relates to function, birth, and death.Long-term exposure of mouse pancreatic islets to oleate or palmitate results in reduced glucose-induced somatostatin and oversecretion of glucagonThe role of fatty acids in the development and progression of nonalcoholic fatty liver disease.Initiation and execution of lipotoxic ER stress in pancreatic beta-cells.Proteins altered by elevated levels of palmitate or glucose implicated in impaired glucose-stimulated insulin secretion.As a matter of fat.A functional, genome-wide evaluation of liposensitive yeast identifies the "ARE2 required for viability" (ARV1) gene product as a major component of eukaryotic fatty acid resistanceFatty acids and the endoplasmic reticulum in nonalcoholic fatty liver diseaseIs fat so bad? Modulation of endoplasmic reticulum stress by lipid droplet formation.The role of lipid droplet formation in the protection of unsaturated fatty acids against palmitic acid induced lipotoxicity to rat insulin-producing cells.UPR in palmitate-treated pancreatic beta-cells is not affected by altering oxidation of the fatty acidThe role of ER stress in lipid metabolism and lipotoxicity.Endoplasmic reticulum stress in obesity and obesity-related disorders: An expanded view.Cell death-inducing DFF45-like effector b (Cideb) is present in pancreatic beta-cells and involved in palmitate induced beta-cell apoptosis.Structural requirements for the cytoprotective actions of mono-unsaturated fatty acids in the pancreatic beta-cell line, BRIN-BD11Interruption of triacylglycerol synthesis in the endoplasmic reticulum is the initiating event for saturated fatty acid-induced lipotoxicity in liver cells.Fatty acid-mediated endoplasmic reticulum stress in vivo: differential response to the infusion of Soybean and Lard Oil in rats.Differential activation of ER stress and apoptosis in response to chronically elevated free fatty acids in pancreatic beta-cells.Mechanisms involved in the cytotoxic and cytoprotective actions of saturated versus monounsaturated long-chain fatty acids in pancreatic beta-cells.Effect of α-linolenic acid on endoplasmic reticulum stress-mediated apoptosis of palmitic acid lipotoxicity in primary rat hepatocytes.Peroxisome proliferator-activated receptor alpha-retinoid X receptor agonists induce beta-cell protection against palmitate toxicity.Effects of Dietary Fatty Acids in Pancreatic Beta Cell Metabolism, Implications in Homeostasis.
P2860
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P2860
Adverse physicochemical properties of tripalmitin in beta cells lead to morphological changes and lipotoxicity in vitro.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Adverse physicochemical proper ...... ges and lipotoxicity in vitro.
@en
type
label
Adverse physicochemical proper ...... ges and lipotoxicity in vitro.
@en
prefLabel
Adverse physicochemical proper ...... ges and lipotoxicity in vitro.
@en
P2093
P1433
P1476
Adverse physicochemical proper ...... ges and lipotoxicity in vitro.
@en
P2093
B A Fielding
J H Moffitt
J M Currie
R Evershed
P2888
P304
P356
10.1007/S00125-005-1861-9
P577
2005-08-11T00:00:00Z